/ The Business Master (3rd Edition) / The Business Master (3rd Edition).iso / files / wordmisc / jeprs / jeeprs25.exe / REF1.JPR

< prev

next >

view JSON data

view as text

open on a Mac

open on a PC

+--------+-------------------------+-------------------------+--------+--------+
|00000000| 4a 45 50 52 53 20 52 65 | 66 65 72 65 6e 63 65 20 |JEPRS Re|ference |
|00000010| 46 69 6c 65 00 0a 1a 22 | 00 00 00 6d 00 03 00 02 |File..."|...m....|
|00000020| 01 14 00 00 00 00 00 00 | 00 00 00 00 00 00 00 00 |........|........|
|00000030| 00 00 00 00 00 00 00 00 | 00 00 00 00 00 00 00 00 |........|........|
|00000040| 00 00 00 00 00 00 00 00 | 00 00 00 00 00 00 00 00 |........|........|
|00000050| 00 00 00 00 00 00 00 00 | 00 00 00 00 00 00 00 00 |........|........|
|00000060| 00 00 00 00 07 01 00 01 | 71 12 05 03 08 05 02 01 |........|q.......|
|00000070| 01 00 00 49 73 6f 6c 61 | 74 69 6f 6e 20 6f 66 20 |...Isola|tion of |
|00000080| 74 72 61 6e 73 63 72 69 | 70 74 69 6f 6e 20 66 61 |transcri|ption fa|
|00000090| 63 74 6f 72 73 20 74 68 | 61 74 20 64 69 73 63 72 |ctors th|at discr|
|000000a0| 69 6d 69 6e 61 74 65 20 | 62 65 74 77 65 65 6e 20 |iminate |between |
|000000b0| 64 69 66 66 65 72 65 6e | 74 20 70 72 6f 6d 6f 74 |differen|t promot|
|000000c0| 65 72 73 20 72 65 63 6f | 67 6e 69 7a 65 64 20 62 |ers reco|gnized b|
|000000d0| 79 20 52 4e 41 20 50 6f | 6c 79 6d 65 72 61 73 65 |y RNA Po|lymerase|
|000000e0| 20 49 49 00 44 79 6e 61 | 6e 20 57 53 2c 20 54 6a | II.Dyna|n WS, Tj|
|000000f0| 69 61 6e 20 52 00 43 65 | 6c 6c 00 33 32 00 36 36 |ian R.Ce|ll.32.66|
|00000100| 39 2d 36 38 30 00 31 39 | 38 33 00 4a 00 00 00 54 |9-680.19|83.J...T|
|00000110| 72 61 6e 73 63 72 69 70 | 74 69 6f 6e 20 46 61 63 |ranscrip|tion Fac|
|00000120| 74 6f 72 73 2c 20 52 4e | 41 20 50 6f 6c 20 49 49 |tors, RN|A Pol II|
|00000130| 00 07 02 00 01 52 19 0e | 02 0a 05 02 01 01 00 00 |.....R..|........|
|00000140| 44 65 76 65 6c 6f 70 6d | 65 6e 74 61 6c 6c 79 20 |Developm|entally |
|00000150| 52 65 67 75 6c 61 74 65 | 64 20 45 78 70 72 65 73 |Regulate|d Expres|
|00000160| 73 69 6f 6e 20 6f 66 20 | 61 20 54 72 75 6e 63 61 |sion of |a Trunca|
|00000170| 74 65 64 20 4d 79 6f 73 | 69 6e 20 4c 69 67 68 74 |ted Myos|in Light|
|00000180| 2d 43 68 61 69 6e 20 31 | 46 2f 33 46 20 47 65 6e |-Chain 1|F/3F Gen|
|00000190| 65 00 47 61 72 66 69 6e | 6b 65 6c 20 4c 49 2c 20 |e.Garfin|kel LI, |
|000001a0| 44 61 76 69 64 73 6f 6e | 20 4e 00 4d 6f 6c 20 43 |Davidson| N.Mol C|
|000001b0| 65 6c 6c 20 42 69 6f 6c | 00 37 00 33 38 32 36 2d |ell Biol|.7.3826-|
|000001c0| 33 38 32 39 00 31 39 38 | 37 00 4a 00 00 00 47 65 |3829.198|7.J...Ge|
|000001d0| 6e 65 20 45 78 70 72 65 | 73 73 69 6f 6e 3b 50 72 |ne Expre|ssion;Pr|
|000001e0| 6f 6d 6f 74 65 72 20 53 | 70 65 63 69 66 69 63 69 |omoter S|pecifici|
|000001f0| 74 79 3b 69 6e 74 72 6f | 6e 20 69 6e 74 65 72 6e |ty;intro|n intern|
|00000200| 61 6c 20 70 72 6f 6d 6f | 74 65 72 3b 72 61 74 3b |al promo|ter;rat;|
|00000210| 20 54 72 61 6e 73 63 72 | 69 70 74 69 6f 6e 3b 50 | Transcr|iption;P|
|00000220| 72 6f 6d 6f 74 65 72 20 | 49 6e 64 65 70 65 6e 64 |romoter |Independ|
|00000230| 65 6e 63 65 3b 4d 79 6f | 67 65 6e 65 73 69 73 3b |ence;Myo|genesis;|
|00000240| 6d 6f 75 73 65 3b 4d 4c | 43 2f 6d 79 6f 73 69 6e |mouse;ML|C/myosin|
|00000250| 20 6c 69 67 68 74 20 63 | 68 61 69 6e 3b 00 07 03 | light c|hain;...|
|00000260| 00 01 49 42 0e 02 0a 05 | 02 01 01 00 00 44 69 66 |..IB....|.....Dif|
|00000270| 66 65 72 65 6e 74 69 61 | 6c 20 50 61 74 74 65 72 |ferentia|l Patter|
|00000280| 6e 73 20 6f 66 20 54 72 | 61 6e 73 63 72 69 70 74 |ns of Tr|anscript|
|00000290| 20 41 63 63 75 6d 75 6c | 61 74 69 6f 6e 20 44 75 | Accumul|ation Du|
|000002a0| 72 69 6e 67 20 48 75 6d | 61 6e 20 4d 79 6f 67 65 |ring Hum|an Myoge|
|000002b0| 6e 65 73 69 73 00 47 75 | 6e 6e 69 6e 67 20 50 2c |nesis.Gu|nning P,|
|000002c0| 20 48 61 72 64 65 6d 61 | 6e 20 45 2c 20 57 61 64 | Hardema|n E, Wad|
|000002d0| 65 20 52 2c 20 50 6f 6e | 74 65 20 50 2c 20 42 61 |e R, Pon|te P, Ba|
|000002e0| 69 6e 73 20 57 2c 20 42 | 6c 61 75 20 48 4d 2c 20 |ins W, B|lau HM, |
|000002f0| 4b 65 64 65 73 20 4c 00 | 4d 6f 6c 20 43 65 6c 6c |Kedes L.|Mol Cell|
|00000300| 20 42 69 6f 6c 00 37 00 | 34 31 30 30 2d 34 31 31 | Biol.7.|4100-411|
|00000310| 34 00 31 39 38 37 00 4a | 00 00 00 43 6f 6f 72 64 |4.1987.J|...Coord|
|00000320| 69 6e 61 74 65 20 52 65 | 67 75 6c 61 74 69 6f 6e |inate Re|gulation|
|00000330| 3b 20 43 6f 6f 72 64 69 | 6e 61 74 65 20 54 72 61 |; Coordi|nate Tra|
|00000340| 6e 73 63 72 69 70 74 69 | 6f 6e 3b 20 47 65 6e 65 |nscripti|on; Gene|
|00000350| 20 53 65 74 73 3b 20 4d | 79 6f 67 65 6e 65 73 69 | Sets; M|yogenesi|
|00000360| 73 3b 20 53 61 74 65 6c | 6c 69 74 65 20 43 65 6c |s; Satel|lite Cel|
|00000370| 6c 73 3b 20 53 61 72 63 | 6f 6d 65 72 65 20 41 73 |ls; Sarc|omere As|
|00000380| 73 65 6d 62 6c 79 00 07 | 04 00 01 4a 0a 0c 04 08 |sembly..|...J....|
|00000390| 05 02 01 01 00 00 54 68 | 65 20 41 6d 70 6c 69 66 |......Th|e Amplif|
|000003a0| 69 65 64 20 45 78 70 72 | 65 73 73 69 6f 6e 20 6f |ied Expr|ession o|
|000003b0| 66 20 46 61 63 74 6f 72 | 73 20 52 65 67 75 6c 61 |f Factor|s Regula|
|000003c0| 74 69 6e 67 20 4d 79 6f | 67 65 6e 65 73 69 73 20 |ting Myo|genesis |
|000003d0| 69 6e 20 4c 36 20 4d 79 | 6f 62 6c 61 73 74 73 00 |in L6 My|oblasts.|
|000003e0| 57 72 69 67 68 74 20 57 | 45 00 4a 20 43 65 6c 6c |Wright W|E.J Cell|
|000003f0| 20 42 69 6f 6c 00 31 30 | 30 00 33 31 31 2d 33 31 | Biol.10|0.311-31|
|00000400| 36 00 31 39 38 35 00 4a | 00 00 00 42 55 64 52 3b |6.1985.J|...BUdR;|
|00000410| 20 4d 79 6f 67 65 6e 65 | 73 69 73 3b 20 52 65 67 | Myogene|sis; Reg|
|00000420| 75 6c 61 74 6f 72 79 20 | 46 61 63 74 6f 72 73 3b |ulatory |Factors;|
|00000430| 20 44 69 66 66 65 72 65 | 6e 74 69 61 74 69 6f 6e | Differe|ntiation|
|00000440| 2d 44 65 66 65 63 74 69 | 76 65 3b 20 4f 76 65 72 |-Defecti|ve; Over|
|00000450| 70 72 6f 64 75 63 65 72 | 73 3b 20 49 6e 68 69 62 |producer|s; Inhib|
|00000460| 69 74 69 6f 6e 20 6f 66 | 20 44 69 66 66 65 72 65 |ition of| Differe|
|00000470| 6e 74 69 61 74 69 6f 6e | 00 07 05 00 01 2a 0a 0c |ntiation|.....*..|
|00000480| 03 08 05 02 01 01 00 00 | 49 6e 64 75 63 74 69 6f |........|Inductio|
|00000490| 6e 20 6f 66 20 4d 75 73 | 63 6c 65 20 47 65 6e 65 |n of Mus|cle Gene|
|000004a0| 73 20 69 6e 20 4e 65 75 | 72 61 6c 20 43 65 6c 6c |s in Neu|ral Cell|
|000004b0| 73 00 57 72 69 67 68 74 | 20 57 45 00 4a 20 43 65 |s.Wright| WE.J Ce|
|000004c0| 6c 6c 20 42 69 6f 6c 00 | 39 38 00 34 32 37 2d 34 |ll Biol.|98.427-4|
|000004d0| 33 35 00 31 39 38 34 00 | 4a 00 00 00 4d 79 6f 67 |35.1984.|J...Myog|
|000004e0| 65 6e 65 73 69 73 3b 20 | 48 65 74 65 72 6f 6b 61 |enesis; |Heteroka|
|000004f0| 72 79 6f 6e 73 3b 20 43 | 68 69 63 6b 3b 20 52 61 |ryons; C|hick; Ra|
|00000500| 74 20 53 6b 65 6c 65 74 | 61 6c 20 4d 79 6f 73 69 |t Skelet|al Myosi|
|00000510| 6e 20 4c 69 67 68 74 20 | 43 68 61 69 6e 73 20 2f |n Light |Chains /|
|00000520| 4d 4c 43 3b 20 54 72 61 | 6e 73 64 69 66 66 65 72 |MLC; Tra|nsdiffer|
|00000530| 65 6e 74 69 61 74 69 6f | 6e 3b 20 49 6e 64 75 63 |entiatio|n; Induc|
|00000540| 69 6e 67 20 46 61 63 74 | 6f 72 73 3b 20 44 69 66 |ing Fact|ors; Dif|
|00000550| 66 65 72 65 6e 74 69 61 | 74 69 6f 6e 20 53 75 70 |ferentia|tion Sup|
|00000560| 70 72 65 73 73 69 6f 6e | 3b 00 07 06 00 01 30 08 |pression|;.....0.|
|00000570| 07 04 08 05 02 01 01 00 | 00 54 72 61 6e 73 63 72 |........|.Transcr|
|00000580| 69 70 74 69 6f 6e 20 6f | 66 20 58 65 6e 6f 70 75 |iption o|f Xenopu|
|00000590| 73 20 35 53 20 72 69 62 | 6f 73 6f 6d 61 6c 20 52 |s 5S rib|osomal R|
|000005a0| 4e 41 20 67 65 6e 65 73 | 00 4b 6f 72 6e 20 4c 4a |NA genes|.Korn LJ|
|000005b0| 00 4e 61 74 75 72 65 00 | 32 39 35 00 31 30 31 2d |.Nature.|295.101-|
|000005c0| 31 30 35 00 31 39 38 32 | 00 4a 00 00 00 00 07 07 |105.1982|.J......|
|000005d0| 00 01 41 17 11 04 05 05 | 02 01 15 00 00 4f 72 67 |..A.....|.....Org|
|000005e0| 61 6e 69 7a 61 74 69 6f | 6e 20 61 6e 64 20 74 72 |anizatio|n and tr|
|000005f0| 61 6e 73 63 72 69 70 74 | 69 6f 6e 20 6f 66 20 58 |anscript|ion of X|
|00000600| 65 6e 6f 70 75 73 20 35 | 53 20 72 69 62 6f 73 6f |enopus 5|S riboso|
|00000610| 6d 61 6c 20 52 4e 41 20 | 67 65 6e 65 73 00 4b 6f |mal RNA |genes.Ko|
|00000620| 72 6e 20 4c 4a 2c 20 42 | 6f 67 65 6e 68 61 67 65 |rn LJ, B|ogenhage|
|00000630| 6e 20 44 46 00 54 68 65 | 20 43 65 6c 6c 20 4e 75 |n DF.The| Cell Nu|
|00000640| 63 6c 65 75 73 00 58 49 | 49 00 31 2d 32 39 00 31 |cleus.XI|I.1-29.1|
|00000650| 39 38 32 00 42 00 00 41 | 63 61 64 65 6d 69 63 20 |982.B..A|cademic |
|00000660| 50 72 65 73 73 2c 20 49 | 6e 63 2e 00 45 64 69 74 |Press, I|nc..Edit|
|00000670| 6f 72 20 6e 6f 74 20 63 | 75 72 72 65 6e 74 6c 79 |or not c|urrently|
|00000680| 20 6b 6e 6f 77 6e 2c 20 | 6e 6f 72 20 61 64 64 72 | known, |nor addr|
|00000690| 65 73 73 20 6f 66 20 70 | 75 62 6c 69 73 68 65 72 |ess of p|ublisher|
|000006a0| 00 07 00 00 01 65 1d 10 | 01 08 05 02 01 3d 00 00 |.....e..|.....=..|
|000006b0| 41 20 70 72 6f 74 65 69 | 6e 20 66 61 63 74 6f 72 |A protei|n factor|
|000006c0| 20 72 65 67 75 6c 61 74 | 65 73 20 74 72 61 6e 73 | regulat|es trans|
|000006d0| 63 72 69 70 74 69 6f 6e | 20 6f 66 20 74 68 65 20 |cription| of the |
|000006e0| 58 65 6e 6f 70 75 73 20 | 35 53 20 72 69 62 6f 73 |Xenopus |5S ribos|
|000006f0| 6f 6d 61 6c 20 52 4e 41 | 20 67 65 6e 65 73 20 69 |omal RNA| genes i|
|00000700| 6e 20 61 20 70 6f 73 69 | 74 69 76 65 20 66 61 73 |n a posi|tive fas|
|00000710| 68 69 6f 6e 00 50 72 69 | 63 65 20 4a 2c 20 46 61 |hion.Pri|ce J, Fa|
|00000720| 72 6e 68 61 6d 20 50 4a | 2c 20 4b 6f 72 6e 20 4c |rnham PJ|, Korn L|
|00000730| 4a 00 47 65 6e 65 20 45 | 78 70 72 65 73 73 69 6f |J.Gene E|xpressio|
|00000740| 6e 00 00 32 37 33 2d 32 | 38 31 00 31 39 38 33 00 |n..273-2|81.1983.|
|00000750| 42 00 00 41 6c 61 6e 20 | 52 2e 20 4c 69 73 73 2c |B..Alan |R. Liss,|
|00000760| 20 49 6e 63 2e 2c 20 31 | 35 30 20 46 69 66 74 68 | Inc., 1|50 Fifth|
|00000770| 20 41 76 65 6e 75 65 2c | 20 4e 65 77 20 59 6f 72 | Avenue,| New Yor|
|00000780| 6b 2c 20 4e 59 20 31 30 | 30 31 31 20 55 53 41 00 |k, NY 10|011 USA.|
|00000790| 00 07 09 00 01 63 13 07 | 04 08 05 02 01 01 00 00 |.....c..|........|
|000007a0| 54 68 65 20 72 65 61 63 | 74 69 76 61 74 69 6f 6e |The reac|tivation|
|000007b0| 20 6f 66 20 64 65 76 65 | 6c 6f 70 6d 65 6e 74 61 | of deve|lopmenta|
|000007c0| 6c 6c 79 20 69 6e 65 72 | 74 20 35 53 20 67 65 6e |lly iner|t 5S gen|
|000007d0| 65 73 20 69 6e 20 73 6f | 6d 61 74 69 63 20 6e 75 |es in so|matic nu|
|000007e0| 63 6c 65 69 20 69 6e 6a | 65 63 74 65 64 20 69 6e |clei inj|ected in|
|000007f0| 74 6f 20 58 65 6e 6f 70 | 75 73 20 6f 6f 63 79 74 |to Xenop|us oocyt|
|00000800| 65 73 00 4b 6f 72 6e 20 | 4c 4a 2c 20 47 75 72 64 |es.Korn |LJ, Gurd|
|00000810| 6f 6e 20 4a 42 00 4e 61 | 74 75 72 65 00 32 38 39 |on JB.Na|ture.289|
|00000820| 00 34 36 31 2d 34 36 36 | 00 31 39 38 31 00 4a 00 |.461-466|.1981.J.|
|00000830| 00 00 00 07 00 00 01 44 | 22 12 06 08 05 02 01 01 |.......D|".......|
|00000840| 00 00 54 72 61 6e 73 63 | 72 69 70 74 69 6f 6e 20 |..Transc|ription |
|00000850| 69 6e 69 74 69 61 74 69 | 6f 6e 20 6f 66 20 58 65 |initiati|on of Xe|
|00000860| 6e 6f 70 75 73 20 35 53 | 20 72 69 62 6f 73 6f 6d |nopus 5S| ribosom|
|00000870| 61 6c 20 52 4e 41 20 67 | 65 6e 65 73 20 69 6e 20 |al RNA g|enes in |
|00000880| 76 69 74 72 6f 00 4b 6f | 72 6e 20 4c 4a 2c 20 42 |vitro.Ko|rn LJ, B|
|00000890| 69 72 6b 65 6e 6d 65 69 | 65 72 20 45 48 2c 20 42 |irkenmei|er EH, B|
|000008a0| 72 6f 77 6e 20 44 44 00 | 4e 75 63 6c 65 69 63 20 |rown DD.|Nucleic |
|000008b0| 41 63 69 64 73 20 52 65 | 73 00 37 2c 20 23 34 00 |Acids Re|s.7, #4.|
|000008c0| 39 34 37 2d 39 35 38 00 | 31 39 37 39 00 4a 00 00 |947-958.|1979.J..|
|000008d0| 00 00 07 0b 00 01 35 0e | 07 04 08 05 02 01 01 00 |......5.|........|
|000008e0| 00 52 4e 41 20 70 6f 6c | 79 6d 65 72 61 73 65 20 |.RNA pol|ymerase |
|000008f0| 49 20 70 72 6f 6d 6f 74 | 65 72 73 20 61 6e 64 20 |I promot|ers and |
|00000900| 74 72 61 6e 73 63 72 69 | 70 74 69 6f 6e 20 66 61 |transcri|ption fa|
|00000910| 63 74 6f 72 73 00 53 6f | 6d 6d 65 72 76 69 6c 6c |ctors.So|mmervill|
|00000920| 65 20 4a 00 4e 61 74 75 | 72 65 00 33 31 30 00 31 |e J.Natu|re.310.1|
|00000930| 38 39 2d 31 39 30 00 31 | 39 38 34 00 4a 00 00 00 |89-190.1|984.J...|
|00000940| 52 65 76 69 65 77 3b 52 | 4e 41 20 70 6f 6c 20 49 |Review;R|NA pol I|
|00000950| 3b 74 72 61 6e 73 63 72 | 69 70 74 69 6f 6e 20 66 |;transcr|iption f|
|00000960| 61 63 74 6f 72 73 3b 74 | 72 61 6e 73 2d 61 63 74 |actors;t|rans-act|
|00000970| 69 6e 67 20 66 61 63 74 | 6f 72 73 3b 20 69 6e 74 |ing fact|ors; int|
|00000980| 65 72 6e 61 6c 20 70 72 | 6f 6d 6f 74 65 72 73 3b |ernal pr|omoters;|
|00000990| 00 07 0c 00 01 2d 0c 07 | 04 08 05 02 01 01 00 00 |.....-..|........|
|000009a0| 47 65 6c 20 65 6c 65 63 | 74 72 6f 70 68 6f 72 65 |Gel elec|trophore|
|000009b0| 73 69 73 20 6f 66 20 70 | 72 6f 74 65 69 6e 2d 44 |sis of p|rotein-D|
|000009c0| 4e 41 20 63 6f 6d 70 6c | 65 78 65 73 00 43 72 6f |NA compl|exes.Cro|
|000009d0| 74 68 65 72 73 20 44 4d | 00 4e 61 74 75 72 65 00 |thers DM|.Nature.|
|000009e0| 33 32 35 00 34 36 34 2d | 34 36 35 00 31 39 38 37 |325.464-|465.1987|
|000009f0| 00 4a 00 00 00 47 65 6c | 20 52 65 74 61 72 64 61 |.J...Gel| Retarda|
|00000a00| 74 69 6f 6e 20 41 73 73 | 61 79 3b 20 42 61 6e 64 |tion Ass|ay; Band|
|00000a10| 2d 53 68 69 66 74 20 41 | 73 73 61 79 3b 20 44 4e |-Shift A|ssay; DN|
|00000a20| 41 2d 42 69 6e 64 69 6e | 67 20 50 72 6f 74 65 69 |A-Bindin|g Protei|
|00000a30| 6e 73 3b 20 4d 65 74 68 | 6f 64 73 3b 70 72 6f 74 |ns; Meth|ods;prot|
|00000a40| 65 69 6e 2d 44 4e 41 20 | 69 6e 74 65 72 61 63 74 |ein-DNA |interact|
|00000a50| 69 6f 6e 73 3b 00 07 0d | 00 01 41 0b 10 03 02 05 |ions;...|..A.....|
|00000a60| 02 01 16 00 00 4d 65 63 | 68 61 6e 69 73 6d 20 61 |.....Mec|hanism a|
|00000a70| 6e 64 20 63 6f 6e 74 72 | 6f 6c 20 6f 66 20 74 72 |nd contr|ol of tr|
|00000a80| 61 6e 73 63 72 69 70 74 | 69 6f 6e 20 69 6e 69 74 |anscript|ion init|
|00000a90| 69 61 74 69 6f 6e 20 69 | 6e 20 70 72 6f 6b 61 72 |iation i|n prokar|
|00000aa0| 79 6f 74 65 73 00 4d 63 | 43 6c 75 72 65 20 57 52 |yotes.Mc|Clure WR|
|00000ab0| 00 41 6e 6e 20 52 65 76 | 20 42 69 6f 63 68 65 6d |.Ann Rev| Biochem|
|00000ac0| 00 35 34 00 3f 00 31 39 | 38 35 00 42 00 00 41 6e |.54.?.19|85.B..An|
|00000ad0| 6e 75 61 6c 20 52 65 76 | 69 65 77 73 2c 20 49 6e |nual Rev|iews, In|
|00000ae0| 63 2e 3f 00 52 65 61 64 | 20 66 6f 72 20 57 65 73 |c.?.Read| for Wes|
|00000af0| 20 48 61 74 66 69 65 6c | 64 27 73 20 6c 61 62 20 | Hatfiel|d's lab |
|00000b00| 72 6f 74 61 74 69 6f 6e | 3b 20 52 65 76 69 65 77 |rotation|; Review|
|00000b10| 3b 00 07 0e 00 01 63 16 | 0c 09 0a 05 02 01 01 00 |;.....c.|........|
|00000b20| 00 45 66 66 65 63 74 73 | 20 6f 66 20 70 72 6f 6d |.Effects| of prom|
|00000b30| 6f 74 65 72 20 73 74 72 | 65 6e 67 74 68 73 20 61 |oter str|engths a|
|00000b40| 6e 64 20 67 72 6f 77 74 | 68 20 63 6f 6e 64 69 74 |nd growt|h condit|
|00000b50| 69 6f 6e 73 20 6f 6e 20 | 63 6f 70 79 20 6e 75 6d |ions on |copy num|
|00000b60| 62 65 72 20 6f 66 20 74 | 72 61 6e 73 63 72 69 70 |ber of t|ranscrip|
|00000b70| 74 69 6f 6e 2d 66 75 73 | 69 6f 6e 20 76 65 63 74 |tion-fus|ion vect|
|00000b80| 6f 72 73 00 41 64 61 6d | 73 20 43 57 2c 20 48 61 |ors.Adam|s CW, Ha|
|00000b90| 74 66 69 65 6c 64 20 47 | 57 00 4a 20 42 69 6f 6c |tfield G|W.J Biol|
|00000ba0| 20 43 68 65 6d 00 32 35 | 39 2c 20 23 31 32 00 37 | Chem.25|9, #12.7|
|00000bb0| 33 39 39 2d 37 34 30 33 | 00 31 39 38 34 00 4a 00 |399-7403|.1984.J.|
|00000bc0| 00 00 55 73 65 64 20 66 | 6f 72 20 45 72 69 63 20 |..Used f|or Eric |
|00000bd0| 53 74 61 6e 62 72 69 64 | 67 65 27 73 20 72 6f 74 |Stanbrid|ge's rot|
|00000be0| 61 74 69 6f 6e 3a 20 20 | 76 61 72 69 65 64 20 70 |ation:  |varied p|
|00000bf0| 72 6f 63 65 64 75 72 65 | 20 66 6f 72 20 44 4e 41 |rocedure| for DNA|
|00000c00| 20 65 78 74 72 61 63 74 | 69 6f 6e 3b 20 4d 65 74 | extract|ion; Met|
|00000c10| 68 6f 64 73 00 07 0f 00 | 01 43 16 08 04 08 05 02 |hods....|.C......|
|00000c20| 01 01 00 00 4d 75 6c 74 | 69 70 6c 65 20 6d 65 63 |....Mult|iple mec|
|00000c30| 68 61 6e 69 73 6d 73 20 | 6f 66 20 70 72 6f 74 65 |hanisms |of prote|
|00000c40| 69 6e 20 69 6e 73 65 72 | 74 69 6f 6e 20 69 6e 74 |in inser|tion int|
|00000c50| 6f 20 61 6e 64 20 61 63 | 72 6f 73 73 20 6d 65 6d |o and ac|ross mem|
|00000c60| 62 72 61 6e 65 73 00 57 | 69 63 6b 6e 65 72 20 57 |branes.W|ickner W|
|00000c70| 54 2c 20 4c 6f 64 69 73 | 68 20 48 46 00 53 63 69 |T, Lodis|h HF.Sci|
|00000c80| 65 6e 63 65 00 32 33 30 | 00 34 30 30 2d 34 30 37 |ence.230|.400-407|
|00000c90| 00 31 39 38 35 00 4a 00 | 00 00 55 43 20 49 72 76 |.1985.J.|..UC Irv|
|00000ca0| 69 6e 65 20 4d 69 63 72 | 6f 62 69 6f 6c 6f 67 79 |ine Micr|obiology|
|00000cb0| 20 26 20 4d 6f 6c 65 63 | 75 6c 61 72 20 47 65 6e | & Molec|ular Gen|
|00000cc0| 65 74 69 63 73 20 54 75 | 74 6f 72 69 61 6c 20 43 |etics Tu|torial C|
|00000cd0| 6c 61 73 73 2c 20 57 69 | 6e 74 65 72 20 51 75 61 |lass, Wi|nter Qua|
|00000ce0| 72 74 65 72 20 31 39 38 | 36 00 07 10 00 01 2c 21 |rter 198|6.....,!|
|00000cf0| 10 02 08 05 02 01 01 00 | 00 45 6e 68 61 6e 63 65 |........|.Enhance|
|00000d00| 72 73 20 61 6e 64 20 65 | 75 6b 61 72 79 6f 74 69 |rs and e|ukaryoti|
|00000d10| 63 20 67 65 6e 65 20 74 | 72 61 6e 73 63 72 69 70 |c gene t|ranscrip|
|00000d20| 74 69 6f 6e 00 53 65 72 | 66 6c 69 6e 67 20 45 2c |tion.Ser|fling E,|
|00000d30| 20 4a 61 73 69 6e 20 4d | 2c 20 53 63 68 61 66 66 | Jasin M|, Schaff|
|00000d40| 6e 65 72 20 57 00 54 72 | 65 6e 64 73 20 69 6e 20 |ner W.Tr|ends in |
|00000d50| 47 65 6e 65 74 00 31 00 | 32 32 34 2d 32 33 30 00 |Genet.1.|224-230.|
|00000d60| 31 39 38 35 00 4a 00 00 | 00 52 65 76 69 65 77 3b |1985.J..|.Review;|
|00000d70| 67 65 6e 65 20 74 72 61 | 6e 73 63 72 69 70 74 69 |gene tra|nscripti|
|00000d80| 6f 6e 3b 67 65 6e 65 20 | 65 78 70 72 65 73 73 69 |on;gene |expressi|
|00000d90| 6f 6e 3b 65 6e 68 61 6e | 63 65 72 73 3b 65 75 6b |on;enhan|cers;euk|
|00000da0| 61 72 79 6f 74 65 73 3b | 20 74 72 61 6e 73 2d 61 |aryotes;| trans-a|
|00000db0| 63 74 69 6e 67 20 66 61 | 63 74 6f 72 73 3b 63 69 |cting fa|ctors;ci|
|00000dc0| 73 20 72 65 67 75 6c 61 | 74 6f 72 79 20 73 65 71 |s regula|tory seq|
|00000dd0| 75 65 6e 63 65 73 3b 70 | 72 6f 6d 6f 74 65 72 73 |uences;p|romoters|
|00000de0| 3b 53 56 34 30 3b 70 72 | 6f 6b 61 72 79 6f 74 65 |;SV40;pr|okaryote|
|00000df0| 73 3b 00 07 11 00 01 4d | 21 17 03 0a 05 02 01 01 |s;.....M|!.......|
|00000e00| 00 00 41 62 69 6c 69 74 | 79 20 6f 66 20 72 65 63 |..Abilit|y of rec|
|00000e10| 41 20 70 72 6f 74 65 69 | 6e 20 74 6f 20 70 72 6f |A protei|n to pro|
|00000e20| 6d 6f 74 65 20 61 20 73 | 65 61 72 63 68 20 66 6f |mote a s|earch fo|
|00000e30| 72 20 72 61 72 65 20 73 | 65 71 75 65 6e 63 65 73 |r rare s|equences|
|00000e40| 20 69 6e 20 64 75 70 6c | 65 78 20 44 4e 41 00 48 | in dupl|ex DNA.H|
|00000e50| 6f 6e 69 67 62 65 72 67 | 20 53 4d 2c 20 52 61 6f |onigberg| SM, Rao|
|00000e60| 20 42 4a 2c 20 52 61 64 | 64 69 6e 67 20 43 4d 00 | BJ, Rad|ding CM.|
|00000e70| 50 72 6f 63 20 4e 61 74 | 6c 20 41 63 61 64 20 53 |Proc Nat|l Acad S|
|00000e80| 63 69 20 55 53 41 00 38 | 33 00 39 35 38 36 2d 39 |ci USA.8|3.9586-9|
|00000e90| 35 39 30 00 31 39 38 36 | 00 4a 00 00 00 52 65 63 |590.1986|.J...Rec|
|00000ea0| 41 20 50 72 6f 74 65 69 | 6e 3b 20 44 4e 41 20 48 |A Protei|n; DNA H|
|00000eb0| 79 62 72 69 64 69 7a 61 | 74 69 6f 6e 3b 20 4d 65 |ybridiza|tion; Me|
|00000ec0| 74 68 6f 64 73 3b 20 4c | 69 62 72 61 72 79 20 45 |thods; L|ibrary E|
|00000ed0| 6e 72 69 63 68 6d 65 6e | 74 00 07 12 00 01 7f 25 |nrichmen|t......%|
|00000ee0| 17 03 0a 05 02 01 01 00 | 00 54 72 61 6e 73 63 72 |........|.Transcr|
|00000ef0| 69 70 74 69 6f 6e 20 66 | 61 63 74 6f 72 20 53 70 |iption f|actor Sp|
|00000f00| 31 20 72 65 63 6f 67 6e | 69 7a 65 73 20 70 72 6f |1 recogn|izes pro|
|00000f10| 6d 6f 74 65 72 20 73 65 | 71 75 65 6e 63 65 73 20 |moter se|quences |
|00000f20| 66 72 6f 6d 20 74 68 65 | 20 6d 6f 6e 6b 65 79 20 |from the| monkey |
|00000f30| 67 65 6e 6f 6d 65 20 74 | 68 61 74 20 61 72 65 20 |genome t|hat are |
|00000f40| 73 69 6d 69 6c 61 72 20 | 74 6f 20 74 68 65 20 73 |similar |to the s|
|00000f50| 69 6d 69 61 6e 20 76 69 | 72 75 73 20 34 30 20 70 |imian vi|rus 40 p|
|00000f60| 72 6f 6d 6f 74 65 72 00 | 44 79 6e 61 6e 20 57 53 |romoter.|Dynan WS|
|00000f70| 2c 20 53 61 66 66 65 72 | 20 4a 44 2c 20 4c 65 65 |, Saffer| JD, Lee|
|00000f80| 20 57 53 2c 20 54 6a 69 | 61 6e 20 52 00 50 72 6f | WS, Tji|an R.Pro|
|00000f90| 63 20 4e 61 74 6c 20 41 | 63 61 64 20 53 63 69 20 |c Natl A|cad Sci |
|00000fa0| 55 53 41 00 38 32 00 34 | 39 31 35 2d 34 39 31 39 |USA.82.4|915-4919|
|00000fb0| 00 31 39 38 35 00 4a 00 | 00 00 54 72 61 6e 73 63 |.1985.J.|..Transc|
|00000fc0| 72 69 70 74 69 6f 6e 20 | 66 61 63 74 6f 72 3b 74 |ription |factor;t|
|00000fd0| 72 61 6e 73 2d 61 63 74 | 69 6e 67 20 66 61 63 74 |rans-act|ing fact|
|00000fe0| 6f 72 73 3b 53 70 31 3b | 70 6f 6c 49 49 3b 53 56 |ors;Sp1;|polII;SV|
|00000ff0| 34 30 20 70 72 6f 6d 6f | 74 65 72 3b 20 6d 65 74 |40 promo|ter; met|
|00001000| 68 6f 64 73 3b 44 4e 61 | 73 65 20 70 72 6f 74 65 |hods;DNa|se prote|
|00001010| 63 74 69 6f 6e 2f 44 4e | 41 20 66 6f 6f 74 70 72 |ction/DN|A footpr|
|00001020| 69 6e 74 69 6e 67 3b 6e | 75 63 6c 65 61 73 65 20 |inting;n|uclease |
|00001030| 53 31 3b 54 41 54 41 20 | 62 6f 78 3b 47 43 20 62 |S1;TATA |box;GC b|
|00001040| 6f 78 3b 00 07 13 00 01 | 46 2a 17 03 0a 05 02 01 |ox;.....|F*......|
|00001050| 01 00 00 52 61 70 69 64 | 20 70 6c 61 73 6d 69 64 |...Rapid| plasmid|
|00001060| 20 6c 69 62 72 61 72 79 | 20 73 63 72 65 65 6e 69 | library| screeni|
|00001070| 6e 67 20 75 73 69 6e 67 | 20 52 65 63 41 2d 63 6f |ng using| RecA-co|
|00001080| 61 74 65 64 20 62 69 6f | 74 69 6e 79 6c 61 74 65 |ated bio|tinylate|
|00001090| 64 20 70 72 6f 62 65 73 | 00 52 69 67 61 73 20 42 |d probes|.Rigas B|
|000010a0| 2c 20 57 65 6c 63 68 65 | 72 20 41 41 2c 20 57 61 |, Welche|r AA, Wa|
|000010b0| 72 64 20 44 43 2c 20 57 | 65 69 73 73 6d 61 6e 20 |rd DC, W|eissman |
|000010c0| 53 4d 00 50 72 6f 63 20 | 4e 61 74 6c 20 41 63 61 |SM.Proc |Natl Aca|
|000010d0| 64 20 53 63 69 20 55 53 | 41 00 38 33 00 39 35 39 |d Sci US|A.83.959|
|000010e0| 31 2d 39 35 39 35 00 31 | 39 38 36 00 4a 00 00 00 |1-9595.1|986.J...|
|000010f0| 4d 65 74 68 6f 64 73 3b | 20 4e 75 63 6c 65 69 63 |Methods;| Nucleic|
|00001100| 20 41 63 69 64 20 49 73 | 6f 6c 61 74 69 6f 6e 3b | Acid Is|olation;|
|00001110| 20 41 76 69 64 69 6e 3b | 20 41 66 66 69 6e 69 74 | Avidin;| Affinit|
|00001120| 79 20 43 68 72 6f 6d 61 | 74 6f 67 72 61 70 68 79 |y Chroma|tography|
|00001130| 3b 20 4c 69 62 72 61 72 | 79 20 45 6e 72 69 63 68 |; Librar|y Enrich|
|00001140| 6d 65 6e 74 3b 00 07 14 | 00 01 29 0a 10 03 08 05 |ment;...|..).....|
|00001150| 02 01 15 00 00 54 68 65 | 20 70 61 74 68 77 61 79 |.....The| pathway|
|00001160| 20 6f 66 20 65 75 6b 61 | 72 79 6f 74 69 63 20 6d | of euka|ryotic m|
|00001170| 52 4e 41 20 66 6f 72 6d | 61 74 69 6f 6e 00 4e 65 |RNA form|ation.Ne|
|00001180| 76 69 6e 73 20 4a 52 00 | 41 6e 6e 20 52 65 76 20 |vins JR.|Ann Rev |
|00001190| 42 69 6f 63 68 65 6d 00 | 35 32 00 34 34 31 2d 34 |Biochem.|52.441-4|
|000011a0| 36 36 00 31 39 38 33 00 | 42 00 00 41 6e 6e 75 61 |66.1983.|B..Annua|
|000011b0| 6c 20 52 65 76 69 65 77 | 73 2c 20 49 6e 63 2e 00 |l Review|s, Inc..|
|000011c0| 6d 52 4e 41 20 70 72 6f | 63 65 73 73 69 6e 67 3b |mRNA pro|cessing;|
|000011d0| 20 73 70 6c 69 63 69 6e | 67 3b 20 63 61 70 70 69 | splicin|g; cappi|
|000011e0| 6e 67 3b 20 6d 65 74 68 | 79 6c 61 74 69 6f 6e 3b |ng; meth|ylation;|
|000011f0| 20 69 6e 69 74 69 61 74 | 69 6f 6e 3b 20 74 65 72 | initiat|ion; ter|
|00001200| 6d 69 6e 61 74 69 6f 6e | 3b 20 70 6f 6c 79 61 64 |mination|; polyad|
|00001210| 65 6e 79 6c 61 74 69 6f | 6e 3b 20 6d 52 4e 41 20 |enylatio|n; mRNA |
|00001220| 73 74 61 62 69 6c 69 74 | 79 3b 20 52 65 76 69 65 |stabilit|y; Revie|
|00001230| 77 00 07 15 00 01 21 0d | 14 0b 07 05 02 01 01 00 |w.....!.|........|
|00001240| 00 54 68 65 20 44 4e 41 | 20 68 65 6c 69 78 20 61 |.The DNA| helix a|
|00001250| 6e 64 20 68 6f 77 20 69 | 74 20 69 73 20 72 65 61 |nd how i|t is rea|
|00001260| 64 00 44 69 63 6b 65 72 | 73 6f 6e 20 52 45 00 53 |d.Dicker|son RE.S|
|00001270| 63 69 65 6e 74 69 66 69 | 63 20 41 6d 65 72 69 63 |cientifi|c Americ|
|00001280| 61 6e 00 32 34 39 2c 20 | 4e 6f 2e 20 36 00 39 34 |an.249, |No. 6.94|
|00001290| 2d 31 31 31 00 31 39 38 | 33 00 4a 00 00 00 44 4e |-111.198|3.J...DN|
|000012a0| 41 20 68 65 6c 69 78 20 | 73 74 72 75 63 74 75 72 |A helix |structur|
|000012b0| 65 3b 20 78 2d 72 61 79 | 20 63 72 79 73 74 61 6c |e; x-ray| crystal|
|000012c0| 6c 6f 67 72 61 70 68 79 | 3b 20 52 65 76 69 65 77 |lography|; Review|
|000012d0| 00 07 16 00 01 4a 30 10 | 03 08 05 02 01 15 00 00 |.....J0.|........|
|000012e0| 50 72 6f 74 65 69 6e 2d | 4e 75 63 6c 65 69 63 20 |Protein-|Nucleic |
|000012f0| 61 63 69 64 20 69 6e 74 | 65 72 61 63 74 69 6f 6e |acid int|eraction|
|00001300| 73 20 69 6e 20 74 72 61 | 6e 73 63 72 69 70 74 69 |s in tra|nscripti|
|00001310| 6f 6e 3a 20 20 41 20 6d | 6f 6c 65 63 75 6c 61 72 |on:  A m|olecular|
|00001320| 20 61 6e 61 6c 79 73 69 | 73 00 48 69 70 70 65 6c | analysi|s.Hippel|
|00001330| 20 50 48 20 76 6f 6e 2c | 20 42 65 61 72 20 44 47 | PH von,| Bear DG|
|00001340| 2c 20 4d 6f 72 67 61 6e | 20 57 44 2c 20 4d 63 53 |, Morgan| WD, McS|
|00001350| 77 69 67 67 65 6e 20 4a | 41 00 41 6e 6e 20 52 65 |wiggen J|A.Ann Re|
|00001360| 76 20 42 69 6f 63 68 65 | 6d 00 35 33 00 33 38 39 |v Bioche|m.53.389|
|00001370| 2d 34 34 36 00 31 39 38 | 34 00 42 00 00 41 6e 6e |-446.198|4.B..Ann|
|00001380| 75 61 6c 20 52 65 76 69 | 65 77 73 2c 20 49 6e 63 |ual Revi|ews, Inc|
|00001390| 2e 00 52 65 76 69 65 77 | 3b 54 72 61 6e 73 63 72 |..Review|;Transcr|
|000013a0| 69 70 74 69 6f 6e 20 69 | 6e 69 74 69 61 74 69 6f |iption i|nitiatio|
|000013b0| 6e 3b 70 72 6f 6d 6f 74 | 65 72 73 3b 6d 52 4e 41 |n;promot|ers;mRNA|
|000013c0| 20 65 6c 6f 6e 67 61 74 | 69 6f 6e 3b 6d 52 4e 41 | elongat|ion;mRNA|
|000013d0| 20 74 65 72 6d 69 6e 61 | 74 69 6f 6e 3b 70 72 6f | termina|tion;pro|
|000013e0| 6b 61 72 79 6f 74 65 73 | 3b 65 75 6b 61 72 79 6f |karyotes|;eukaryo|
|000013f0| 74 65 73 28 6e 6f 74 20 | 61 73 20 6d 75 63 68 29 |tes(not |as much)|
|00001400| 3b 70 72 6f 74 65 69 6e | 2d 44 4e 41 20 69 6e 74 |;protein|-DNA int|
|00001410| 65 72 61 63 74 69 6f 6e | 73 3b 00 07 17 00 01 41 |eraction|s;.....A|
|00001420| 30 1f 02 02 05 02 01 01 | 00 00 53 70 6c 69 63 69 |0.......|..Splici|
|00001430| 6e 67 20 6d 65 73 73 65 | 6e 67 65 72 20 52 4e 41 |ng messe|nger RNA|
|00001440| 20 70 72 65 63 75 72 73 | 6f 72 73 3a 20 20 62 72 | precurs|ors:  br|
|00001450| 61 6e 63 68 20 73 69 74 | 65 73 20 61 6e 64 20 6c |anch sit|es and l|
|00001460| 61 72 69 61 74 20 52 4e | 41 73 00 50 61 64 67 65 |ariat RN|As.Padge|
|00001470| 74 74 20 52 41 2c 20 47 | 72 61 62 6f 77 73 6b 69 |tt RA, G|rabowski|
|00001480| 20 50 4a 2c 20 4b 6f 6e | 61 72 73 6b 61 20 4d 4d | PJ, Kon|arska MM|
|00001490| 2c 20 53 68 61 72 70 20 | 50 41 00 54 72 65 6e 64 |, Sharp |PA.Trend|
|000014a0| 73 20 69 6e 20 42 69 6f | 63 68 65 6d 69 63 61 6c |s in Bio|chemical|
|000014b0| 20 53 63 69 65 6e 63 65 | 73 00 3f 00 3f 00 31 39 | Science|s.?.?.19|
|000014c0| 38 35 00 4a 00 00 00 6d | 52 4e 41 20 73 70 6c 69 |85.J...m|RNA spli|
|000014d0| 63 69 6e 67 3b 20 52 4e | 41 20 6c 61 72 69 61 74 |cing; RN|A lariat|
|000014e0| 73 3b 20 69 6e 74 65 72 | 76 65 6e 69 6e 67 20 73 |s; inter|vening s|
|000014f0| 65 71 75 65 6e 63 65 20 | 28 69 6e 74 72 6f 6e 73 |equence |(introns|
|00001500| 29 3b 20 52 65 76 69 65 | 77 00 07 18 00 01 2c 08 |); Revie|w.....,.|
|00001510| 05 03 08 05 02 01 01 00 | 00 52 4e 41 20 73 70 6c |........|.RNA spl|
|00001520| 69 63 69 6e 67 3a 20 20 | 74 68 72 65 65 20 74 68 |icing:  |three th|
|00001530| 65 6d 65 73 20 77 69 74 | 68 20 76 61 72 69 61 74 |emes wit|h variat|
|00001540| 69 6f 6e 73 00 43 65 63 | 68 20 54 52 00 43 65 6c |ions.Cec|h TR.Cel|
|00001550| 6c 00 33 34 00 37 31 33 | 2d 37 31 36 00 31 39 38 |l.34.713|-716.198|
|00001560| 33 00 4a 00 00 00 4d 69 | 6e 69 52 65 76 69 65 77 |3.J...Mi|niReview|
|00001570| 3b 52 4e 41 20 73 70 6c | 69 63 69 6e 67 3b 69 6e |;RNA spl|icing;in|
|00001580| 74 72 6f 6e 73 3b 73 70 | 6c 69 63 65 20 6a 75 6e |trons;sp|lice jun|
|00001590| 63 74 69 6f 6e 3b 44 4e | 41 20 6c 69 67 61 74 69 |ction;DN|A ligati|
|000015a0| 6f 6e 3b 00 07 19 00 01 | 41 24 05 03 08 05 02 01 |on;.....|A$......|
|000015b0| 01 00 00 54 72 61 6e 73 | 63 72 69 70 74 69 6f 6e |...Trans|cription|
|000015c0| 20 74 65 72 6d 69 6e 61 | 74 69 6f 6e 20 61 6e 64 | termina|tion and|
|000015d0| 20 33 27 20 70 72 6f 63 | 65 73 73 69 6e 67 3a 20 | 3' proc|essing: |
|000015e0| 20 54 68 65 20 65 6e 64 | 20 69 73 20 69 6e 20 73 | The end| is in s|
|000015f0| 69 74 65 00 42 69 72 6e | 73 74 65 69 6e 20 4d 4c |ite.Birn|stein ML|
|00001600| 2c 20 42 75 73 73 6c 69 | 6e 67 65 72 20 4d 2c 20 |, Bussli|nger M, |
|00001610| 53 74 72 75 62 20 4b 00 | 43 65 6c 6c 00 34 31 00 |Strub K.|Cell.41.|
|00001620| 33 34 39 2d 33 35 39 00 | 31 39 38 35 00 4a 00 00 |349-359.|1985.J..|
|00001630| 00 54 72 61 6e 73 63 72 | 69 70 74 69 6f 6e 20 74 |.Transcr|iption t|
|00001640| 65 72 6d 69 6e 61 74 69 | 6f 6e 3b 20 6d 52 4e 41 |erminati|on; mRNA|
|00001650| 20 70 72 6f 63 65 73 73 | 69 6e 67 3b 20 52 65 76 | process|ing; Rev|
|00001660| 69 65 77 00 07 1a 00 01 | 24 25 28 03 06 05 02 02 |iew.....|$%(.....|
|00001670| 15 00 00 54 72 61 6e 73 | 63 72 69 70 74 69 6f 6e |...Trans|cription|
|00001680| 20 62 79 20 52 4e 41 20 | 70 6f 6c 79 6d 65 72 61 | by RNA |polymera|
|00001690| 73 65 20 49 49 49 00 43 | 69 6c 69 62 65 72 74 6f |se III.C|iliberto|
|000016a0| 20 47 2c 20 43 61 73 74 | 61 67 6e 6f 6c 69 20 4c | G, Cast|agnoli L|
|000016b0| 2c 20 43 6f 72 74 65 73 | 65 20 52 00 43 75 72 72 |, Cortes|e R.Curr|
|000016c0| 65 6e 74 20 54 6f 70 69 | 63 73 20 69 6e 20 44 65 |ent Topi|cs in De|
|000016d0| 76 65 6c 6f 70 6d 65 6e | 74 61 6c 20 42 69 6f 6c |velopmen|tal Biol|
|000016e0| 6f 67 79 00 31 38 00 35 | 39 2d 38 38 00 31 39 38 |ogy.18.5|9-88.198|
|000016f0| 33 00 42 00 3f 00 41 63 | 61 64 65 6d 69 63 20 50 |3.B.?.Ac|ademic P|
|00001700| 72 65 73 73 2c 20 49 6e | 63 2e 00 52 4e 41 20 70 |ress, In|c..RNA p|
|00001710| 6f 6c 79 6d 65 72 61 73 | 65 20 49 49 49 3b 20 35 |olymeras|e III; 5|
|00001720| 53 20 52 4e 41 20 74 72 | 61 6e 73 63 72 69 70 74 |S RNA tr|anscript|
|00001730| 69 6f 6e 3b 20 74 52 4e | 41 20 74 72 61 6e 73 63 |ion; tRN|A transc|
|00001740| 72 69 70 74 69 6f 6e 3b | 20 56 41 20 52 4e 41 73 |ription;| VA RNAs|
|00001750| 3b 20 41 6c 75 20 73 65 | 71 75 65 6e 63 65 73 3b |; Alu se|quences;|
|00001760| 20 52 65 76 69 65 77 00 | 07 1b 00 01 6d 13 05 03 | Review.|....m...|
|00001770| 08 05 02 01 01 00 00 41 | 20 44 72 6f 73 6f 70 68 |.......A| Drosoph|
|00001780| 69 6c 61 20 52 4e 41 20 | 70 6f 6c 79 6d 65 72 61 |ila RNA |polymera|
|00001790| 73 65 20 49 49 20 74 72 | 61 6e 73 63 72 69 70 74 |se II tr|anscript|
|000017a0| 69 6f 6e 20 66 61 63 74 | 6f 72 20 63 6f 6e 74 61 |ion fact|or conta|
|000017b0| 69 6e 73 20 61 20 70 72 | 6f 6d 6f 74 65 72 2d 72 |ins a pr|omoter-r|
|000017c0| 65 67 69 6f 6e 2d 73 70 | 65 63 69 66 69 63 20 44 |egion-sp|ecific D|
|000017d0| 4e 41 2d 62 69 6e 64 69 | 6e 67 20 61 63 74 69 76 |NA-bindi|ng activ|
|000017e0| 69 74 79 00 50 61 72 6b | 65 72 20 43 53 2c 20 54 |ity.Park|er CS, T|
|000017f0| 6f 70 6f 6c 20 4a 00 43 | 65 6c 6c 00 33 36 00 33 |opol J.C|ell.36.3|
|00001800| 35 37 2d 33 36 39 00 31 | 39 38 34 00 4a 00 00 00 |57-369.1|984.J...|
|00001810| 54 72 61 6e 73 2d 61 63 | 74 69 6e 67 2f 74 72 61 |Trans-ac|ting/tra|
|00001820| 6e 73 63 72 69 70 74 69 | 6f 6e 20 66 61 63 74 6f |nscripti|on facto|
|00001830| 72 73 3b 70 6f 6c 20 49 | 49 3b 44 72 6f 73 6f 70 |rs;pol I|I;Drosop|
|00001840| 68 69 6c 61 3b 54 41 54 | 41 20 62 6f 78 3b 20 70 |hila;TAT|A box; p|
|00001850| 72 6f 6d 6f 74 65 72 3b | 65 75 6b 61 72 79 6f 74 |romoter;|eukaryot|
|00001860| 65 73 3b 44 4e 41 20 66 | 6f 6f 74 70 72 69 6e 74 |es;DNA f|ootprint|
|00001870| 69 6e 67 3b 00 07 1c 00 | 01 47 1f 1f 03 06 05 02 |ing;....|.G......|
|00001880| 01 01 00 00 50 72 6f 6d | 6f 74 65 72 2d 73 70 65 |....Prom|oter-spe|
|00001890| 63 69 66 69 63 20 61 63 | 74 69 76 61 74 69 6f 6e |cific ac|tivation|
|000018a0| 20 6f 66 20 52 4e 41 20 | 70 6f 6c 79 6d 65 72 61 | of RNA |polymera|
|000018b0| 73 65 20 49 49 20 74 72 | 61 6e 73 63 72 69 70 74 |se II tr|anscript|
|000018c0| 69 6f 6e 20 62 79 20 53 | 70 31 00 4b 61 64 6f 6e |ion by S|p1.Kadon|
|000018d0| 61 67 61 20 4a 54 2c 20 | 4a 6f 6e 65 73 20 4b 41 |aga JT, |Jones KA|
|000018e0| 2c 20 54 6a 69 61 6e 20 | 52 00 54 72 65 6e 64 73 |, Tjian |R.Trends|
|000018f0| 20 69 6e 20 42 69 6f 63 | 68 65 6d 69 63 61 6c 20 | in Bioc|hemical |
|00001900| 53 63 69 65 6e 63 65 73 | 00 31 31 00 32 30 2d 32 |Sciences|.11.20-2|
|00001910| 33 00 31 39 38 36 00 4a | 00 00 00 52 65 76 69 65 |3.1986.J|...Revie|
|00001920| 77 3b 74 72 61 6e 73 63 | 72 69 70 74 69 6f 6e 20 |w;transc|ription |
|00001930| 66 61 63 74 6f 72 73 3b | 53 70 31 3b 70 6f 6c 20 |factors;|Sp1;pol |
|00001940| 49 49 3b 43 41 54 20 62 | 6f 78 3b 47 43 20 62 6f |II;CAT b|ox;GC bo|
|00001950| 78 3b 20 74 72 61 6e 73 | 2d 61 63 74 69 6e 67 20 |x; trans|-acting |
|00001960| 66 61 63 74 6f 72 73 3b | 67 65 6e 65 20 65 78 70 |factors;|gene exp|
|00001970| 72 65 73 73 69 6f 6e 3b | 70 72 6f 6d 6f 74 65 72 |ression;|promoter|
|00001980| 3b 65 75 6b 61 72 79 6f | 74 65 73 3b 00 07 1d 00 |;eukaryo|tes;....|
|00001990| 01 3c 31 05 03 08 05 02 | 01 01 00 00 54 68 65 20 |.<1.....|....The |
|000019a0| 74 6f 70 6f 6c 6f 67 79 | 20 6f 66 20 68 6f 6d 6f |topology| of homo|
|000019b0| 6c 6f 67 6f 75 73 20 70 | 61 69 72 69 6e 67 20 70 |logous p|airing p|
|000019c0| 72 6f 6d 6f 74 65 64 20 | 62 79 20 52 65 63 41 20 |romoted |by RecA |
|000019d0| 70 72 6f 74 65 69 6e 00 | 44 61 73 47 75 70 74 61 |protein.|DasGupta|
|000019e0| 20 43 2c 20 53 68 69 62 | 61 74 61 20 54 2c 20 43 | C, Shib|ata T, C|
|000019f0| 75 6e 6e 69 6e 67 68 61 | 6d 20 52 50 2c 20 52 61 |unningha|m RP, Ra|
|00001a00| 64 64 69 6e 67 20 43 4d | 00 43 65 6c 6c 00 32 32 |dding CM|.Cell.22|
|00001a10| 00 34 33 37 2d 34 34 36 | 00 31 39 38 30 00 4a 00 |.437-446|.1980.J.|
|00001a20| 00 00 4d 65 74 68 6f 64 | 73 3b 20 52 65 63 41 20 |..Method|s; RecA |
|00001a30| 70 72 6f 74 65 69 6e 3b | 20 48 6f 6d 6f 6c 6f 67 |protein;| Homolog|
|00001a40| 6f 75 73 20 50 61 69 72 | 69 6e 67 2f 52 65 63 6f |ous Pair|ing/Reco|
|00001a50| 6d 62 69 6e 61 74 69 6f | 6e 3b 20 44 4e 41 20 54 |mbinatio|n; DNA T|
|00001a60| 6f 70 6f 6c 6f 67 79 3b | 20 44 4e 41 20 53 74 72 |opology;| DNA Str|
|00001a70| 75 63 74 75 72 65 00 07 | 1e 00 01 48 09 05 03 08 |ucture..|...H....|
|00001a80| 05 02 01 01 00 00 54 68 | 65 20 72 6f 6c 65 20 6f |......Th|e role o|
|00001a90| 66 20 73 74 61 62 6c 65 | 20 63 6f 6d 70 6c 65 78 |f stable| complex|
|00001aa0| 65 73 20 74 68 61 74 20 | 72 65 70 72 65 73 73 20 |es that |repress |
|00001ab0| 61 6e 64 20 61 63 74 69 | 76 61 74 65 20 65 75 63 |and acti|vate euc|
|00001ac0| 61 72 79 6f 74 69 63 20 | 67 65 6e 65 73 00 42 72 |aryotic |genes.Br|
|00001ad0| 6f 77 6e 20 44 44 00 43 | 65 6c 6c 00 33 37 00 33 |own DD.C|ell.37.3|
|00001ae0| 35 39 2d 33 36 35 00 31 | 39 38 34 00 4a 00 00 00 |59-365.1|984.J...|
|00001af0| 52 65 76 69 65 77 3b 74 | 72 61 6e 73 63 72 69 70 |Review;t|ranscrip|
|00001b00| 74 69 6f 6e 20 66 61 63 | 74 6f 72 73 3b 52 4e 41 |tion fac|tors;RNA|
|00001b10| 20 70 6f 6c 20 49 49 49 | 3b 73 74 61 62 6c 65 20 | pol III|;stable |
|00001b20| 74 72 61 6e 73 63 72 69 | 70 74 69 6f 6e 20 63 6f |transcri|ption co|
|00001b30| 6d 70 6c 65 78 65 73 3b | 64 65 76 65 6c 6f 70 6d |mplexes;|developm|
|00001b40| 65 6e 74 61 6c 20 67 65 | 6e 65 20 65 78 70 72 65 |ental ge|ne expre|
|00001b50| 73 73 69 6f 6e 3b 74 72 | 61 6e 73 2d 61 63 74 69 |ssion;tr|ans-acti|
|00001b60| 6e 67 20 66 61 63 74 6f | 72 73 3b 63 6f 6d 6d 69 |ng facto|rs;commi|
|00001b70| 74 6d 65 6e 74 3b 00 07 | 1f 00 01 64 15 05 03 08 |tment;..|...d....|
|00001b80| 05 02 01 01 00 00 42 79 | 20 73 65 61 72 63 68 69 |......By| searchi|
|00001b90| 6e 67 20 70 72 6f 63 65 | 73 73 69 76 65 6c 79 20 |ng proce|ssively |
|00001ba0| 52 65 63 41 20 70 72 6f | 74 65 69 6e 20 70 61 69 |RecA pro|tein pai|
|00001bb0| 72 73 20 44 4e 41 20 6d | 6f 6c 65 63 75 6c 65 73 |rs DNA m|olecules|
|00001bc0| 20 74 68 61 74 20 73 68 | 61 72 65 20 61 20 6c 69 | that sh|are a li|
|00001bd0| 6d 69 74 65 64 20 73 74 | 72 65 74 63 68 20 6f 66 |mited st|retch of|
|00001be0| 20 68 6f 6d 6f 6c 6f 67 | 79 00 47 6f 6e 64 61 20 | homolog|y.Gonda |
|00001bf0| 44 4b 2c 20 52 61 64 64 | 69 6e 67 20 43 4d 00 43 |DK, Radd|ing CM.C|
|00001c00| 65 6c 6c 00 33 34 00 36 | 34 37 2d 36 35 34 00 31 |ell.34.6|47-654.1|
|00001c10| 39 38 33 00 4a 00 00 00 | 4d 65 74 68 6f 64 73 3b |983.J...|Methods;|
|00001c20| 20 52 65 63 41 20 70 72 | 6f 74 65 69 6e 3b 20 54 | RecA pr|otein; T|
|00001c30| 65 72 6e 65 72 79 20 43 | 6f 6d 70 6c 65 78 3b 20 |ernery C|omplex; |
|00001c40| 48 6f 6d 6f 6c 6f 67 6f | 75 73 20 50 61 69 72 69 |Homologo|us Pairi|
|00001c50| 6e 67 3b 20 48 6f 6d 6f | 6c 6f 67 79 20 53 69 7a |ng; Homo|logy Siz|
|00001c60| 65 3b 00 07 20 00 01 92 | 20 0c 04 0a 05 02 01 01 |e;.. ...| .......|
|00001c70| 00 00 4f 6e 20 74 68 65 | 20 6d 65 63 68 61 6e 69 |..On the| mechani|
|00001c80| 73 6d 20 6f 66 20 70 61 | 69 72 69 6e 67 20 6f 66 |sm of pa|iring of|
|00001c90| 20 73 69 6e 67 6c 65 2d | 20 61 6e 64 20 64 6f 75 | single-| and dou|
|00001ca0| 62 6c 65 2d 73 74 72 61 | 6e 64 65 64 20 44 4e 41 |ble-stra|nded DNA|
|00001cb0| 20 6d 6f 6c 65 63 75 6c | 65 73 20 62 79 20 74 68 | molecul|es by th|
|00001cc0| 65 20 52 65 63 41 20 61 | 6e 64 20 73 69 6e 67 6c |e RecA a|nd singl|
|00001cd0| 65 2d 73 74 72 61 6e 64 | 65 64 20 44 4e 41 2d 62 |e-strand|ed DNA-b|
|00001ce0| 69 6e 64 69 6e 67 20 70 | 72 6f 74 65 69 6e 73 20 |inding p|roteins |
|00001cf0| 6f 66 20 45 73 63 68 65 | 72 69 63 68 69 61 20 43 |of Esche|richia C|
|00001d00| 6f 6c 69 00 4a 75 6c 69 | 6e 20 44 41 2c 20 52 69 |oli.Juli|n DA, Ri|
|00001d10| 64 64 6c 65 73 20 50 57 | 2c 20 4c 65 68 6d 61 6e |ddles PW|, Lehman|
|00001d20| 20 49 52 00 4a 20 42 69 | 6f 6c 20 43 68 65 6d 00 | IR.J Bi|ol Chem.|
|00001d30| 32 36 31 00 31 30 32 35 | 2d 31 30 33 30 00 31 39 |261.1025|-1030.19|
|00001d40| 38 36 00 4a 00 00 00 4d | 65 74 68 6f 64 73 3b 20 |86.J...M|ethods; |
|00001d50| 52 65 63 41 20 50 72 6f | 74 65 69 6e 3b 20 53 53 |RecA Pro|tein; SS|
|00001d60| 42 20 70 72 6f 74 65 69 | 6e 3b 00 07 21 00 01 4f |B protei|n;..!..O|
|00001d70| 23 0f 0e 04 05 02 17 49 | 00 00 55 6e 63 6f 75 70 |#......I|..Uncoup|
|00001d80| 6c 69 6e 67 20 6f 66 20 | 6d 79 6f 74 75 62 65 20 |ling of |myotube |
|00001d90| 66 6f 72 6d 61 74 69 6f | 6e 20 61 6e 64 20 70 42 |formatio|n and pB|
|00001da0| 55 36 35 20 66 72 6f 6d | 20 6f 74 68 65 72 20 6d |U65 from| other m|
|00001db0| 75 73 63 6c 65 20 70 72 | 6f 74 65 69 6e 20 65 78 |uscle pr|otein ex|
|00001dc0| 70 72 65 73 73 69 6f 6e | 00 57 72 69 67 68 74 20 |pression|.Wright |
|00001dd0| 57 45 2c 20 43 6f 63 6b | 65 72 69 6c 6c 20 47 2c |WE, Cock|erill G,|
|00001de0| 20 4d 61 68 6d 6f 75 64 | 69 20 4d 00 4a 20 43 65 | Mahmoud|i M.J Ce|
|00001df0| 6c 6c 20 42 69 6f 63 68 | 65 6d 00 53 75 70 70 6c |ll Bioch|em.Suppl|
|00001e00| 65 6d 65 6e 74 20 31 32 | 00 33 38 39 00 31 39 38 |ement 12|.389.198|
|00001e10| 38 00 41 00 46 2e 20 53 | 74 6f 63 6b 64 61 6c 65 |8.A.F. S|tockdale|
|00001e20| 2c 20 4c 2e 20 4b 65 64 | 65 73 00 55 43 4c 41 20 |, L. Ked|es.UCLA |
|00001e30| 53 79 6d 70 6f 73 69 75 | 6d 20 6f 6e 20 74 68 65 |Symposiu|m on the|
|00001e40| 20 4d 6f 6c 65 63 75 6c | 61 72 20 26 20 43 65 6c | Molecul|ar & Cel|
|00001e50| 6c 75 6c 61 72 20 42 69 | 6f 6c 6f 67 79 20 6f 66 |lular Bi|ology of|
|00001e60| 20 4d 75 73 63 6c 65 20 | 44 65 76 65 6c 6f 70 6d | Muscle |Developm|
|00001e70| 65 6e 74 00 4d 79 6f 67 | 65 6e 65 73 69 73 3b 20 |ent.Myog|enesis; |
|00001e80| 70 42 55 36 35 2f 6d 64 | 66 31 3b 20 47 65 6e 65 |pBU65/md|f1; Gene|
|00001e90| 20 45 78 70 72 65 73 73 | 69 6f 6e 3b 20 44 65 76 | Express|ion; Dev|
|00001ea0| 65 6c 6f 70 6d 65 6e 74 | 3b 20 52 65 67 75 6c 61 |elopment|; Regula|
|00001eb0| 74 6f 72 79 20 46 61 63 | 74 6f 72 73 3b 00 07 22 |tory Fac|tors;.."|
|00001ec0| 00 01 63 29 0f 0e 04 05 | 02 17 4b 00 00 70 42 55 |..c)....|..K..pBU|
|00001ed0| 36 35 2c 20 61 6e 20 65 | 61 72 6c 79 20 66 61 63 |65, an e|arly fac|
|00001ee0| 74 6f 72 20 74 72 61 6e | 73 69 65 6e 74 6c 79 20 |tor tran|siently |
|00001ef0| 65 78 70 72 65 73 73 65 | 64 20 64 75 72 69 6e 67 |expresse|d during|
|00001f00| 20 6d 79 6f 67 65 6e 65 | 73 69 73 20 69 6e 20 63 | myogene|sis in c|
|00001f10| 75 6c 74 75 72 65 20 61 | 6e 64 20 69 6e 20 66 65 |ulture a|nd in fe|
|00001f20| 74 61 6c 20 64 65 76 65 | 6c 6f 70 6d 65 6e 74 00 |tal deve|lopment.|
|00001f30| 4c 69 6e 20 56 4b 2c 20 | 4d 69 72 61 6e 64 61 20 |Lin VK, |Miranda |
|00001f40| 4c 4d 2c 20 53 61 73 73 | 6f 6f 6e 20 44 2c 20 57 |LM, Sass|oon D, W|
|00001f50| 72 69 67 68 74 20 57 45 | 00 4a 20 43 65 6c 6c 20 |right WE|.J Cell |
|00001f60| 42 69 6f 63 68 65 6d 00 | 53 75 70 70 6c 65 6d 65 |Biochem.|Suppleme|
|00001f70| 6e 74 20 31 32 00 33 32 | 38 00 31 39 38 38 00 41 |nt 12.32|8.1988.A|
|00001f80| 00 46 2e 20 53 74 6f 63 | 6b 64 61 6c 65 2c 20 4c |.F. Stoc|kdale, L|
|00001f90| 2e 20 4b 65 64 65 73 00 | 55 43 4c 41 20 53 79 6d |. Kedes.|UCLA Sym|
|00001fa0| 70 6f 73 69 75 6d 20 6f | 6e 20 74 68 65 20 43 65 |posium o|n the Ce|
|00001fb0| 6c 6c 75 6c 61 72 20 61 | 6e 64 20 4d 6f 6c 65 63 |llular a|nd Molec|
|00001fc0| 75 6c 61 72 20 42 69 6f | 6c 6f 67 79 20 6f 66 20 |ular Bio|logy of |
|00001fd0| 4d 75 73 63 6c 65 20 44 | 65 76 65 6c 6f 70 6d 65 |Muscle D|evelopme|
|00001fe0| 6e 74 00 4d 79 6f 67 65 | 6e 65 73 69 73 3b 20 70 |nt.Myoge|nesis; p|
|00001ff0| 42 55 36 35 2f 6d 64 66 | 31 3b 20 52 65 67 75 6c |BU65/mdf|1; Regul|
|00002000| 61 74 6f 72 79 20 46 61 | 63 74 6f 72 73 3b 20 49 |atory Fa|ctors; I|
|00002010| 6e 20 73 69 74 75 20 48 | 79 62 72 69 64 69 7a 61 |n situ H|ybridiza|
|00002020| 74 69 6f 6e 3b 20 63 65 | 6c 6c 20 64 69 66 66 65 |tion; ce|ll diffe|
|00002030| 72 65 6e 74 69 61 74 69 | 6f 6e 3b 20 70 75 74 61 |rentiati|on; puta|
|00002040| 74 69 76 65 20 74 72 61 | 6e 73 2d 61 63 74 69 6e |tive tra|ns-actin|
|00002050| 67 20 66 61 63 74 6f 72 | 3b 00 07 23 00 01 24 15 |g factor|;..#..$.|
|00002060| 13 03 08 05 02 01 01 00 | 00 50 6f 69 73 69 6e 67 |........|.Poising|
|00002070| 20 63 68 72 6f 6d 61 74 | 69 6e 20 66 6f 72 20 74 | chromat|in for t|
|00002080| 72 61 6e 73 63 72 69 70 | 74 69 6f 6e 00 47 72 6f |ranscrip|tion.Gro|
|00002090| 73 73 20 44 53 2c 20 47 | 61 72 72 61 72 64 20 57 |ss DS, G|arrard W|
|000020a0| 54 00 54 72 65 6e 64 73 | 20 42 69 6f 63 68 65 6d |T.Trends| Biochem|
|000020b0| 20 53 63 69 00 31 32 00 | 32 39 33 2d 32 39 37 00 | Sci.12.|293-297.|
|000020c0| 31 39 38 37 00 4a 00 00 | 00 52 65 76 69 65 77 3b |1987.J..|.Review;|
|000020d0| 20 63 68 72 6f 6d 61 74 | 69 6e 3b 20 74 72 61 6e | chromat|in; tran|
|000020e0| 73 63 72 69 70 74 69 6f | 6e 20 63 6f 6d 70 6c 65 |scriptio|n comple|
|000020f0| 78 3b 20 68 69 73 74 6f | 6e 65 73 3b 20 6c 6f 6f |x; histo|nes; loo|
|00002100| 70 65 64 20 44 4e 41 3b | 20 63 69 73 20 26 20 74 |ped DNA;| cis & t|
|00002110| 72 61 6e 73 20 73 65 71 | 75 65 6e 63 65 73 3b 6e |rans seq|uences;n|
|00002120| 75 63 6c 65 6f 73 6f 6d | 65 73 3b 65 6e 68 61 6e |ucleosom|es;enhan|
|00002130| 63 65 72 73 20 66 75 6e | 63 74 69 6f 6e 3b 72 65 |cers fun|ction;re|
|00002140| 70 72 65 73 73 69 6f 6e | 3b 61 64 76 2e 20 43 26 |pression|;adv. C&|
|00002150| 4d 42 00 07 24 00 01 9c | 16 05 03 08 05 02 01 01 |MB..$...|........|
|00002160| 00 00 42 69 6e 64 69 6e | 67 20 6f 66 20 74 72 61 |..Bindin|g of tra|
|00002170| 6e 73 63 72 69 70 74 69 | 6f 6e 20 66 61 63 74 6f |nscripti|on facto|
|00002180| 72 20 54 46 49 49 44 20 | 74 6f 20 74 68 65 20 6d |r TFIID |to the m|
|00002190| 61 6a 6f 72 20 6c 61 74 | 65 20 70 72 6f 6d 6f 74 |ajor lat|e promot|
|000021a0| 65 72 20 64 75 72 69 6e | 67 20 69 6e 20 76 69 74 |er durin|g in vit|
|000021b0| 72 6f 20 6e 75 63 6c 65 | 6f 73 6f 6d 65 20 61 73 |ro nucle|osome as|
|000021c0| 73 65 6d 62 6c 79 20 70 | 6f 74 65 6e 74 69 61 74 |sembly p|otentiat|
|000021d0| 65 73 20 73 75 62 73 65 | 71 75 65 6e 74 20 69 6e |es subse|quent in|
|000021e0| 69 74 69 61 74 69 6f 6e | 20 62 79 20 52 4e 41 20 |itiation| by RNA |
|000021f0| 70 6f 6c 79 6d 65 72 61 | 73 65 20 49 49 00 57 6f |polymera|se II.Wo|
|00002200| 72 6b 6d 61 6e 20 4a 4c | 2c 20 52 6f 65 64 65 72 |rkman JL|, Roeder|
|00002210| 20 52 47 00 43 65 6c 6c | 00 35 31 00 36 31 33 2d | RG.Cell|.51.613-|
|00002220| 36 32 32 00 31 39 38 37 | 00 4a 00 00 00 41 64 76 |622.1987|.J...Adv|
|00002230| 2e 43 26 4d 42 3b 54 46 | 49 49 44 3b 74 72 61 6e |.C&MB;TF|IID;tran|
|00002240| 73 63 72 69 70 74 69 6f | 6e 20 66 61 63 74 6f 72 |scriptio|n factor|
|00002250| 73 3b 74 72 61 6e 73 2d | 61 63 74 69 6e 67 20 66 |s;trans-|acting f|
|00002260| 61 63 74 6f 72 73 3b 68 | 75 6d 61 6e 3b 20 54 41 |actors;h|uman; TA|
|00002270| 54 41 20 62 6f 78 20 62 | 69 6e 64 69 6e 67 20 66 |TA box b|inding f|
|00002280| 61 63 74 6f 72 3b 6e 75 | 63 6c 65 6f 73 6f 6d 65 |actor;nu|cleosome|
|00002290| 73 3b 74 72 61 6e 73 63 | 72 69 70 74 69 6f 6e 20 |s;transc|ription |
|000022a0| 63 6f 6d 70 6c 65 78 3b | 54 46 49 49 45 3b 58 65 |complex;|TFIIE;Xe|
|000022b0| 6e 6f 70 75 73 3b 48 65 | 4c 61 00 07 25 00 01 70 |nopus;He|La..%..p|
|000022c0| 1a 05 03 0a 05 02 01 01 | 00 00 44 69 73 74 69 6e |........|..Distin|
|000022d0| 67 75 69 73 68 69 6e 67 | 20 62 65 74 77 65 65 6e |guishing| between|
|000022e0| 20 6d 65 63 68 61 6e 69 | 73 6d 73 20 6f 66 20 65 | mechani|sms of e|
|000022f0| 75 6b 61 72 79 6f 74 69 | 63 20 74 72 61 6e 73 63 |ukaryoti|c transc|
|00002300| 72 69 70 74 69 6f 6e 61 | 6c 20 61 63 74 69 76 61 |riptiona|l activa|
|00002310| 74 69 6f 6e 20 77 69 74 | 68 20 62 61 63 74 65 72 |tion wit|h bacter|
|00002320| 69 6f 70 68 61 67 65 20 | 54 37 20 52 4e 41 20 70 |iophage |T7 RNA p|
|00002330| 6f 6c 79 6d 65 72 61 73 | 65 00 43 68 65 6e 20 57 |olymeras|e.Chen W|
|00002340| 2c 20 54 61 62 6f 72 20 | 53 2c 20 53 74 72 75 68 |, Tabor |S, Struh|
|00002350| 6c 20 4b 00 43 65 6c 6c | 00 35 30 00 31 30 34 37 |l K.Cell|.50.1047|
|00002360| 2d 31 30 35 35 00 31 39 | 38 37 00 4a 00 00 00 41 |-1055.19|87.J...A|
|00002370| 64 76 2e 43 26 4d 42 3b | 54 37 20 52 4e 41 20 70 |dv.C&MB;|T7 RNA p|
|00002380| 6f 6c 79 6d 65 72 61 73 | 65 3b 79 65 61 73 74 3b |olymeras|e;yeast;|
|00002390| 67 61 6c 34 3b 64 65 64 | 31 3b 68 69 73 33 3b 74 |gal4;ded|1;his3;t|
|000023a0| 72 61 6e 73 63 72 69 70 | 74 69 6f 6e 3b 20 74 72 |ranscrip|tion; tr|
|000023b0| 61 6e 73 2d 61 63 74 69 | 6e 67 20 66 61 63 74 6f |ans-acti|ng facto|
|000023c0| 72 73 3b 55 41 53 3b 65 | 6e 68 61 6e 63 65 72 20 |rs;UAS;e|nhancer |
|000023d0| 66 75 6e 63 74 69 6f 6e | 3b 6d 65 63 68 61 6e 69 |function|;mechani|
|000023e0| 73 6d 73 3b 00 07 26 00 | 01 4b 1c 05 03 08 05 02 |sms;..&.|.K......|
|000023f0| 01 01 00 00 54 68 65 20 | 75 73 65 20 6f 66 20 70 |....The |use of p|
|00002400| 73 6f 72 61 6c 65 6e 2d | 6d 6f 64 69 66 69 65 64 |soralen-|modified|
|00002410| 20 44 4e 41 20 74 6f 20 | 70 72 6f 62 65 20 74 68 | DNA to |probe th|
|00002420| 65 20 6d 65 63 68 61 6e | 69 73 6d 20 6f 66 20 65 |e mechan|ism of e|
|00002430| 6e 68 61 6e 63 65 72 20 | 61 63 74 69 6f 6e 00 43 |nhancer |action.C|
|00002440| 6f 75 72 65 79 20 41 4a | 2c 20 50 6c 6f 6e 20 53 |ourey AJ|, Plon S|
|00002450| 45 2c 20 57 61 6e 67 20 | 4a 43 00 43 65 6c 6c 00 |E, Wang |JC.Cell.|
|00002460| 34 35 00 35 36 37 2d 35 | 37 34 00 31 39 38 35 00 |45.567-5|74.1985.|
|00002470| 4a 00 00 00 41 64 76 2e | 43 26 4d 42 3b 53 56 34 |J...Adv.|C&MB;SV4|
|00002480| 30 3b 65 6e 68 61 6e 63 | 65 72 3b 68 75 6d 61 6e |0;enhanc|er;human|
|00002490| 3b 20 62 65 74 61 2d 67 | 6c 6f 62 69 6e 3b 70 73 |; beta-g|lobin;ps|
|000024a0| 6f 72 61 6c 65 6e 20 61 | 64 64 75 63 74 73 3b 20 |oralen a|dducts; |
|000024b0| 6d 65 63 68 61 6e 69 73 | 6d 3b 74 72 61 6e 73 2d |mechanis|m;trans-|
|000024c0| 61 63 74 69 6e 67 20 66 | 61 63 74 6f 72 73 3b 00 |acting f|actors;.|
|000024d0| 07 27 00 01 8c 13 05 03 | 08 05 02 01 01 00 00 53 |.'......|.......S|
|000024e0| 56 34 30 20 65 6e 68 61 | 6e 63 65 72 2d 62 69 6e |V40 enha|ncer-bin|
|000024f0| 64 69 6e 67 20 66 61 63 | 74 6f 72 73 20 61 72 65 |ding fac|tors are|
|00002500| 20 72 65 71 75 69 72 65 | 64 20 61 74 20 74 68 65 | require|d at the|
|00002510| 20 65 73 74 61 62 6c 69 | 73 68 6d 65 6e 74 20 62 | establi|shment b|
|00002520| 75 74 20 6e 6f 74 20 74 | 68 65 20 6d 61 69 6e 74 |ut not t|he maint|
|00002530| 65 6e 61 6e 63 65 20 73 | 74 65 70 20 6f 66 20 65 |enance s|tep of e|
|00002540| 6e 68 61 6e 63 65 72 2d | 64 65 70 65 6e 64 65 6e |nhancer-|dependen|
|00002550| 74 20 74 72 61 6e 73 63 | 72 69 70 74 69 6f 6e 20 |t transc|ription |
|00002560| 61 63 74 69 76 61 74 69 | 6f 6e 00 57 61 6e 67 20 |activati|on.Wang |
|00002570| 58 2d 46 2c 20 43 61 6c | 61 6d 65 20 4a 00 43 65 |X-F, Cal|ame J.Ce|
|00002580| 6c 6c 00 34 37 00 32 34 | 31 2d 32 34 37 00 31 39 |ll.47.24|1-247.19|
|00002590| 38 36 00 4a 00 00 00 41 | 64 76 2e 43 26 4d 42 3b |86.J...A|dv.C&MB;|
|000025a0| 53 56 34 30 20 65 6e 68 | 61 6e 63 65 72 3b 43 4f |SV40 enh|ancer;CO|
|000025b0| 53 20 63 65 6c 6c 73 3b | 74 72 61 6e 73 2d 61 63 |S cells;|trans-ac|
|000025c0| 74 69 6e 67 20 66 61 63 | 74 6f 72 73 3b 20 65 73 |ting fac|tors; es|
|000025d0| 74 61 62 6c 69 73 68 6d | 65 6e 74 2f 6d 61 69 6e |tablishm|ent/main|
|000025e0| 74 65 6e 61 6e 63 65 3b | 74 72 61 6e 73 63 72 69 |tenance;|transcri|
|000025f0| 70 74 69 6f 6e 20 63 6f | 6d 70 6c 65 78 3b 00 07 |ption co|mplex;..|
|00002600| 28 00 01 3c 0a 07 04 08 | 05 02 01 01 00 00 47 65 |(..<....|......Ge|
|00002610| 6e 65 20 72 65 67 75 6c | 61 74 69 6f 6e 20 62 79 |ne regul|ation by|
|00002620| 20 70 72 6f 74 65 69 6e | 73 20 61 63 74 69 6e 67 | protein|s acting|
|00002630| 20 6e 65 61 72 62 79 20 | 61 6e 64 20 61 74 20 61 | nearby |and at a|
|00002640| 20 64 69 73 74 61 6e 63 | 65 00 50 74 61 73 68 6e | distanc|e.Ptashn|
|00002650| 65 20 4d 00 4e 61 74 75 | 72 65 00 33 32 32 00 36 |e M.Natu|re.322.6|
|00002660| 39 37 2d 37 30 31 00 31 | 39 38 36 00 4a 00 00 00 |97-701.1|986.J...|
|00002670| 41 64 76 2e 43 26 4d 42 | 3b 52 65 76 69 65 77 3b |Adv.C&MB|;Review;|
|00002680| 74 72 61 6e 73 63 72 69 | 70 74 69 6f 6e 20 72 65 |transcri|ption re|
|00002690| 67 75 6c 61 74 69 6f 6e | 3b 74 72 61 6e 73 2d 61 |gulation|;trans-a|
|000026a0| 63 74 69 6e 67 20 66 61 | 63 74 6f 72 73 3b 20 65 |cting fa|ctors; e|
|000026b0| 6e 68 61 6e 63 65 72 3b | 44 4e 41 20 6c 6f 6f 70 |nhancer;|DNA loop|
|000026c0| 69 6e 67 3b 6d 65 63 68 | 61 6e 69 73 6d 3b 74 77 |ing;mech|anism;tw|
|000026d0| 69 73 74 69 6e 67 3b 73 | 6c 69 64 69 6e 67 3b 6f |isting;s|liding;o|
|000026e0| 6f 7a 69 6e 67 3b 00 07 | 29 00 01 3c 24 08 04 0a |ozing;..|)..<$...|
|000026f0| 05 02 01 01 00 00 52 65 | 67 75 6c 61 74 69 6f 6e |......Re|gulation|
|00002700| 20 6f 66 20 69 6e 64 75 | 63 69 62 6c 65 20 61 6e | of indu|cible an|
|00002710| 64 20 74 69 73 73 75 65 | 2d 73 70 65 63 69 66 69 |d tissue|-specifi|
|00002720| 63 20 67 65 6e 65 20 65 | 78 70 72 65 73 73 69 6f |c gene e|xpressio|
|00002730| 6e 00 4d 61 6e 69 61 74 | 69 73 20 54 2c 20 47 6f |n.Maniat|is T, Go|
|00002740| 6f 64 62 6f 75 72 6e 20 | 53 2c 20 46 69 73 63 68 |odbourn |S, Fisch|
|00002750| 65 72 20 4a 41 00 53 63 | 69 65 6e 63 65 00 32 33 |er JA.Sc|ience.23|
|00002760| 36 00 31 32 33 37 2d 31 | 32 34 35 00 31 39 38 37 |6.1237-1|245.1987|
|00002770| 00 4a 00 00 00 41 64 76 | 2e 43 26 4d 42 3b 52 65 |.J...Adv|.C&MB;Re|
|00002780| 76 69 65 77 3b 74 69 73 | 73 75 65 2d 73 70 65 63 |view;tis|sue-spec|
|00002790| 69 66 69 63 20 67 65 6e | 65 20 65 78 70 72 65 73 |ific gen|e expres|
|000027a0| 73 69 6f 6e 3b 69 6e 64 | 75 63 69 62 6c 65 20 67 |sion;ind|ucible g|
|000027b0| 65 6e 65 73 3b 20 74 72 | 61 6e 73 2d 61 63 74 69 |enes; tr|ans-acti|
|000027c0| 6e 67 20 66 61 63 74 6f | 72 73 3b 63 69 73 2d 61 |ng facto|rs;cis-a|
|000027d0| 63 74 69 6e 67 20 65 6c | 65 6d 65 6e 74 73 3b 00 |cting el|ements;.|
|000027e0| 07 2a 00 01 4a 13 07 04 | 08 05 02 01 01 00 00 43 |.*..J...|.......C|
|000027f0| 61 72 63 69 6e 6f 67 65 | 6e 65 73 69 73 3a 20 20 |arcinoge|nesis:  |
|00002800| 41 20 73 75 70 65 72 66 | 61 6d 69 6c 79 20 6f 66 |A superf|amily of|
|00002810| 20 70 6f 74 65 6e 74 69 | 61 6c 6c 79 20 6f 6e 63 | potenti|ally onc|
|00002820| 6f 67 65 6e 69 63 20 68 | 6f 72 6d 6f 6e 65 20 72 |ogenic h|ormone r|
|00002830| 65 63 65 70 74 6f 72 73 | 00 47 72 65 65 6e 20 53 |eceptors|.Green S|
|00002840| 2c 20 43 68 61 6d 62 6f | 6e 20 50 00 4e 61 74 75 |, Chambo|n P.Natu|
|00002850| 72 65 00 33 32 34 00 36 | 31 35 2d 36 31 37 00 31 |re.324.6|15-617.1|
|00002860| 39 38 36 00 4a 00 00 00 | 4e 65 77 73 20 26 20 56 |986.J...|News & V|
|00002870| 69 65 77 73 3b 41 64 76 | 2e 43 26 4d 42 3b 4d 69 |iews;Adv|.C&MB;Mi|
|00002880| 6e 69 2d 52 65 76 69 65 | 77 3b 68 6f 72 6d 6f 6e |ni-Revie|w;hormon|
|00002890| 65 20 72 65 63 65 70 74 | 6f 72 73 3b 67 6c 75 63 |e recept|ors;gluc|
|000028a0| 6f 63 6f 72 74 69 63 6f | 69 64 20 3b 7a 69 6e 63 |ocortico|id ;zinc|
|000028b0| 20 66 69 6e 67 65 72 73 | 3b 65 73 74 72 6f 67 65 | fingers|;estroge|
|000028c0| 6e 3b 65 72 62 2d 41 20 | 6f 6e 63 6f 67 65 6e 65 |n;erb-A |oncogene|
|000028d0| 3b 74 68 79 72 6f 69 64 | 20 68 6f 72 6d 6f 6e 65 |;thyroid| hormone|
|000028e0| 3b 00 07 2b 00 01 68 25 | 07 02 0a 05 02 01 01 00 |;..+..h%|........|
|000028f0| 00 4c 6f 63 61 6c 69 73 | 61 74 69 6f 6e 20 6f 66 |.Localis|ation of|
|00002900| 20 74 68 65 20 6f 65 73 | 74 72 61 64 69 6f 6c 2d | the oes|tradiol-|
|00002910| 62 69 6e 64 69 6e 67 20 | 61 6e 64 20 70 75 74 61 |binding |and puta|
|00002920| 74 69 76 65 20 44 4e 41 | 2d 62 69 6e 64 69 6e 67 |tive DNA|-binding|
|00002930| 20 64 6f 6d 61 69 6e 73 | 20 6f 66 20 74 68 65 20 | domains| of the |
|00002940| 68 75 6d 61 6e 20 6f 65 | 73 74 72 6f 67 65 6e 20 |human oe|strogen |
|00002950| 72 65 63 65 70 74 6f 72 | 00 4b 75 6d 61 72 20 56 |receptor|.Kumar V|
|00002960| 2c 20 47 72 65 65 6e 20 | 53 2c 20 53 74 61 75 62 |, Green |S, Staub|
|00002970| 20 41 2c 20 43 68 61 6d | 62 6f 6e 20 50 00 45 4d | A, Cham|bon P.EM|
|00002980| 42 4f 20 4a 00 35 00 32 | 32 33 31 2d 32 32 33 36 |BO J.5.2|231-2236|
|00002990| 00 31 39 38 36 00 4a 00 | 00 00 41 64 76 2e 43 26 |.1986.J.|..Adv.C&|
|000029a0| 4d 42 3b 65 73 74 72 6f | 67 65 6e 20 72 65 63 65 |MB;estro|gen rece|
|000029b0| 70 74 6f 72 3b 44 4e 41 | 2d 62 69 6e 64 69 6e 67 |ptor;DNA|-binding|
|000029c0| 20 64 6f 6d 61 69 6e 73 | 3b 64 65 6c 65 74 69 6f | domains|;deletio|
|000029d0| 6e 20 61 6e 61 6c 79 73 | 69 73 3b 20 6d 65 74 68 |n analys|is; meth|
|000029e0| 6f 64 73 3b 73 69 74 65 | 2d 64 69 72 65 63 74 65 |ods;site|-directe|
|000029f0| 64 20 6d 75 74 61 67 65 | 6e 65 73 69 73 3b 48 65 |d mutage|nesis;He|
|00002a00| 4c 61 3b 68 75 6d 61 6e | 3b 63 68 69 63 6b 65 6e |La;human|;chicken|
|00002a10| 3b 7a 69 6e 63 2d 66 69 | 6e 67 65 72 73 3b 00 07 |;zinc-fi|ngers;..|
|00002a20| 2c 00 01 51 13 07 04 06 | 05 02 01 01 00 00 4f 65 |,..Q....|......Oe|
|00002a30| 73 74 72 61 64 69 6f 6c | 20 69 6e 64 75 63 74 69 |stradiol| inducti|
|00002a40| 6f 6e 20 6f 66 20 61 20 | 67 6c 75 63 6f 63 6f 72 |on of a |glucocor|
|00002a50| 74 69 63 6f 69 64 2d 72 | 65 73 70 6f 6e 73 69 76 |ticoid-r|esponsiv|
|00002a60| 65 20 67 65 6e 65 20 62 | 79 20 61 20 63 68 69 6d |e gene b|y a chim|
|00002a70| 61 65 72 69 63 20 72 65 | 63 65 70 74 6f 72 00 47 |aeric re|ceptor.G|
|00002a80| 72 65 65 6e 20 53 2c 20 | 43 68 61 6d 62 6f 6e 20 |reen S, |Chambon |
|00002a90| 50 00 4e 61 74 75 72 65 | 00 33 32 35 00 37 35 2d |P.Nature|.325.75-|
|00002aa0| 37 38 00 31 39 38 36 00 | 4a 00 00 00 63 68 69 6d |78.1986.|J...chim|
|00002ab0| 65 72 69 63 20 72 65 63 | 65 70 74 6f 72 3b 20 44 |eric rec|eptor; D|
|00002ac0| 4e 41 2d 62 69 6e 64 69 | 6e 67 20 70 72 6f 74 65 |NA-bindi|ng prote|
|00002ad0| 69 6e 3b 20 74 72 61 6e | 73 63 72 69 70 74 69 6f |in; tran|scriptio|
|00002ae0| 6e 3b 41 64 76 2e 43 26 | 4d 42 3b 20 73 74 65 72 |n;Adv.C&|MB; ster|
|00002af0| 6f 69 64 20 68 6f 72 6d | 6f 6e 65 20 72 65 63 65 |oid horm|one rece|
|00002b00| 70 74 6f 72 73 3b 7a 69 | 6e 63 2d 66 69 6e 67 65 |ptors;zi|nc-finge|
|00002b10| 72 73 3b 67 6c 75 63 6f | 63 6f 72 74 69 63 6f 69 |rs;gluco|corticoi|
|00002b20| 64 3b 64 6f 6d 61 69 6e | 73 3b 68 75 6d 61 6e 3b |d;domain|s;human;|
|00002b30| 63 68 69 63 6b 65 6e 00 | 07 2d 00 01 6e 30 05 03 |chicken.|.-..n0..|
|00002b40| 08 05 02 01 01 00 00 54 | 68 65 20 79 65 61 73 74 |.......T|he yeast|
|00002b50| 20 55 41 53 2d 47 20 69 | 73 20 61 20 74 72 61 6e | UAS-G i|s a tran|
|00002b60| 73 63 72 69 70 74 69 6f | 6e 61 6c 20 65 6e 68 61 |scriptio|nal enha|
|00002b70| 6e 63 65 72 20 69 6e 20 | 68 75 6d 61 6e 20 48 65 |ncer in |human He|
|00002b80| 4c 61 20 63 65 6c 6c 73 | 20 69 6e 20 74 68 65 20 |La cells| in the |
|00002b90| 70 72 65 73 65 6e 63 65 | 20 6f 66 20 74 68 65 20 |presence| of the |
|00002ba0| 47 41 4c 34 20 74 72 61 | 6e 73 2d 61 63 74 69 76 |GAL4 tra|ns-activ|
|00002bb0| 61 74 6f 72 00 57 65 62 | 73 74 65 72 20 4e 2c 20 |ator.Web|ster N, |
|00002bc0| 4a 69 6e 20 4a 52 2c 20 | 47 72 65 65 6e 20 53 2c |Jin JR, |Green S,|
|00002bd0| 20 48 6f 6c 6c 69 73 20 | 4d 2c 20 43 68 61 6d 62 | Hollis |M, Chamb|
|00002be0| 6f 6e 20 50 00 43 65 6c | 6c 00 35 32 00 31 36 39 |on P.Cel|l.52.169|
|00002bf0| 2d 31 37 38 00 31 39 38 | 38 00 4a 00 00 00 41 64 |-178.198|8.J...Ad|
|00002c00| 76 2e 43 26 4d 42 3b 55 | 41 53 3b 79 65 61 73 74 |v.C&MB;U|AS;yeast|
|00002c10| 3b 74 72 61 6e 73 63 72 | 69 70 74 69 6f 6e 20 72 |;transcr|iption r|
|00002c20| 65 67 75 6c 61 74 69 6f | 6e 3b 65 6e 68 61 6e 63 |egulatio|n;enhanc|
|00002c30| 65 72 3b 48 65 4c 61 20 | 63 65 6c 6c 73 3b 20 74 |er;HeLa |cells; t|
|00002c40| 72 61 6e 73 2d 61 63 74 | 69 6e 67 20 66 61 63 74 |rans-act|ing fact|
|00002c50| 6f 72 73 3b 53 56 34 30 | 20 65 6e 68 61 6e 63 65 |ors;SV40| enhance|
|00002c60| 72 3b 47 41 4c 34 3b 54 | 41 54 41 20 62 6f 78 3b |r;GAL4;T|ATA box;|
|00002c70| 68 75 6d 61 6e 20 65 73 | 74 72 6f 67 65 6e 20 72 |human es|trogen r|
|00002c80| 65 63 65 70 74 6f 72 00 | 07 2e 00 01 37 1c 05 03 |eceptor.|....7...|
|00002c90| 08 05 02 01 01 00 00 44 | 4e 41 2d 62 6f 75 6e 64 |.......D|NA-bound|
|00002ca0| 20 66 6f 73 20 70 72 6f | 74 65 69 6e 73 20 61 63 | fos pro|teins ac|
|00002cb0| 74 69 76 61 74 65 20 74 | 72 61 6e 73 63 72 69 70 |tivate t|ranscrip|
|00002cc0| 74 69 6f 6e 20 69 6e 20 | 79 65 61 73 74 00 4c 65 |tion in |yeast.Le|
|00002cd0| 63 68 20 4b 2c 20 41 6e | 64 65 72 73 6f 6e 20 4b |ch K, An|derson K|
|00002ce0| 2c 20 42 72 65 6e 74 20 | 52 00 43 65 6c 6c 00 35 |, Brent |R.Cell.5|
|00002cf0| 32 00 31 37 39 2d 31 38 | 34 00 31 39 38 38 00 4a |2.179-18|4.1988.J|
|00002d00| 00 00 00 41 64 76 2e 43 | 26 4d 42 3b 79 65 61 73 |...Adv.C|&MB;yeas|
|00002d10| 74 3b 46 6f 73 20 70 72 | 6f 74 65 69 6e 3b 4c 65 |t;Fos pr|otein;Le|
|00002d20| 78 41 20 72 65 70 72 65 | 73 73 6f 72 3b 6f 6e 63 |xA repre|ssor;onc|
|00002d30| 6f 67 65 6e 65 3b 6d 79 | 63 3b 4d 41 54 61 6c 70 |ogene;my|c;MATalp|
|00002d40| 68 61 32 3b 20 6d 65 63 | 68 61 6e 69 73 6d 73 3b |ha2; mec|hanisms;|
|00002d50| 70 68 6f 73 70 68 6f 72 | 79 6c 61 74 69 6f 6e 3b |phosphor|ylation;|
|00002d60| 74 72 61 6e 73 2d 61 63 | 74 69 6e 67 20 66 61 63 |trans-ac|ting fac|
|00002d70| 74 6f 72 73 3b 70 72 6f | 6d 6f 74 65 72 2f 65 6e |tors;pro|moter/en|
|00002d80| 68 61 6e 63 65 72 3b 55 | 41 53 3b 00 07 2f 00 01 |hancer;U|AS;../..|
|00002d90| 37 0a 10 03 08 05 02 04 | 29 00 00 47 20 70 72 6f |7.......|)..G pro|
|00002da0| 74 65 69 6e 73 3a 20 20 | 54 72 61 6e 73 64 75 63 |teins:  |Transduc|
|00002db0| 65 72 73 20 6f 66 20 72 | 65 63 65 70 74 6f 72 2d |ers of r|eceptor-|
|00002dc0| 67 65 6e 65 72 61 74 65 | 64 20 73 69 67 6e 61 6c |generate|d signal|
|00002dd0| 73 00 47 69 6c 6d 61 6e | 20 41 47 00 41 6e 6e 20 |s.Gilman| AG.Ann |
|00002de0| 52 65 76 20 42 69 6f 63 | 68 65 6d 00 35 36 00 36 |Rev Bioc|hem.56.6|
|00002df0| 31 35 2d 36 34 39 00 31 | 39 38 37 00 42 00 3f 3f |15-649.1|987.B.??|
|00002e00| 3f 00 41 6e 6e 75 61 6c | 20 52 65 76 69 65 77 73 |?.Annual| Reviews|
|00002e10| 2c 20 49 6e 63 2e 2c 20 | 50 61 6c 6f 20 41 6c 74 |, Inc., |Palo Alt|
|00002e20| 6f 2c 20 43 41 20 20 55 | 53 41 00 52 65 76 69 65 |o, CA  U|SA.Revie|
|00002e30| 77 3b 20 47 20 70 72 6f | 74 65 69 6e 73 3b 20 72 |w; G pro|teins; r|
|00002e40| 65 63 65 70 74 6f 72 73 | 3b 20 73 69 67 6e 61 6c |eceptors|; signal|
|00002e50| 20 74 72 61 6e 73 64 75 | 63 74 69 6f 6e 3b 20 70 | transdu|ction; p|
|00002e60| 72 6f 74 65 69 6e 2d 70 | 72 6f 74 65 69 6e 20 69 |rotein-p|rotein i|
|00002e70| 6e 74 65 72 61 63 74 69 | 6f 6e 73 3b 00 07 30 00 |nteracti|ons;..0.|
|00002e80| 01 61 78 08 04 08 05 02 | 01 01 00 00 41 70 6f 6c |.ax.....|....Apol|
|00002e90| 69 70 6f 70 72 6f 74 65 | 69 6e 20 42 2d 34 38 20 |ipoprote|in B-48 |
|00002ea0| 69 73 20 74 68 65 20 70 | 72 6f 64 75 63 74 20 6f |is the p|roduct o|
|00002eb0| 66 20 61 20 6d 65 73 73 | 65 6e 67 65 72 20 52 4e |f a mess|enger RN|
|00002ec0| 41 20 77 69 74 68 20 61 | 6e 20 6f 72 67 61 6e 2d |A with a|n organ-|
|00002ed0| 73 70 65 63 69 66 69 63 | 20 69 6e 2d 66 72 61 6d |specific| in-fram|
|00002ee0| 65 20 73 74 6f 70 20 63 | 6f 64 6f 6e 00 43 68 65 |e stop c|odon.Che|
|00002ef0| 6e 20 53 2d 48 2c 20 48 | 61 62 69 62 20 47 2c 20 |n S-H, H|abib G, |
|00002f00| 59 61 6e 67 20 43 2d 59 | 2c 20 47 75 20 5a 2d 57 |Yang C-Y|, Gu Z-W|
|00002f10| 2c 20 4c 65 65 20 42 52 | 2c 20 57 65 6e 67 20 53 |, Lee BR|, Weng S|
|00002f20| 2d 41 2c 20 53 69 6c 62 | 65 72 6d 61 6e 20 53 52 |-A, Silb|erman SR|
|00002f30| 2c 20 43 61 69 20 53 2d | 4a 2c 20 44 65 73 6c 79 |, Cai S-|J, Desly|
|00002f40| 70 65 72 65 20 4a 50 2c | 20 52 6f 73 73 65 6e 65 |pere JP,| Rossene|
|00002f50| 75 20 4d 2c 20 47 6f 74 | 74 6f 20 41 4d 2c 20 61 |u M, Got|to AM, a|
|00002f60| 6c 20 65 74 00 53 63 69 | 65 6e 63 65 00 32 33 38 |l et.Sci|ence.238|
|00002f70| 00 33 36 33 2d 33 36 36 | 00 31 39 38 37 00 4a 00 |.363-366|.1987.J.|
|00002f80| 00 00 47 65 6e 65 20 65 | 78 70 72 65 73 73 69 6f |..Gene e|xpressio|
|00002f90| 6e 3b 20 61 6c 74 65 72 | 6e 61 74 65 20 73 74 6f |n; alter|nate sto|
|00002fa0| 70 20 63 6f 64 6f 6e 20 | 75 73 61 67 65 3b 20 52 |p codon |usage; R|
|00002fb0| 4e 41 20 70 72 6f 63 65 | 73 73 69 6e 67 3b 20 74 |NA proce|ssing; t|
|00002fc0| 69 73 73 75 65 2d 73 70 | 65 63 69 66 69 63 20 67 |issue-sp|ecific g|
|00002fd0| 65 6e 65 20 65 78 70 72 | 65 73 73 69 6f 6e 3b 20 |ene expr|ession; |
|00002fe0| 4c 44 4c 3b 20 69 6e 74 | 65 73 74 69 6e 65 3b 00 |LDL; int|estine;.|
|00002ff0| 07 31 00 01 48 2c 08 04 | 08 05 02 01 01 00 00 43 |.1..H,..|.......C|
|00003000| 6f 6e 73 65 72 76 61 74 | 69 6f 6e 20 6f 66 20 74 |onservat|ion of t|
|00003010| 68 65 20 44 75 63 68 65 | 6e 6e 65 20 4d 75 73 63 |he Duche|nne Musc|
|00003020| 75 6c 61 72 20 44 79 73 | 74 72 6f 70 68 79 20 67 |ular Dys|trophy g|
|00003030| 65 6e 65 20 69 6e 20 6d | 69 63 65 20 61 6e 64 20 |ene in m|ice and |
|00003040| 68 75 6d 61 6e 73 00 48 | 6f 66 66 6d 61 6e 20 45 |humans.H|offman E|
|00003050| 50 2c 20 4d 6f 6e 61 63 | 6f 20 41 50 2c 20 46 65 |P, Monac|o AP, Fe|
|00003060| 65 6e 65 72 20 43 43 2c | 20 4b 75 6e 6b 65 6c 20 |ener CC,| Kunkel |
|00003070| 4c 4d 00 53 63 69 65 6e | 63 65 00 32 33 38 00 33 |LM.Scien|ce.238.3|
|00003080| 34 37 2d 33 35 30 00 31 | 39 38 37 00 4a 00 00 00 |47-350.1|987.J...|
|00003090| 44 4d 44 3b 20 44 75 63 | 68 65 6e 6e 65 20 4d 75 |DMD; Duc|henne Mu|
|000030a0| 73 63 75 6c 61 72 20 44 | 79 73 74 72 6f 70 68 79 |scular D|ystrophy|
|000030b0| 3b 20 67 65 6e 65 20 63 | 6f 6e 73 65 72 76 61 74 |; gene c|onservat|
|000030c0| 69 6f 6e 2f 68 6f 6d 6f | 6c 6f 67 79 3b 20 6d 75 |ion/homo|logy; mu|
|000030d0| 73 63 6c 65 20 64 69 73 | 65 61 73 65 73 3b 20 6d |scle dis|eases; m|
|000030e0| 79 6f 74 75 62 65 3b 20 | 72 65 67 65 6e 65 72 61 |yotube; |regenera|
|000030f0| 74 69 6f 6e 3b 00 07 32 | 00 01 61 37 05 03 08 05 |tion;..2|..a7....|
|00003100| 02 01 01 00 00 44 65 76 | 65 6c 6f 70 6d 65 6e 74 |.....Dev|elopment|
|00003110| 61 6c 20 70 61 74 74 65 | 72 6e 20 6f 66 20 6d 6f |al patte|rn of mo|
|00003120| 75 73 65 20 73 6b 65 6c | 65 74 61 6c 20 6d 79 6f |use skel|etal myo|
|00003130| 73 69 6e 20 68 65 61 76 | 79 20 63 68 61 69 6e 20 |sin heav|y chain |
|00003140| 67 65 6e 65 20 74 72 61 | 6e 73 63 72 69 70 74 73 |gene tra|nscripts|
|00003150| 20 69 6e 20 76 69 76 6f | 20 61 6e 64 20 69 6e 20 | in vivo| and in |
|00003160| 76 69 74 72 6f 00 57 65 | 79 64 65 72 74 20 41 2c |vitro.We|ydert A,|
|00003170| 20 42 61 72 74 6f 6e 20 | 50 2c 20 48 61 72 72 69 | Barton |P, Harri|
|00003180| 73 20 41 4a 2c 20 50 69 | 6e 73 65 74 20 43 2c 20 |s AJ, Pi|nset C, |
|00003190| 42 75 63 6b 69 6e 67 68 | 61 6d 20 4d 00 43 65 6c |Buckingh|am M.Cel|
|000031a0| 6c 00 34 39 00 31 32 31 | 2d 31 32 39 00 31 39 38 |l.49.121|-129.198|
|000031b0| 37 00 4a 00 00 00 4d 79 | 6f 67 65 6e 65 73 69 73 |7.J...My|ogenesis|
|000031c0| 3b 20 67 65 6e 65 20 65 | 78 70 72 65 73 73 69 6f |; gene e|xpressio|
|000031d0| 6e 3b 20 4d 48 43 2f 6d | 79 6f 73 69 6e 20 68 65 |n; MHC/m|yosin he|
|000031e0| 61 76 79 20 63 68 61 69 | 6e 20 67 65 6e 65 3b 20 |avy chai|n gene; |
|000031f0| 67 65 6e 65 20 73 77 69 | 74 63 68 69 6e 67 3b 20 |gene swi|tching; |
|00003200| 6e 65 72 76 65 20 65 66 | 66 65 63 74 73 3b 00 07 |nerve ef|fects;..|
|00003210| 33 00 01 98 1a 13 04 08 | 05 02 01 01 00 00 49 6e |3.......|......In|
|00003220| 68 69 62 69 74 69 6f 6e | 20 6f 66 20 6d 79 6f 67 |hibition| of myog|
|00003230| 65 6e 69 63 20 64 69 66 | 66 65 72 65 6e 74 69 61 |enic dif|ferentia|
|00003240| 74 69 6f 6e 20 62 79 20 | 66 69 62 72 6f 62 6c 61 |tion by |fibrobla|
|00003250| 73 74 20 67 72 6f 77 74 | 68 20 66 61 63 74 6f 72 |st growt|h factor|
|00003260| 20 6f 72 20 74 79 70 65 | 20 62 65 74 61 20 74 72 | or type| beta tr|
|00003270| 61 6e 73 66 6f 72 6d 69 | 6e 67 20 67 72 6f 77 74 |ansformi|ng growt|
|00003280| 68 20 66 61 63 74 6f 72 | 20 64 6f 65 73 20 6e 6f |h factor| does no|
|00003290| 74 20 72 65 71 75 69 72 | 65 20 70 65 72 73 69 73 |t requir|e persis|
|000032a0| 74 65 6e 74 20 63 2d 6d | 79 63 20 65 78 70 72 65 |tent c-m|yc expre|
|000032b0| 73 73 69 6f 6e 00 53 70 | 69 7a 7a 20 47 2c 20 48 |ssion.Sp|izz G, H|
|000032c0| 75 20 4a 2d 53 2c 20 4f | 6c 73 6f 6e 20 45 4e 00 |u J-S, O|lson EN.|
|000032d0| 44 65 76 65 6c 6f 70 6d | 65 6e 74 61 6c 20 42 69 |Developm|ental Bi|
|000032e0| 6f 6c 00 31 32 33 00 35 | 30 30 2d 35 30 37 00 31 |ol.123.5|00-507.1|
|000032f0| 39 38 37 00 4a 00 00 00 | 4d 79 6f 67 65 6e 65 73 |987.J...|Myogenes|
|00003300| 69 73 3b 20 42 43 33 48 | 31 20 63 65 6c 6c 20 6c |is; BC3H|1 cell l|
|00003310| 69 6e 65 3b 20 46 47 46 | 3b 20 54 47 46 3b 20 67 |ine; FGF|; TGF; g|
|00003320| 72 6f 77 74 68 20 66 61 | 63 74 6f 72 73 3b 20 6f |rowth fa|ctors; o|
|00003330| 6e 63 6f 67 65 6e 65 73 | 3b 20 63 2d 6d 79 63 3b |ncogenes|; c-myc;|
|00003340| 20 6d 6f 75 73 65 20 63 | 65 6c 6c 20 6c 69 6e 65 | mouse c|ell line|
|00003350| 3b 00 07 34 00 01 6b 16 | 05 03 06 05 02 01 01 00 |;..4..k.|........|
|00003360| 00 4f 63 63 75 70 61 74 | 69 6f 6e 20 6f 66 20 74 |.Occupat|ion of t|
|00003370| 68 65 20 65 78 74 72 61 | 63 65 6c 6c 75 6c 61 72 |he extra|cellular|
|00003380| 20 6d 61 74 72 69 78 20 | 72 65 63 65 70 74 6f 72 | matrix |receptor|
|00003390| 2c 20 69 6e 74 65 67 72 | 69 6e 2c 20 69 73 20 61 |, integr|in, is a|
|000033a0| 20 63 6f 6e 74 72 6f 6c | 20 70 6f 69 6e 74 20 66 | control| point f|
|000033b0| 6f 72 20 6d 79 6f 67 65 | 6e 69 63 20 64 69 66 66 |or myoge|nic diff|
|000033c0| 65 72 65 6e 74 69 61 74 | 69 6f 6e 00 4d 65 6e 6b |erentiat|ion.Menk|
|000033d0| 6f 20 41 53 2c 20 42 6f | 65 74 74 69 67 65 72 20 |o AS, Bo|ettiger |
|000033e0| 44 00 43 65 6c 6c 00 35 | 31 00 35 31 2d 35 37 00 |D.Cell.5|1.51-57.|
|000033f0| 31 39 38 37 00 4a 00 00 | 00 6d 79 6f 67 65 6e 65 |1987.J..|.myogene|
|00003400| 73 69 73 3b 20 43 53 41 | 54 20 61 6e 74 69 62 6f |sis; CSA|T antibo|
|00003410| 64 79 3b 20 69 6e 74 65 | 67 72 69 6e 3b 20 45 43 |dy; inte|grin; EC|
|00003420| 4d 2f 65 78 74 72 61 63 | 65 6c 6c 75 6c 61 72 20 |M/extrac|ellular |
|00003430| 6d 61 74 72 69 78 3b 20 | 6d 79 6f 62 6c 61 73 74 |matrix; |myoblast|
|00003440| 20 66 75 73 69 6f 6e 3b | 20 72 65 63 65 70 74 6f | fusion;| recepto|
|00003450| 72 73 3b 20 63 68 69 63 | 6b 65 6e 20 63 65 6c 6c |rs; chic|ken cell|
|00003460| 73 3b 00 07 35 00 01 92 | 52 0e 02 0a 05 02 01 01 |s;..5...|R.......|
|00003470| 00 00 4d 75 6c 74 69 70 | 6c 65 20 70 6f 73 69 74 |..Multip|le posit|
|00003480| 69 76 65 20 61 6e 64 20 | 6e 65 67 61 74 69 76 65 |ive and |negative|
|00003490| 20 35 27 20 72 65 67 75 | 6c 61 74 6f 72 79 20 65 | 5' regu|latory e|
|000034a0| 6c 65 6d 65 6e 74 73 20 | 63 6f 6e 74 72 6f 6c 20 |lements |control |
|000034b0| 74 68 65 20 63 65 6c 6c | 2d 74 79 70 65 2d 73 70 |the cell|-type-sp|
|000034c0| 65 63 69 66 69 63 20 65 | 78 70 72 65 73 73 69 6f |ecific e|xpressio|
|000034d0| 6e 20 6f 66 20 74 68 65 | 20 65 6d 62 72 79 6f 6e |n of the| embryon|
|000034e0| 69 63 20 73 6b 65 6c 65 | 74 61 6c 20 6d 79 6f 73 |ic skele|tal myos|
|000034f0| 69 6e 20 68 65 61 76 79 | 2d 63 68 61 69 6e 20 67 |in heavy|-chain g|
|00003500| 65 6e 65 00 42 6f 75 76 | 61 67 6e 65 74 20 50 46 |ene.Bouv|agnet PF|
|00003510| 2c 20 53 74 72 65 68 6c | 65 72 20 45 45 2c 20 57 |, Strehl|er EE, W|
|00003520| 68 69 74 65 20 47 45 2c | 20 53 74 72 65 68 6c 65 |hite GE,| Strehle|
|00003530| 72 2d 50 61 67 65 20 4d | 2d 41 2c 20 4e 61 64 61 |r-Page M|-A, Nada|
|00003540| 6c 2d 47 69 6e 61 72 64 | 20 42 2c 20 4d 61 68 64 |l-Ginard| B, Mahd|
|00003550| 61 76 69 20 56 00 4d 6f | 6c 20 43 65 6c 6c 20 42 |avi V.Mo|l Cell B|
|00003560| 69 6f 6c 00 37 00 34 33 | 37 37 2d 34 33 38 39 00 |iol.7.43|77-4389.|
|00003570| 31 39 38 37 00 4a 00 00 | 00 6d 79 6f 67 65 6e 65 |1987.J..|.myogene|
|00003580| 73 69 73 3b 20 4d 48 43 | 20 67 65 6e 65 3b 20 6d |sis; MHC| gene; m|
|00003590| 79 6f 73 69 6e 20 68 65 | 61 76 79 20 63 68 61 69 |yosin he|avy chai|
|000035a0| 6e 20 67 65 6e 65 3b 20 | 67 65 6e 65 20 65 78 70 |n gene; |gene exp|
|000035b0| 72 65 73 73 69 6f 6e 3b | 20 74 72 61 6e 73 2d 61 |ression;| trans-a|
|000035c0| 63 74 69 6e 67 20 66 61 | 63 74 6f 72 73 3b 20 6d |cting fa|ctors; m|
|000035d0| 6f 75 73 65 20 43 32 43 | 31 32 20 63 65 6c 6c 73 |ouse C2C|12 cells|
|000035e0| 3b 20 70 72 6f 6d 6f 74 | 65 72 20 65 6e 68 61 6e |; promot|er enhan|
|000035f0| 63 65 72 3b 00 07 36 00 | 01 4a 23 0e 02 08 05 02 |cer;..6.|.J#.....|
|00003600| 01 01 00 00 41 20 6e 6f | 76 65 6c 20 72 61 70 69 |....A no|vel rapi|
|00003610| 64 20 61 73 73 61 79 20 | 66 6f 72 20 63 68 6c 6f |d assay |for chlo|
|00003620| 72 61 6d 70 68 65 6e 69 | 63 6f 6c 20 61 63 65 74 |rampheni|col acet|
|00003630| 79 6c 74 72 61 6e 73 66 | 65 72 61 73 65 20 67 65 |yltransf|erase ge|
|00003640| 6e 65 20 65 78 70 72 65 | 73 73 69 6f 6e 00 4e 65 |ne expre|ssion.Ne|
|00003650| 75 6d 61 6e 6e 20 4a 52 | 2c 20 4d 6f 72 65 6e 63 |umann JR|, Morenc|
|00003660| 79 20 43 41 2c 20 52 75 | 73 73 69 61 6e 20 4b 4f |y CA, Ru|ssian KO|
|00003670| 00 42 69 6f 54 65 63 68 | 6e 69 71 75 65 73 00 35 |.BioTech|niques.5|
|00003680| 00 34 34 34 2d 34 34 37 | 00 31 39 38 37 00 4a 00 |.444-447|.1987.J.|
|00003690| 00 00 4d 65 74 68 6f 64 | 73 3b 20 43 41 54 20 61 |..Method|s; CAT a|
|000036a0| 73 73 61 79 3b 20 63 68 | 6c 6f 72 61 6d 70 68 65 |ssay; ch|loramphe|
|000036b0| 6e 69 63 6f 6c 20 61 63 | 65 74 79 6c 74 72 61 6e |nicol ac|etyltran|
|000036c0| 73 66 65 72 61 73 65 3b | 20 70 72 6f 6d 6f 74 65 |sferase;| promote|
|000036d0| 72 2f 65 6e 68 61 6e 63 | 65 72 20 61 63 74 69 76 |r/enhanc|er activ|
|000036e0| 69 74 79 3b 00 07 37 00 | 01 25 08 0a 01 08 05 02 |ity;..7.|.%......|
|000036f0| 38 2a 00 00 41 20 62 65 | 67 69 6e 6e 65 72 27 73 |8*..A be|ginner's|
|00003700| 20 67 75 69 64 65 20 74 | 6f 20 6c 61 6d 62 64 61 | guide t|o lambda|
|00003710| 20 62 69 6f 6c 6f 67 79 | 00 41 72 62 65 72 20 57 | biology|.Arber W|
|00003720| 00 4c 61 6d 62 64 61 20 | 49 49 00 00 33 38 31 2d |.Lambda |II..381-|
|00003730| 33 39 34 00 31 39 38 33 | 00 42 00 52 2e 57 2e 20 |394.1983|.B.R.W. |
|00003740| 48 65 6e 64 72 69 78 2c | 20 4a 2e 57 2e 20 52 6f |Hendrix,| J.W. Ro|
|00003750| 62 65 72 74 73 2c 20 46 | 2e 57 2e 20 53 74 61 68 |berts, F|.W. Stah|
|00003760| 6c 2c 20 26 20 52 2e 41 | 2e 20 57 65 69 73 62 65 |l, & R.A|. Weisbe|
|00003770| 72 67 00 43 6f 6c 64 20 | 53 70 72 69 6e 67 20 48 |rg.Cold |Spring H|
|00003780| 61 72 62 6f 72 20 4c 61 | 62 6f 72 61 74 6f 72 79 |arbor La|boratory|
|00003790| 2c 20 4c 49 2c 20 4e 59 | 20 55 53 41 00 42 61 63 |, LI, NY| USA.Bac|
|000037a0| 6b 67 72 6f 75 6e 64 3b | 20 6c 61 6d 62 64 61 20 |kground;| lambda |
|000037b0| 70 68 61 67 65 3b 20 62 | 61 63 74 65 72 69 6f 70 |phage; b|acteriop|
|000037c0| 68 61 67 65 3b 20 63 49 | 3b 20 63 72 6f 20 70 72 |hage; cI|; cro pr|
|000037d0| 6f 74 65 69 6e 3b 20 6c | 79 73 69 73 2f 6c 79 73 |otein; l|ysis/lys|
|000037e0| 6f 67 65 6e 79 3b 20 45 | 2e 20 63 6f 6c 69 00 07 |ogeny; E|. coli..|
|000037f0| 38 00 01 23 0a 0a 01 08 | 05 02 38 2a 00 00 50 68 |8..#....|..8*..Ph|
|00003800| 61 67 65 20 6c 61 6d 62 | 64 61 20 61 6e 64 20 6d |age lamb|da and m|
|00003810| 6f 6c 65 63 75 6c 61 72 | 20 63 6c 6f 6e 69 6e 67 |olecular| cloning|
|00003820| 00 4d 75 72 72 61 79 20 | 4e 45 00 4c 61 6d 62 64 |.Murray |NE.Lambd|
|00003830| 61 20 49 49 00 00 33 39 | 35 2d 34 33 32 00 31 39 |a II..39|5-432.19|
|00003840| 38 33 00 42 00 52 2e 57 | 2e 20 48 65 6e 64 72 69 |83.B.R.W|. Hendri|
|00003850| 78 2c 20 4a 2e 57 2e 20 | 52 6f 62 65 72 74 73 2c |x, J.W. |Roberts,|
|00003860| 20 46 2e 57 2e 20 53 74 | 61 68 6c 2c 20 26 20 52 | F.W. St|ahl, & R|
|00003870| 2e 41 2e 20 57 65 69 73 | 62 65 72 67 00 43 6f 6c |.A. Weis|berg.Col|
|00003880| 64 20 53 70 72 69 6e 67 | 20 48 61 72 62 6f 72 20 |d Spring| Harbor |
|00003890| 4c 61 62 6f 72 61 74 6f | 72 79 2c 20 4c 49 2c 20 |Laborato|ry, LI, |
|000038a0| 4e 59 20 55 53 41 00 42 | 61 63 6b 67 72 6f 75 6e |NY USA.B|ackgroun|
|000038b0| 64 3b 20 6c 61 6d 62 64 | 61 20 70 68 61 67 65 3b |d; lambd|a phage;|
|000038c0| 20 62 61 63 74 65 72 69 | 6f 70 68 61 67 65 3b 20 | bacteri|ophage; |
|000038d0| 45 2e 20 63 6f 6c 69 3b | 20 6c 61 6d 62 64 61 20 |E. coli;| lambda |
|000038e0| 76 65 63 74 6f 72 73 3b | 20 73 70 69 2b 20 73 65 |vectors;| spi+ se|
|000038f0| 6c 65 63 74 69 6f 6e 3b | 20 63 68 69 20 73 65 71 |lection;| chi seq|
|00003900| 75 65 6e 63 65 3b 20 72 | 65 64 2d 20 67 61 6d 2d |uence; r|ed- gam-|
|00003910| 3b 20 63 6c 6f 6e 69 6e | 67 3b 20 72 65 63 6f 6d |; clonin|g; recom|
|00003920| 62 69 6e 61 6e 74 73 00 | 07 39 00 01 29 30 0a 01 |binants.|.9..)0..|
|00003930| 08 05 02 38 2a 00 00 45 | 78 70 65 72 69 6d 65 6e |...8*..E|xperimen|
|00003940| 74 61 6c 20 6d 65 74 68 | 6f 64 73 20 66 6f 72 20 |tal meth|ods for |
|00003950| 75 73 65 20 77 69 74 68 | 20 6c 61 6d 62 64 61 00 |use with| lambda.|
|00003960| 41 72 62 65 72 20 57 2c | 20 45 6e 71 75 69 73 74 |Arber W,| Enquist|
|00003970| 20 4c 2c 20 48 6f 68 6e | 20 42 2c 20 4d 75 72 72 | L, Hohn| B, Murr|
|00003980| 61 79 20 4e 45 2c 20 4d | 75 72 72 61 79 20 4b 00 |ay NE, M|urray K.|
|00003990| 4c 61 6d 62 64 61 20 49 | 49 00 00 34 33 33 2d 34 |Lambda I|I..433-4|
|000039a0| 36 36 00 31 39 38 33 00 | 42 00 52 2e 57 2e 20 48 |66.1983.|B.R.W. H|
|000039b0| 65 6e 64 72 69 78 2c 20 | 4a 2e 57 2e 20 52 6f 62 |endrix, |J.W. Rob|
|000039c0| 65 72 74 73 2c 20 46 2e | 57 2e 20 53 74 61 68 6c |erts, F.|W. Stahl|
|000039d0| 2c 20 26 20 52 2e 41 2e | 20 57 65 69 73 62 65 72 |, & R.A.| Weisber|
|000039e0| 67 00 43 6f 6c 64 20 53 | 70 72 69 6e 67 20 48 61 |g.Cold S|pring Ha|
|000039f0| 72 62 6f 72 20 4c 61 62 | 6f 72 61 74 6f 72 79 2c |rbor Lab|oratory,|
|00003a00| 20 4c 49 2c 20 4e 59 20 | 55 53 41 00 42 61 63 6b | LI, NY |USA.Back|
|00003a10| 67 72 6f 75 6e 64 3b 20 | 52 65 76 69 65 77 3b 20 |ground; |Review; |
|00003a20| 6c 61 6d 62 64 61 20 70 | 68 61 67 65 3b 20 62 61 |lambda p|hage; ba|
|00003a30| 63 74 65 72 69 6f 70 68 | 61 67 65 3b 20 6c 61 6d |cterioph|age; lam|
|00003a40| 64 61 20 76 65 63 74 6f | 72 73 3b 20 63 6c 6f 6e |da vecto|rs; clon|
|00003a50| 69 6e 67 3b 20 45 2e 20 | 63 6f 6c 69 3b 20 73 70 |ing; E. |coli; sp|
|00003a60| 69 2d 20 70 68 65 6e 6f | 74 79 70 65 3b 20 6d 75 |i- pheno|type; mu|
|00003a70| 74 61 6e 74 73 3b 20 69 | 6e 64 75 63 74 69 6f 6e |tants; i|nduction|
|00003a80| 3b 20 70 75 72 69 66 69 | 63 61 74 69 6f 6e 00 07 |; purifi|cation..|
|00003a90| 3a 00 01 5c 36 0c 04 06 | 05 02 01 01 00 00 27 45 |:..\6...|......'E|
|00003aa0| 61 72 6c 79 27 20 6d 61 | 6d 6d 61 6c 69 61 6e 20 |arly' ma|mmalian |
|00003ab0| 6d 79 6f 62 6c 61 73 74 | 73 20 61 72 65 20 72 65 |myoblast|s are re|
|00003ac0| 73 69 73 74 61 6e 74 20 | 74 6f 20 70 68 6f 72 62 |sistant |to phorb|
|00003ad0| 6f 6c 20 65 73 74 65 72 | 2d 69 6e 64 75 63 65 64 |ol ester|-induced|
|00003ae0| 20 62 6c 6f 63 6b 20 6f | 66 20 64 69 66 66 65 72 | block o|f differ|
|00003af0| 65 6e 74 69 61 74 69 6f | 6e 00 43 6f 73 73 75 20 |entiatio|n.Cossu |
|00003b00| 47 2c 20 52 61 6e 61 6c | 64 69 20 47 2c 20 53 65 |G, Ranal|di G, Se|
|00003b10| 6e 6e 69 20 4d 49 2c 20 | 4d 6f 6c 69 6e 61 72 6f |nni MI, |Molinaro|
|00003b20| 20 4d 2c 20 56 69 76 61 | 72 65 6c 6c 69 20 45 00 | M, Viva|relli E.|
|00003b30| 44 65 76 65 6c 6f 70 6d | 65 6e 74 00 31 30 32 00 |Developm|ent.102.|
|00003b40| 36 35 2d 36 39 00 31 39 | 38 38 00 4a 00 00 00 4d |65-69.19|88.J...M|
|00003b50| 79 6f 67 65 6e 65 73 69 | 73 3b 20 6d 79 6f 62 6c |yogenesi|s; myobl|
|00003b60| 61 73 74 20 74 79 70 65 | 73 3b 20 70 68 6f 72 62 |ast type|s; phorb|
|00003b70| 6f 6c 20 65 73 74 65 72 | 73 2f 54 50 41 3b 73 61 |ol ester|s/TPA;sa|
|00003b80| 74 65 6c 6c 69 74 65 20 | 63 65 6c 6c 73 3b 20 74 |tellite |cells; t|
|00003b90| 75 6d 6f 72 20 70 72 6f | 6d 6f 74 65 72 73 3b 6d |umor pro|moters;m|
|00003ba0| 6f 75 73 65 20 65 6d 62 | 72 79 6f 73 3b 64 69 66 |ouse emb|ryos;dif|
|00003bb0| 66 65 72 65 6e 74 69 61 | 74 69 6f 6e 20 69 6e 68 |ferentia|tion inh|
|00003bc0| 69 62 69 74 6f 72 00 07 | 3b 00 01 60 43 07 04 08 |ibitor..|;..`C...|
|00003bd0| 05 02 01 01 00 00 52 65 | 71 75 69 72 65 6d 65 6e |......Re|quiremen|
|00003be0| 74 20 6f 66 20 73 74 65 | 72 65 6f 73 70 65 63 69 |t of ste|reospeci|
|00003bf0| 66 69 63 20 61 6c 69 67 | 6e 6d 65 6e 74 73 20 66 |fic alig|nments f|
|00003c00| 6f 72 20 69 6e 69 74 69 | 61 74 69 6f 6e 20 66 72 |or initi|ation fr|
|00003c10| 6f 6d 20 74 68 65 20 73 | 69 6d 69 61 6e 20 76 69 |om the s|imian vi|
|00003c20| 72 75 73 20 34 30 20 65 | 61 72 6c 79 20 70 72 6f |rus 40 e|arly pro|
|00003c30| 6d 6f 74 65 72 00 54 61 | 6b 61 68 61 73 68 69 20 |moter.Ta|kahashi |
|00003c40| 4b 2c 20 56 69 67 6e 65 | 72 6f 6e 20 4d 2c 20 4d |K, Vigne|ron M, M|
|00003c50| 61 74 74 68 65 73 20 48 | 2c 20 57 69 6c 64 65 6d |atthes H|, Wildem|
|00003c60| 61 6e 20 41 2c 20 5a 65 | 6e 6b 65 20 4d 2c 20 43 |an A, Ze|nke M, C|
|00003c70| 68 61 6d 62 6f 6e 20 50 | 00 4e 61 74 75 72 65 00 |hambon P|.Nature.|
|00003c80| 33 31 39 00 31 32 31 2d | 31 32 36 00 31 39 38 36 |319.121-|126.1986|
|00003c90| 00 4a 00 00 00 53 56 34 | 30 20 65 6e 68 61 6e 63 |.J...SV4|0 enhanc|
|00003ca0| 65 72 2f 70 72 6f 6d 6f | 74 65 72 3b 74 72 61 6e |er/promo|ter;tran|
|00003cb0| 73 63 72 69 70 74 69 6f | 6e 3b 67 65 6e 65 20 65 |scriptio|n;gene e|
|00003cc0| 78 70 72 65 73 73 69 6f | 6e 3b 61 6c 69 67 6e 6d |xpressio|n;alignm|
|00003cd0| 65 6e 74 3b 20 63 69 73 | 2d 72 65 67 75 6c 61 74 |ent; cis|-regulat|
|00003ce0| 6f 72 79 20 72 65 67 69 | 6f 6e 73 3b 73 74 65 72 |ory regi|ons;ster|
|00003cf0| 65 6f 73 70 65 63 69 66 | 69 63 69 74 79 3b 70 6f |eospecif|icity;po|
|00003d00| 6c 20 49 49 3b 44 4e 41 | 20 68 65 6c 69 78 00 07 |l II;DNA| helix..|
|00003d10| 3c 00 01 90 52 0e 02 0a | 05 02 01 01 00 00 54 68 |<...R...|......Th|
|00003d20| 65 20 72 61 74 20 65 6c | 61 73 74 61 73 65 20 49 |e rat el|astase I|
|00003d30| 20 72 65 67 75 6c 61 74 | 6f 72 79 20 65 6c 65 6d | regulat|ory elem|
|00003d40| 65 6e 74 20 69 73 20 61 | 6e 20 65 6e 68 61 6e 63 |ent is a|n enhanc|
|00003d50| 65 72 20 74 68 61 74 20 | 64 69 72 65 63 74 73 20 |er that |directs |
|00003d60| 63 6f 72 72 65 63 74 20 | 63 65 6c 6c 20 73 70 65 |correct |cell spe|
|00003d70| 63 69 66 69 63 69 74 79 | 20 61 6e 64 20 64 65 76 |cificity| and dev|
|00003d80| 65 6c 6f 70 6d 65 6e 74 | 61 6c 20 6f 6e 73 65 74 |elopment|al onset|
|00003d90| 20 6f 66 20 65 78 70 72 | 65 73 73 69 6f 6e 20 69 | of expr|ession i|
|00003da0| 6e 20 74 72 61 6e 73 67 | 65 6e 69 63 20 00 48 61 |n transg|enic .Ha|
|00003db0| 6d 6d 65 72 20 52 45 2c | 20 53 77 69 66 74 20 47 |mmer RE,| Swift G|
|00003dc0| 48 2c 20 4f 72 6e 69 74 | 7a 20 44 4d 2c 20 51 75 |H, Ornit|z DM, Qu|
|00003dd0| 61 69 66 65 20 43 4a 2c | 20 50 61 6c 6d 69 74 65 |aife CJ,| Palmite|
|00003de0| 72 20 52 44 2c 20 42 72 | 69 6e 73 74 65 72 20 52 |r RD, Br|inster R|
|00003df0| 4c 2c 20 4d 61 63 44 6f | 6e 61 6c 64 20 52 4a 00 |L, MacDo|nald RJ.|
|00003e00| 4d 6f 6c 20 43 65 6c 6c | 20 42 69 6f 6c 00 37 00 |Mol Cell| Biol.7.|
|00003e10| 32 39 35 36 2d 32 39 36 | 37 00 31 39 38 37 00 4a |2956-296|7.1987.J|
|00003e20| 00 00 00 41 64 76 2e 43 | 26 4d 42 3b 72 61 74 3b |...Adv.C|&MB;rat;|
|00003e30| 65 6c 61 73 74 61 73 65 | 20 49 20 67 65 6e 65 3b |elastase| I gene;|
|00003e40| 74 72 61 6e 73 67 65 6e | 69 63 20 6d 69 63 65 3b |transgen|ic mice;|
|00003e50| 65 6e 68 61 6e 63 65 72 | 3b 67 65 6e 65 20 65 78 |enhancer|;gene ex|
|00003e60| 70 72 65 73 73 69 6f 6e | 3b 63 69 73 2d 61 63 74 |pression|;cis-act|
|00003e70| 69 6e 67 20 65 6c 65 6d | 65 6e 74 73 3b 64 65 76 |ing elem|ents;dev|
|00003e80| 65 6c 6f 70 6d 65 6e 74 | 61 6c 20 67 65 6e 65 20 |elopment|al gene |
|00003e90| 65 78 70 72 65 73 73 69 | 6f 6e 3b 67 72 6f 77 74 |expressi|on;growt|
|00003ea0| 68 20 68 6f 72 6d 6f 6e | 65 00 07 3d 00 01 5d 35 |h hormon|e..=..]5|
|00003eb0| 05 03 08 05 02 01 01 00 | 00 50 6f 73 69 74 69 6f |........|.Positio|
|00003ec0| 6e 2d 69 6e 64 65 70 65 | 6e 64 65 6e 74 2c 20 68 |n-indepe|ndent, h|
|00003ed0| 69 67 68 2d 6c 65 76 65 | 6c 20 65 78 70 72 65 73 |igh-leve|l expres|
|00003ee0| 73 69 6f 6e 20 6f 66 20 | 74 68 65 20 68 75 6d 61 |sion of |the huma|
|00003ef0| 6e 20 62 65 74 61 2d 67 | 6c 6f 62 69 6e 20 67 65 |n beta-g|lobin ge|
|00003f00| 6e 65 20 69 6e 20 74 72 | 61 6e 73 67 65 6e 69 63 |ne in tr|ansgenic|
|00003f10| 20 6d 69 63 65 00 47 72 | 6f 73 76 65 6c 64 20 46 | mice.Gr|osveld F|
|00003f20| 2c 20 41 73 73 65 6e 64 | 65 6c 66 74 20 47 42 20 |, Assend|elft GB |
|00003f30| 76 61 6e 2c 20 47 72 65 | 61 76 65 73 20 44 52 2c |van, Gre|aves DR,|
|00003f40| 20 4b 6f 6c 6c 69 61 73 | 20 47 00 43 65 6c 6c 00 | Kollias| G.Cell.|
|00003f50| 35 31 00 39 37 35 2d 39 | 38 35 00 31 39 38 37 00 |51.975-9|85.1987.|
|00003f60| 4a 00 00 00 41 64 76 2e | 43 26 4d 42 3b 68 75 6d |J...Adv.|C&MB;hum|
|00003f70| 61 6e 3b 74 72 61 6e 73 | 67 65 6e 69 63 20 6d 69 |an;trans|genic mi|
|00003f80| 63 65 3b 62 65 74 61 2d | 67 6c 6f 62 69 6e 20 67 |ce;beta-|globin g|
|00003f90| 65 6e 65 3b 70 6f 73 69 | 74 69 6f 6e 20 65 66 66 |ene;posi|tion eff|
|00003fa0| 65 63 74 73 3b 20 74 69 | 73 73 75 65 2d 73 70 65 |ects; ti|ssue-spe|
|00003fb0| 63 69 66 69 63 20 67 65 | 6e 65 20 65 78 70 72 65 |cific ge|ne expre|
|00003fc0| 73 73 69 6f 6e 3b 69 6e | 74 65 67 72 61 74 69 6f |ssion;in|tegratio|
|00003fd0| 6e 3b 63 68 72 6f 6d 61 | 74 69 6e 20 73 74 72 75 |n;chroma|tin stru|
|00003fe0| 63 74 75 72 65 3b 72 65 | 67 75 6c 61 74 69 6f 6e |cture;re|gulation|
|00003ff0| 00 07 3e 00 01 70 3d 05 | 03 08 05 02 01 01 00 00 |..>..p=.|........|
|00004000| 43 6f 65 78 70 72 65 73 | 73 69 6f 6e 20 6f 66 20 |Coexpres|sion of |
|00004010| 4d 4d 54 56 2f 76 2d 48 | 61 2d 72 61 73 20 61 6e |MMTV/v-H|a-ras an|
|00004020| 64 20 4d 4d 54 56 2f 63 | 2d 6d 79 63 20 67 65 6e |d MMTV/c|-myc gen|
|00004030| 65 73 20 69 6e 20 74 72 | 61 6e 73 67 65 6e 69 63 |es in tr|ansgenic|
|00004040| 20 6d 69 63 65 3a 20 20 | 53 79 6e 65 72 67 69 73 | mice:  |Synergis|
|00004050| 74 69 63 20 61 63 74 69 | 6f 6e 20 6f 66 20 6f 6e |tic acti|on of on|
|00004060| 63 6f 67 65 6e 65 73 20 | 69 6e 20 76 69 76 6f 00 |cogenes |in vivo.|
|00004070| 53 69 6e 6e 20 45 2c 20 | 4d 75 6c 6c 65 72 20 57 |Sinn E, |Muller W|
|00004080| 2c 20 50 61 74 74 65 6e | 67 61 6c 65 20 50 2c 20 |, Patten|gale P, |
|00004090| 54 65 70 6c 65 72 20 49 | 2c 20 57 61 6c 6c 61 63 |Tepler I|, Wallac|
|000040a0| 65 20 52 2c 20 4c 65 64 | 65 72 20 50 00 43 65 6c |e R, Led|er P.Cel|
|000040b0| 6c 00 34 39 00 34 36 35 | 2d 34 37 35 00 31 39 38 |l.49.465|-475.198|
|000040c0| 37 00 4a 00 00 00 41 64 | 76 2e 43 26 4d 42 3b 74 |7.J...Ad|v.C&MB;t|
|000040d0| 72 61 6e 73 67 65 6e 69 | 63 20 6d 69 63 65 3b 6f |ransgeni|c mice;o|
|000040e0| 6e 63 6f 67 65 6e 65 73 | 3b 63 2d 6d 79 63 3b 76 |ncogenes|;c-myc;v|
|000040f0| 2d 48 61 2d 72 61 73 3b | 73 79 6e 65 72 67 69 73 |-Ha-ras;|synergis|
|00004100| 6d 3b 20 4d 4d 54 56 20 | 70 72 6f 6d 6f 74 65 72 |m; MMTV |promoter|
|00004110| 2f 65 6e 68 61 6e 63 65 | 72 3b 74 75 6d 6f 72 73 |/enhance|r;tumors|
|00004120| 3b 6d 61 6c 69 67 6e 61 | 6e 63 79 3b 63 61 6e 63 |;maligna|ncy;canc|
|00004130| 65 72 20 70 72 6f 67 72 | 65 73 73 69 6f 6e 3b 00 |er progr|ession;.|
|00004140| 07 3f 00 01 5d 3a 08 04 | 08 05 02 01 01 00 00 50 |.?..]:..|.......P|
|00004150| 61 6e 63 72 65 61 74 69 | 63 20 6e 65 6f 70 6c 61 |ancreati|c neopla|
|00004160| 73 69 61 20 69 6e 64 75 | 63 65 64 20 62 79 20 53 |sia indu|ced by S|
|00004170| 56 34 30 20 54 2d 61 6e | 74 69 67 65 6e 20 65 78 |V40 T-an|tigen ex|
|00004180| 70 72 65 73 73 69 6f 6e | 20 69 6e 20 61 63 69 6e |pression| in acin|
|00004190| 61 72 20 63 65 6c 6c 73 | 20 6f 66 20 74 72 61 6e |ar cells| of tran|
|000041a0| 73 67 65 6e 69 63 20 6d | 69 63 65 00 4f 72 6e 69 |sgenic m|ice.Orni|
|000041b0| 74 7a 20 44 4d 2c 20 48 | 61 6d 6d 65 72 20 52 45 |tz DM, H|ammer RE|
|000041c0| 2c 20 4d 65 73 73 69 6e | 67 20 41 2c 20 50 61 6c |, Messin|g A, Pal|
|000041d0| 6d 69 74 65 72 20 52 44 | 2c 20 42 72 69 6e 73 74 |miter RD|, Brinst|
|000041e0| 65 72 20 52 4c 00 53 63 | 69 65 6e 63 65 00 32 33 |er RL.Sc|ience.23|
|000041f0| 38 00 31 38 38 2d 31 39 | 33 00 31 39 38 37 00 4a |8.188-19|3.1987.J|
|00004200| 00 00 00 41 64 76 2e 43 | 26 4d 42 3b 74 72 61 6e |...Adv.C|&MB;tran|
|00004210| 73 67 65 6e 69 63 20 6d | 69 63 65 3b 63 61 6e 63 |sgenic m|ice;canc|
|00004220| 65 72 3b 6e 65 6f 70 6c | 61 73 69 61 3b 53 56 34 |er;neopl|asia;SV4|
|00004230| 30 20 54 2d 61 6e 74 69 | 67 65 6e 3b 61 63 69 6e |0 T-anti|gen;acin|
|00004240| 61 72 20 63 65 6c 6c 73 | 3b 6d 6f 75 73 65 3b 70 |ar cells|;mouse;p|
|00004250| 61 6e 63 72 65 61 73 3b | 63 65 6c 6c 20 64 69 66 |ancreas;|cell dif|
|00004260| 66 65 72 65 6e 74 69 61 | 74 69 6f 6e 00 07 40 00 |ferentia|tion..@.|
|00004270| 01 86 1b 0c 04 0a 05 02 | 01 01 00 00 42 69 6f 73 |........|....Bios|
|00004280| 79 6e 74 68 65 73 69 73 | 2c 20 6d 65 6d 62 72 61 |ynthesis|, membra|
|00004290| 6e 65 20 61 73 73 6f 63 | 69 61 74 69 6f 6e 2c 20 |ne assoc|iation, |
|000042a0| 61 6e 64 20 72 65 6c 65 | 61 73 65 20 6f 66 20 4e |and rele|ase of N|
|000042b0| 2d 43 41 4d 2d 31 32 30 | 2c 20 61 20 70 68 6f 73 |-CAM-120|, a phos|
|000042c0| 70 68 61 74 69 64 79 6c | 69 6e 6f 73 69 74 6f 6c |phatidyl|inositol|
|000042d0| 2d 6c 69 6e 6b 65 64 20 | 66 6f 72 6d 20 6f 66 20 |-linked |form of |
|000042e0| 74 68 65 20 4e 65 75 72 | 61 6c 20 43 65 6c 6c 20 |the Neur|al Cell |
|000042f0| 41 64 68 65 73 69 6f 6e | 20 4d 6f 6c 65 63 75 6c |Adhesion| Molecul|
|00004300| 65 00 48 65 20 48 2d 54 | 2c 20 46 69 6e 6e 65 20 |e.He H-T|, Finne |
|00004310| 4a 2c 20 47 6f 72 69 64 | 69 73 20 43 00 4a 20 43 |J, Gorid|is C.J C|
|00004320| 65 6c 6c 20 42 69 6f 6c | 00 31 30 35 00 32 34 38 |ell Biol|.105.248|
|00004330| 39 2d 32 35 30 30 00 31 | 39 38 37 00 4a 00 00 00 |9-2500.1|987.J...|
|00004340| 41 64 76 2e 43 26 4d 42 | 3b 4e 43 41 4d 3b 4e 2d |Adv.C&MB|;NCAM;N-|
|00004350| 43 41 4d 3b 72 61 74 3b | 70 68 6f 73 70 68 61 74 |CAM;rat;|phosphat|
|00004360| 69 64 79 6c 69 6e 6f 73 | 69 74 6f 6c 3b 6d 65 6d |idylinos|itol;mem|
|00004370| 62 72 61 6e 65 20 70 72 | 6f 74 65 69 6e 3b 20 70 |brane pr|otein; p|
|00004380| 72 6f 74 65 69 6e 20 62 | 69 6f 73 79 6e 74 68 65 |rotein b|iosynthe|
|00004390| 73 69 73 3b 65 6e 64 6f | 48 3b 70 6f 6c 79 73 69 |sis;endo|H;polysi|
|000043a0| 61 6c 79 6c 61 74 69 6f | 6e 3b 70 6f 6c 79 73 69 |alylatio|n;polysi|
|000043b0| 61 6c 69 63 20 61 63 69 | 64 3b 70 68 6f 73 70 68 |alic aci|d;phosph|
|000043c0| 6f 6c 69 70 61 73 65 20 | 43 00 07 41 00 01 82 23 |olipase |C..A...#|
|000043d0| 0c 04 08 05 02 01 01 00 | 00 53 65 71 75 65 6e 74 |........|.Sequent|
|000043e0| 69 61 6c 20 65 78 70 72 | 65 73 73 69 6f 6e 20 61 |ial expr|ession a|
|000043f0| 6e 64 20 64 69 66 66 65 | 72 65 6e 74 69 61 6c 20 |nd diffe|rential |
|00004400| 66 75 6e 63 74 69 6f 6e | 20 6f 66 20 6d 75 6c 74 |function| of mult|
|00004410| 69 70 6c 65 20 61 64 68 | 65 73 69 6f 6e 20 6d 6f |iple adh|esion mo|
|00004420| 6c 65 63 75 6c 65 73 20 | 64 75 72 69 6e 67 20 74 |lecules |during t|
|00004430| 68 65 20 66 6f 72 6d 61 | 74 69 6f 6e 20 6f 66 20 |he forma|tion of |
|00004440| 63 65 72 65 62 65 6c 6c | 61 72 20 63 6f 72 74 69 |cerebell|ar corti|
|00004450| 63 61 6c 20 6c 61 79 65 | 72 73 00 43 68 75 6f 6e |cal laye|rs.Chuon|
|00004460| 67 20 43 2d 4d 2c 20 43 | 72 6f 73 73 69 6e 20 4b |g C-M, C|rossin K|
|00004470| 4c 2c 20 45 64 65 6c 6d | 61 6e 20 47 4d 00 4a 20 |L, Edelm|an GM.J |
|00004480| 43 65 6c 6c 20 42 69 6f | 6c 00 31 30 34 00 33 33 |Cell Bio|l.104.33|
|00004490| 31 2d 33 34 32 00 31 39 | 38 37 00 4a 00 00 00 41 |1-342.19|87.J...A|
|000044a0| 64 76 2e 43 26 4d 42 3b | 4e 43 41 4d 3b 4e 2d 43 |dv.C&MB;|NCAM;N-C|
|000044b0| 41 4d 3b 63 65 72 65 62 | 65 6c 6c 61 72 20 64 65 |AM;cereb|ellar de|
|000044c0| 76 65 6c 6f 70 6d 65 6e | 74 3b 63 79 74 6f 74 61 |velopmen|t;cytota|
|000044d0| 63 74 69 6e 3b 4e 67 2d | 43 41 4d 3b 20 4e 67 43 |ctin;Ng-|CAM; NgC|
|000044e0| 41 4d 3b 63 68 69 63 6b | 65 6e 3b 6e 65 75 72 6f |AM;chick|en;neuro|
|000044f0| 6e 20 64 65 76 65 6c 6f | 70 6d 65 6e 74 3b 63 65 |n develo|pment;ce|
|00004500| 6c 6c 20 64 69 66 66 65 | 72 65 6e 74 69 61 74 69 |ll diffe|rentiati|
|00004510| 6f 6e 3b 63 65 6c 6c 20 | 61 64 68 65 73 69 6f 6e |on;cell |adhesion|
|00004520| 20 6d 6f 6c 65 63 75 6c | 65 00 07 42 00 01 3a 19 | molecul|e..B..:.|
|00004530| 05 03 08 05 02 01 01 00 | 00 50 61 74 74 65 72 6e |........|.Pattern|
|00004540| 20 66 6f 72 6d 61 74 69 | 6f 6e 20 64 75 72 69 6e | formati|on durin|
|00004550| 67 20 76 75 6c 76 61 6c | 20 64 65 76 65 6c 6f 70 |g vulval| develop|
|00004560| 6d 65 6e 74 20 69 6e 20 | 43 2e 20 65 6c 65 67 61 |ment in |C. elega|
|00004570| 6e 73 00 53 74 65 72 6e | 62 65 72 67 20 50 57 2c |ns.Stern|berg PW,|
|00004580| 20 48 6f 72 76 69 74 7a | 20 48 52 00 43 65 6c 6c | Horvitz| HR.Cell|
|00004590| 00 34 34 00 37 36 31 2d | 37 37 32 00 31 39 38 36 |.44.761-|772.1986|
|000045a0| 00 4a 00 00 00 41 64 76 | 2e 43 26 4d 42 3b 52 65 |.J...Adv|.C&MB;Re|
|000045b0| 76 69 65 77 3b 43 2e 65 | 6c 65 67 61 6e 73 3b 76 |view;C.e|legans;v|
|000045c0| 75 6c 76 61 6c 20 64 65 | 76 65 6c 6f 70 6d 65 6e |ulval de|velopmen|
|000045d0| 74 3b 63 65 6c 6c 20 64 | 69 66 66 65 72 65 6e 74 |t;cell d|ifferent|
|000045e0| 69 61 74 69 6f 6e 3b 20 | 70 61 74 74 65 72 6e 20 |iation; |pattern |
|000045f0| 66 6f 72 6d 61 74 69 6f | 6e 3b 63 65 6c 6c 20 66 |formatio|n;cell f|
|00004600| 61 74 65 3b 63 65 6c 6c | 20 63 6f 6d 6d 69 74 6d |ate;cell| commitm|
|00004610| 65 6e 74 2f 64 65 74 65 | 72 6d 69 6e 61 74 69 6f |ent/dete|rminatio|
|00004620| 6e 3b 61 6e 63 68 6f 72 | 20 63 65 6c 6c 00 07 43 |n;anchor| cell..C|
|00004630| 00 01 5e 26 07 04 04 05 | 02 01 01 00 00 41 20 67 |..^&....|.....A g|
|00004640| 65 6e 65 74 69 63 20 70 | 61 74 68 77 61 79 20 66 |enetic p|athway f|
|00004650| 6f 72 20 74 68 65 20 73 | 70 65 63 69 66 69 63 61 |or the s|pecifica|
|00004660| 74 69 6f 6e 20 6f 66 20 | 74 68 65 20 76 75 6c 76 |tion of |the vulv|
|00004670| 61 6c 20 63 65 6c 6c 20 | 6c 69 6e 65 61 67 65 73 |al cell |lineages|
|00004680| 20 6f 66 20 43 61 65 6e | 6f 72 68 61 62 64 69 74 | of Caen|orhabdit|
|00004690| 69 73 20 65 6c 65 67 61 | 6e 73 00 46 65 72 67 75 |is elega|ns.Fergu|
|000046a0| 73 6f 6e 20 45 4c 2c 20 | 53 74 65 72 6e 62 65 72 |son EL, |Sternber|
|000046b0| 67 20 50 57 2c 20 48 6f | 72 76 69 74 7a 20 48 52 |g PW, Ho|rvitz HR|
|000046c0| 00 4e 61 74 75 72 65 00 | 33 32 36 00 32 36 37 00 |.Nature.|326.267.|
|000046d0| 31 39 38 37 00 4a 00 00 | 00 41 64 76 2e 43 26 4d |1987.J..|.Adv.C&M|
|000046e0| 42 3b 45 72 72 6f 72 2f | 45 72 72 61 74 75 6d 2f |B;Error/|Erratum/|
|000046f0| 43 6f 72 72 65 63 74 69 | 6f 6e 3a 4e 61 74 75 72 |Correcti|on:Natur|
|00004700| 65 20 33 32 37 3a 38 32 | 28 31 39 38 37 29 3b 63 |e 327:82|(1987);c|
|00004710| 65 6c 6c 20 66 61 74 65 | 3b 20 63 65 6c 6c 20 6c |ell fate|; cell l|
|00004720| 69 6e 65 61 67 65 3b 63 | 65 6c 6c 20 64 65 74 65 |ineage;c|ell dete|
|00004730| 72 6d 69 6e 61 74 69 6f | 6e 2f 63 6f 6d 6d 69 74 |rminatio|n/commit|
|00004740| 6d 65 6e 74 3b 68 6f 6d | 65 6f 74 69 63 20 74 72 |ment;hom|eotic tr|
|00004750| 61 6e 73 66 6f 72 6d 61 | 74 69 6f 6e 00 07 44 00 |ansforma|tion..D.|
|00004760| 01 3e 20 07 04 08 05 02 | 01 01 00 00 4d 75 74 61 |.> .....|....Muta|
|00004770| 74 69 6f 6e 73 20 61 66 | 66 65 63 74 69 6e 67 20 |tions af|fecting |
|00004780| 73 65 67 6d 65 6e 74 20 | 6e 75 6d 62 65 72 20 61 |segment |number a|
|00004790| 6e 64 20 70 6f 6c 61 72 | 69 74 79 20 69 6e 20 44 |nd polar|ity in D|
|000047a0| 72 6f 73 6f 70 68 69 6c | 61 00 4e 81 73 73 6c 65 |rosophil|a.N.ssle|
|000047b0| 69 6e 2d 56 6f 6c 68 61 | 72 64 20 43 2c 20 57 69 |in-Volha|rd C, Wi|
|000047c0| 65 73 63 68 61 75 73 20 | 45 00 4e 61 74 75 72 65 |eschaus |E.Nature|
|000047d0| 00 32 38 37 00 37 39 35 | 2d 38 30 31 00 31 39 38 |.287.795|-801.198|
|000047e0| 30 00 4a 00 00 00 41 64 | 76 2e 43 26 4d 42 3b 46 |0.J...Ad|v.C&MB;F|
|000047f0| 6c 6f 72 61 20 4b 61 74 | 7a 20 72 65 61 64 69 6e |lora Kat|z readin|
|00004800| 67 73 20 63 6f 75 72 73 | 65 3b 44 72 6f 73 6f 70 |gs cours|e;Drosop|
|00004810| 68 69 6c 61 3b 73 65 67 | 6d 65 6e 74 20 70 6f 6c |hila;seg|ment pol|
|00004820| 61 72 69 74 79 20 67 65 | 6e 65 73 3b 67 61 70 20 |arity ge|nes;gap |
|00004830| 6d 75 74 61 6e 74 73 3b | 70 61 69 72 2d 72 75 6c |mutants;|pair-rul|
|00004840| 65 20 67 65 6e 65 73 3b | 6d 75 74 61 6e 74 20 73 |e genes;|mutant s|
|00004850| 63 72 65 65 6e 3b 70 61 | 74 74 65 72 6e 20 66 6f |creen;pa|ttern fo|
|00004860| 72 6d 61 74 69 6f 6e 00 | 07 45 00 01 25 16 0e 03 |rmation.|.E..%...|
|00004870| 08 05 02 01 29 00 00 47 | 65 6e 65 74 69 63 73 20 |....)..G|enetics |
|00004880| 6f 66 20 44 72 6f 73 6f | 70 68 69 6c 61 20 45 6d |of Droso|phila Em|
|00004890| 62 72 79 6f 67 65 6e 65 | 73 69 73 00 4d 61 68 6f |bryogene|sis.Maho|
|000048a0| 77 61 6c 64 20 41 50 2c | 20 48 61 72 64 79 20 50 |wald AP,| Hardy P|
|000048b0| 41 00 41 6e 6e 20 52 65 | 76 20 47 65 6e 65 74 00 |A.Ann Re|v Genet.|
|000048c0| 31 39 00 31 34 39 2d 31 | 37 37 00 31 39 38 35 00 |19.149-1|77.1985.|
|000048d0| 42 00 00 41 6e 6e 75 61 | 6c 20 52 65 76 69 65 77 |B..Annua|l Review|
|000048e0| 73 2c 20 49 6e 63 2e 2c | 20 50 61 6c 6f 20 41 6c |s, Inc.,| Palo Al|
|000048f0| 74 6f 2c 20 43 41 20 20 | 55 53 41 00 41 64 76 2e |to, CA  |USA.Adv.|
|00004900| 43 26 4d 42 3b 44 72 6f | 73 6f 70 68 69 6c 61 3b |C&MB;Dro|sophila;|
|00004910| 65 6d 62 72 79 6f 67 65 | 6e 65 73 69 73 3b 70 61 |embryoge|nesis;pa|
|00004920| 74 74 65 72 6e 20 66 6f | 72 6d 61 74 69 6f 6e 3b |ttern fo|rmation;|
|00004930| 68 6f 6d 65 6f 74 69 63 | 20 67 65 6e 65 3b 20 6d |homeotic| gene; m|
|00004940| 61 74 65 72 6e 61 6c 20 | 65 66 66 65 63 74 20 67 |aternal |effect g|
|00004950| 65 6e 65 73 3b 7a 79 67 | 6f 74 69 63 20 67 65 6e |enes;zyg|otic gen|
|00004960| 65 73 3b 62 69 74 68 6f | 72 61 78 2f 42 58 3b 61 |es;bitho|rax/BX;a|
|00004970| 6e 74 65 6e 6e 61 70 65 | 64 69 61 2f 41 4e 54 3b |ntennape|dia/ANT;|
|00004980| 52 65 76 69 65 77 00 07 | 46 00 01 5d 29 08 04 08 |Review..|F..])...|
|00004990| 05 02 01 01 00 00 45 78 | 70 72 65 73 73 69 6f 6e |......Ex|pression|
|000049a0| 20 61 6e 64 20 66 75 6e | 63 74 69 6f 6e 20 6f 66 | and fun|ction of|
|000049b0| 20 74 68 65 20 73 65 67 | 6d 65 6e 74 61 74 69 6f | the seg|mentatio|
|000049c0| 6e 20 67 65 6e 65 20 66 | 75 73 68 69 20 74 61 72 |n gene f|ushi tar|
|000049d0| 61 7a 75 20 64 75 72 69 | 6e 67 20 44 72 6f 73 6f |azu duri|ng Droso|
|000049e0| 70 68 69 6c 61 20 6e 65 | 75 72 6f 67 65 6e 65 73 |phila ne|urogenes|
|000049f0| 69 73 00 44 6f 65 20 43 | 51 2c 20 48 69 72 6f 6d |is.Doe C|Q, Hirom|
|00004a00| 69 20 59 2c 20 47 65 68 | 72 69 6e 67 20 57 4a 2c |i Y, Geh|ring WJ,|
|00004a10| 20 47 6f 6f 64 6d 61 6e | 20 43 53 00 53 63 69 65 | Goodman| CS.Scie|
|00004a20| 6e 63 65 00 32 33 39 00 | 31 37 30 2d 31 37 35 00 |nce.239.|170-175.|
|00004a30| 31 39 38 38 00 4a 00 00 | 00 41 64 76 2e 43 26 4d |1988.J..|.Adv.C&M|
|00004a40| 42 3b 44 72 6f 73 6f 70 | 68 69 6c 61 3b 66 74 7a |B;Drosop|hila;ftz|
|00004a50| 2f 66 75 73 68 69 20 74 | 61 72 61 7a 75 20 67 65 |/fushi t|arazu ge|
|00004a60| 6e 65 3b 6e 65 75 72 61 | 6c 20 64 65 76 65 6c 6f |ne;neura|l develo|
|00004a70| 70 6d 65 6e 74 3b 20 63 | 65 6c 6c 20 64 69 66 66 |pment; c|ell diff|
|00004a80| 65 72 65 6e 74 69 61 74 | 69 6f 6e 3b 73 65 67 6d |erentiat|ion;segm|
|00004a90| 65 6e 74 61 74 69 6f 6e | 3b 70 61 74 74 65 72 6e |entation|;pattern|
|00004aa0| 20 66 6f 72 6d 61 74 69 | 6f 6e 3b 63 65 6c 6c 20 | formati|on;cell |
|00004ab0| 66 61 74 65 2f 64 65 74 | 65 72 6d 69 6e 61 74 69 |fate/det|erminati|
|00004ac0| 6f 6e 00 07 47 00 01 77 | 09 07 04 08 05 02 01 01 |on..G..w|........|
|00004ad0| 00 00 4e 65 61 72 2d 72 | 65 63 69 70 72 6f 63 61 |..Near-r|eciproca|
|00004ae0| 6c 20 70 68 65 6e 6f 74 | 79 70 65 73 20 63 61 75 |l phenot|ypes cau|
|00004af0| 73 65 64 20 62 79 20 69 | 6e 61 63 74 69 76 61 74 |sed by i|nactivat|
|00004b00| 69 6f 6e 20 6f 72 20 69 | 6e 64 69 73 63 72 69 6d |ion or i|ndiscrim|
|00004b10| 69 6e 61 74 65 20 65 78 | 70 72 65 73 73 69 6f 6e |inate ex|pression|
|00004b20| 20 6f 66 20 74 68 65 20 | 44 72 6f 73 6f 70 68 69 | of the |Drosophi|
|00004b30| 6c 61 20 73 65 67 6d 65 | 6e 74 61 74 69 6f 6e 20 |la segme|ntation |
|00004b40| 67 65 6e 65 20 66 74 7a | 00 53 74 72 75 68 6c 20 |gene ftz|.Struhl |
|00004b50| 47 00 4e 61 74 75 72 65 | 00 33 31 38 00 36 37 37 |G.Nature|.318.677|
|00004b60| 2d 36 38 30 00 31 39 38 | 35 00 4a 00 00 00 41 64 |-680.198|5.J...Ad|
|00004b70| 76 2e 43 26 4d 42 3b 44 | 72 6f 73 6f 70 68 69 6c |v.C&MB;D|rosophil|
|00004b80| 61 3b 73 65 67 6d 65 6e | 74 61 74 69 6f 6e 3b 66 |a;segmen|tation;f|
|00004b90| 74 7a 2f 66 75 73 68 69 | 20 74 61 72 61 7a 75 3b |tz/fushi| tarazu;|
|00004ba0| 68 65 61 74 20 73 68 6f | 63 6b 20 70 72 6f 6d 6f |heat sho|ck promo|
|00004bb0| 74 65 72 3b 70 61 69 72 | 2d 72 75 6c 65 20 70 68 |ter;pair|-rule ph|
|00004bc0| 65 6e 6f 74 79 70 65 20 | 69 6e 76 65 72 73 65 3b |enotype |inverse;|
|00004bd0| 61 6c 74 65 72 6e 61 74 | 69 6e 67 20 73 65 67 6d |alternat|ing segm|
|00004be0| 65 6e 74 73 3b 67 65 6e | 65 20 65 78 70 72 65 73 |ents;gen|e expres|
|00004bf0| 73 69 6f 6e 00 07 48 00 | 01 49 15 05 03 06 05 02 |sion..H.|.I......|
|00004c00| 01 01 00 00 4c 6f 63 61 | 6c 69 7a 61 74 69 6f 6e |....Loca|lization|
|00004c10| 20 6f 66 20 74 68 65 20 | 66 75 73 68 69 20 74 61 | of the |fushi ta|
|00004c20| 72 61 7a 75 20 70 72 6f | 74 65 69 6e 20 64 75 72 |razu pro|tein dur|
|00004c30| 69 6e 67 20 44 72 6f 73 | 6f 70 68 69 6c 61 20 65 |ing Dros|ophila e|
|00004c40| 6d 62 72 79 6f 67 65 6e | 65 73 69 73 00 43 61 72 |mbryogen|esis.Car|
|00004c50| 72 6f 6c 6c 20 53 42 2c | 20 53 63 6f 74 74 20 4d |roll SB,| Scott M|
|00004c60| 50 00 43 65 6c 6c 00 34 | 33 00 34 37 2d 35 37 00 |P.Cell.4|3.47-57.|
|00004c70| 31 39 38 35 00 4a 00 00 | 00 41 64 76 2e 43 26 4d |1985.J..|.Adv.C&M|
|00004c80| 42 3b 44 72 6f 73 6f 70 | 68 69 6c 61 3b 66 74 7a |B;Drosop|hila;ftz|
|00004c90| 2f 66 75 73 68 69 20 74 | 61 72 61 7a 75 20 67 65 |/fushi t|arazu ge|
|00004ca0| 6e 65 3b 65 6d 62 72 79 | 6f 67 65 6e 65 73 69 73 |ne;embry|ogenesis|
|00004cb0| 3b 70 72 6f 74 65 69 6e | 20 6c 6f 63 61 6c 69 7a |;protein| localiz|
|00004cc0| 61 74 69 6f 6e 3b 67 65 | 6e 65 20 65 78 70 72 65 |ation;ge|ne expre|
|00004cd0| 73 73 69 6f 6e 3b 66 75 | 73 69 6f 6e 20 70 72 6f |ssion;fu|sion pro|
|00004ce0| 74 65 69 6e 3b 73 65 67 | 6d 65 6e 74 61 74 69 6f |tein;seg|mentatio|
|00004cf0| 6e 00 07 49 00 01 79 55 | 54 01 08 05 02 01 13 00 |n..I..yU|T.......|
|00004d00| 00 45 78 74 72 61 63 65 | 6c 6c 75 6c 61 72 20 6d |.Extrace|llular m|
|00004d10| 61 74 72 69 78 20 72 65 | 67 75 6c 61 74 69 6f 6e |atrix re|gulation|
|00004d20| 20 6f 66 20 63 65 6c 6c | 2d 63 65 6c 6c 20 63 6f | of cell|-cell co|
|00004d30| 6d 6d 75 6e 69 63 61 74 | 69 6f 6e 20 61 6e 64 20 |mmunicat|ion and |
|00004d40| 74 69 73 73 75 65 2d 73 | 70 65 63 69 66 69 63 20 |tissue-s|pecific |
|00004d50| 67 65 6e 65 20 65 78 70 | 72 65 73 73 69 6f 6e 20 |gene exp|ression |
|00004d60| 69 6e 20 70 72 69 6d 61 | 72 79 20 6c 69 76 65 72 |in prima|ry liver|
|00004d70| 20 63 75 6c 74 75 72 65 | 73 00 46 75 6a 69 74 61 | culture|s.Fujita|
|00004d80| 20 4d 2c 20 53 70 72 61 | 79 20 44 43 2c 20 43 68 | M, Spra|y DC, Ch|
|00004d90| 6f 69 20 48 2c 20 53 61 | 65 7a 20 4a 2c 20 4a 65 |oi H, Sa|ez J, Je|
|00004da0| 66 66 65 72 73 6f 6e 20 | 44 4d 2c 20 48 65 72 74 |fferson |DM, Hert|
|00004db0| 7a 62 65 72 67 20 45 2c | 20 52 6f 73 65 6e 62 65 |zberg E,| Rosenbe|
|00004dc0| 72 66 20 4c 43 2c 20 52 | 65 69 64 20 4c 4d 00 43 |rf LC, R|eid LM.C|
|00004dd0| 65 6c 6c 75 6c 61 72 20 | 45 6e 64 6f 63 72 69 6e |ellular |Endocrin|
|00004de0| 6f 6c 6f 67 79 3a 20 20 | 48 6f 72 6d 6f 6e 61 6c |ology:  |Hormonal|
|00004df0| 20 43 6f 6e 74 72 6f 6c | 20 6f 66 20 45 6d 62 72 | Control| of Embr|
|00004e00| 79 6f 6e 69 63 20 61 6e | 64 20 43 65 6c 6c 75 6c |yonic an|d Cellul|
|00004e10| 61 72 20 44 69 66 66 65 | 72 65 6e 74 69 61 74 69 |ar Diffe|rentiati|
|00004e20| 6f 6e 00 00 33 33 33 2d | 33 36 30 00 31 39 38 36 |on..333-|360.1986|
|00004e30| 00 42 00 00 41 6c 61 6e | 20 52 2e 20 4c 69 73 73 |.B..Alan| R. Liss|
|00004e40| 2c 20 49 6e 63 2e 00 41 | 64 76 2e 43 26 4d 42 3b |, Inc..A|dv.C&MB;|
|00004e50| 45 43 4d 2f 65 78 74 72 | 61 63 65 6c 6c 75 6c 61 |ECM/extr|acellula|
|00004e60| 72 20 6d 61 74 72 69 78 | 3b 74 69 73 73 75 65 2d |r matrix|;tissue-|
|00004e70| 73 70 65 63 69 66 69 63 | 20 67 65 6e 65 20 65 78 |specific| gene ex|
|00004e80| 70 72 65 73 73 69 6f 6e | 3b 20 70 72 69 6d 61 72 |pression|; primar|
|00004e90| 79 20 63 75 6c 74 75 72 | 65 3b 63 65 6c 6c 20 64 |y cultur|e;cell d|
|00004ea0| 69 66 66 65 72 65 6e 74 | 69 61 74 69 6f 6e 3b 6c |ifferent|iation;l|
|00004eb0| 69 76 65 72 3b 70 72 6f | 74 65 6f 67 6c 79 63 61 |iver;pro|teoglyca|
|00004ec0| 6e 3b 67 61 70 20 6a 75 | 6e 63 74 69 6f 6e 73 00 |n;gap ju|nctions.|
|00004ed0| 07 4a 00 01 57 16 41 01 | 08 05 02 01 13 00 00 44 |.J..W.A.|.......D|
|00004ee0| 79 6e 61 6d 69 63 20 72 | 65 63 69 70 72 6f 63 69 |ynamic r|eciproci|
|00004ef0| 74 79 3a 20 20 48 6f 77 | 20 64 6f 20 65 78 74 72 |ty:  How| do extr|
|00004f00| 61 63 65 6c 6c 75 6c 61 | 72 20 6d 61 74 72 69 78 |acellula|r matrix|
|00004f10| 20 61 6e 64 20 68 6f 72 | 6d 6f 6e 65 73 20 64 69 | and hor|mones di|
|00004f20| 72 65 63 74 20 67 65 6e | 65 20 65 78 70 72 65 73 |rect gen|e expres|
|00004f30| 73 69 6f 6e 3f 00 42 69 | 73 73 65 6c 6c 20 4d 4a |sion?.Bi|ssell MJ|
|00004f40| 2c 20 41 67 67 65 6c 65 | 72 20 4a 00 4d 65 63 68 |, Aggele|r J.Mech|
|00004f50| 61 6e 69 73 6d 73 20 6f | 66 20 53 69 67 6e 61 6c |anisms o|f Signal|
|00004f60| 20 54 72 61 6e 73 64 75 | 63 74 69 6f 6e 20 62 79 | Transdu|ction by|
|00004f70| 20 48 6f 72 6d 6f 6e 65 | 73 20 61 6e 64 20 47 72 | Hormone|s and Gr|
|00004f80| 6f 77 74 68 20 46 61 63 | 74 6f 72 73 00 00 32 35 |owth Fac|tors..25|
|00004f90| 31 2d 32 36 32 00 31 39 | 38 37 00 42 00 00 41 6c |1-262.19|87.B..Al|
|00004fa0| 61 6e 20 52 2e 20 4c 69 | 73 73 2c 20 49 6e 63 2e |an R. Li|ss, Inc.|
|00004fb0| 00 41 64 76 2e 43 26 4d | 42 3b 45 43 4d 2f 65 78 |.Adv.C&M|B;ECM/ex|
|00004fc0| 74 72 61 63 65 6c 6c 75 | 6c 61 72 20 6d 61 74 72 |tracellu|lar matr|
|00004fd0| 69 78 3b 67 65 6e 65 20 | 65 78 70 72 65 73 73 69 |ix;gene |expressi|
|00004fe0| 6f 6e 3b 68 6f 72 6d 6f | 6e 65 73 3b 6d 6f 75 73 |on;hormo|nes;mous|
|00004ff0| 65 3b 20 63 65 6c 6c 20 | 73 68 61 70 65 3b 63 65 |e; cell |shape;ce|
|00005000| 6c 6c 20 70 6f 6c 61 72 | 69 74 79 3b 63 79 74 6f |ll polar|ity;cyto|
|00005010| 73 6b 65 6c 65 74 6f 6e | 3b 6e 75 63 6c 65 61 72 |skeleton|;nuclear|
|00005020| 20 6d 61 74 72 69 78 3b | 74 72 61 6e 73 6d 65 6d | matrix;|transmem|
|00005030| 62 72 61 6e 65 20 70 72 | 6f 74 65 69 6e 73 00 07 |brane pr|oteins..|
|00005040| 4b 00 01 6a 15 17 03 0a | 05 02 01 01 00 00 4d 65 |K..j....|......Me|
|00005050| 74 61 6c 6c 6f 65 6e 64 | 6f 70 72 6f 74 65 61 73 |talloend|oproteas|
|00005060| 65 20 69 6e 68 69 62 69 | 74 6f 72 73 20 74 68 61 |e inhibi|tors tha|
|00005070| 74 20 62 6c 6f 63 6b 20 | 66 75 73 69 6f 6e 20 61 |t block |fusion a|
|00005080| 6c 73 6f 20 70 72 65 76 | 65 6e 74 20 62 69 6f 63 |lso prev|ent bioc|
|00005090| 68 65 6d 69 63 61 6c 20 | 64 69 66 66 65 72 65 6e |hemical |differen|
|000050a0| 74 69 61 74 69 6f 6e 20 | 69 6e 20 4c 36 20 6d 79 |tiation |in L6 my|
|000050b0| 6f 62 6c 61 73 74 73 00 | 42 61 6c 64 77 69 6e 20 |oblasts.|Baldwin |
|000050c0| 45 2c 20 4b 61 79 61 6c | 61 72 20 43 00 50 72 6f |E, Kayal|ar C.Pro|
|000050d0| 63 20 4e 61 74 6c 20 41 | 63 61 64 20 53 63 69 20 |c Natl A|cad Sci |
|000050e0| 55 53 41 00 38 33 00 38 | 30 32 39 2d 38 30 33 33 |USA.83.8|029-8033|
|000050f0| 00 31 39 38 36 00 4a 00 | 00 00 42 69 6c 6c 20 53 |.1986.J.|..Bill S|
|00005100| 6e 65 6c 6c 20 72 65 61 | 64 69 6e 67 73 20 63 6f |nell rea|dings co|
|00005110| 75 72 73 65 3b 6d 79 6f | 62 6c 61 73 74 20 66 75 |urse;myo|blast fu|
|00005120| 73 69 6f 6e 3b 4c 36 20 | 63 65 6c 6c 73 3b 72 61 |sion;L6 |cells;ra|
|00005130| 74 3b 20 70 68 65 6e 61 | 6e 74 68 72 6f 6c 69 6e |t; phena|nthrolin|
|00005140| 65 3b 6d 65 74 61 6c 6c | 6f 65 6e 64 6f 70 72 6f |e;metall|oendopro|
|00005150| 74 65 61 73 65 20 69 6e | 68 69 62 69 74 6f 72 73 |tease in|hibitors|
|00005160| 3b 64 69 66 66 65 72 65 | 6e 74 69 61 74 69 6f 6e |;differe|ntiation|
|00005170| 20 62 6c 6f 63 6b 00 07 | 00 00 01 35 21 05 03 04 | block..|...5!...|
|00005180| 05 02 01 01 00 00 45 6e | 7a 79 6d 61 74 69 63 20 |......En|zymatic |
|00005190| 52 65 63 79 63 6c 69 6e | 67 20 6f 66 20 43 6c 61 |Recyclin|g of Cla|
|000051a0| 74 68 72 69 6e 20 66 72 | 6f 6d 20 43 6f 61 74 65 |thrin fr|om Coate|
|000051b0| 64 20 56 65 73 69 63 6c | 65 73 00 52 6f 74 68 6d |d Vesicl|es.Rothm|
|000051c0| 61 6e 20 4a 61 6d 65 73 | 20 45 2c 20 53 63 68 6d |an James| E, Schm|
|000051d0| 69 64 20 53 61 6e 64 72 | 61 20 4c 00 43 65 6c 6c |id Sandr|a L.Cell|
|000051e0| 00 34 36 00 35 2d 39 00 | 31 39 38 36 00 4a 00 00 |.46.5-9.|1986.J..|
|000051f0| 00 52 65 76 69 65 77 3b | 20 43 6c 61 74 68 72 69 |.Review;| Clathri|
|00005200| 6e 20 72 65 63 79 63 6c | 69 6e 67 3b 20 63 6f 61 |n recycl|ing; coa|
|00005210| 74 65 64 20 76 65 73 69 | 63 6c 65 20 72 65 63 79 |ted vesi|cle recy|
|00005220| 63 6c 69 6e 67 3b 20 41 | 54 50 61 73 65 3b 20 55 |cling; A|TPase; U|
|00005230| 6e 63 6f 61 74 69 6e 67 | 20 70 72 6f 74 65 69 6e |ncoating| protein|
|00005240| 00 07 00 00 01 4c 47 18 | 03 08 05 02 01 01 00 00 |.....LG.|........|
|00005250| 41 6e 20 45 6e 7a 79 6d | 65 20 74 68 61 74 20 52 |An Enzym|e that R|
|00005260| 65 6d 6f 76 65 73 20 43 | 6c 61 74 68 72 69 6e 20 |emoves C|lathrin |
|00005270| 43 6f 61 74 73 3a 20 20 | 50 75 72 69 66 69 63 61 |Coats:  |Purifica|
|00005280| 74 69 6f 6e 20 6f 66 20 | 61 6e 20 55 6e 63 6f 61 |tion of |an Uncoa|
|00005290| 74 69 6e 67 20 41 54 50 | 61 73 65 00 53 63 68 6c |ting ATP|ase.Schl|
|000052a0| 6f 73 73 6d 61 6e 20 44 | 61 76 69 64 20 4d 2c 20 |ossman D|avid M, |
|000052b0| 53 63 68 6d 69 64 20 53 | 61 6e 64 72 61 20 4c 2c |Schmid S|andra L,|
|000052c0| 20 42 72 61 65 6c 6c 20 | 57 69 6c 6c 69 61 6d 20 | Braell |William |
|000052d0| 41 2c 20 52 6f 74 68 6d | 61 6e 20 4a 61 6d 65 73 |A, Rothm|an James|
|000052e0| 20 45 00 4a 6f 75 72 6e | 61 6c 20 6f 66 20 43 65 | E.Journ|al of Ce|
|000052f0| 6c 6c 20 42 69 6f 6c 6f | 67 79 00 39 39 00 37 32 |ll Biolo|gy.99.72|
|00005300| 33 2d 37 33 33 00 31 39 | 38 34 00 4a 00 00 00 55 |3-733.19|84.J...U|
|00005310| 6e 63 6f 61 74 69 6e 67 | 20 41 54 50 61 73 65 3b |ncoating| ATPase;|
|00005320| 20 43 6f 61 74 65 64 20 | 56 65 73 69 63 6c 65 73 | Coated |Vesicles|
|00005330| 3b 20 43 6c 61 74 68 72 | 69 6e 3b 20 54 72 69 73 |; Clathr|in; Tris|
|00005340| 6b 65 6c 69 6f 6e 73 00 | 07 00 00 01 5e 47 18 03 |kelions.|....^G..|
|00005350| 08 05 02 01 01 00 00 44 | 69 73 73 6f 63 69 61 74 |.......D|issociat|
|00005360| 69 6f 6e 20 6f 66 20 63 | 6c 61 74 68 72 69 6e 20 |ion of c|lathrin |
|00005370| 63 6f 61 74 73 20 63 6f | 75 70 6c 65 64 20 74 6f |coats co|upled to|
|00005380| 20 74 68 65 20 68 79 64 | 72 6f 6c 79 73 69 73 20 | the hyd|rolysis |
|00005390| 6f 66 20 41 54 50 3a 20 | 20 52 6f 6c 65 20 6f 66 |of ATP: | Role of|
|000053a0| 20 61 6e 20 75 6e 63 6f | 61 74 69 6e 67 20 41 54 | an unco|ating AT|
|000053b0| 50 61 73 65 00 42 72 61 | 65 6c 6c 20 57 69 6c 6c |Pase.Bra|ell Will|
|000053c0| 69 61 6d 20 41 2c 20 53 | 63 68 6c 6f 73 73 6d 61 |iam A, S|chlossma|
|000053d0| 6e 20 44 61 76 69 64 20 | 4d 2c 20 53 63 68 6d 69 |n David |M, Schmi|
|000053e0| 64 20 53 61 6e 64 72 61 | 20 4c 2c 20 52 6f 74 68 |d Sandra| L, Roth|
|000053f0| 6d 61 6e 20 4a 61 6d 65 | 73 20 45 00 4a 6f 75 72 |man Jame|s E.Jour|
|00005400| 6e 61 6c 20 6f 66 20 43 | 65 6c 6c 20 42 69 6f 6c |nal of C|ell Biol|
|00005410| 6f 67 79 00 39 39 00 37 | 33 34 2d 37 34 31 00 31 |ogy.99.7|34-741.1|
|00005420| 39 38 34 00 4a 00 00 00 | 55 6e 63 6f 61 74 69 6e |984.J...|Uncoatin|
|00005430| 67 20 41 54 50 61 73 65 | 3b 20 43 6c 61 74 68 72 |g ATPase|; Clathr|
|00005440| 69 6e 20 75 6e 63 6f 61 | 74 69 6e 67 3b 00 07 00 |in uncoa|ting;...|
|00005450| 00 01 40 21 0c 04 0c 05 | 02 01 01 00 00 45 6e 7a |..@!....|.....Enz|
|00005460| 79 6d 61 74 69 63 20 64 | 69 73 73 6f 63 69 61 74 |ymatic d|issociat|
|00005470| 69 6f 6e 20 6f 66 20 63 | 6c 61 74 68 72 69 6e 20 |ion of c|lathrin |
|00005480| 63 61 67 65 73 20 69 6e | 20 61 20 74 77 6f 2d 73 |cages in| a two-s|
|00005490| 74 61 67 65 20 70 72 6f | 63 65 73 73 00 53 63 68 |tage pro|cess.Sch|
|000054a0| 6d 69 64 20 53 61 6e 64 | 72 61 20 4c 2c 20 52 6f |mid Sand|ra L, Ro|
|000054b0| 74 68 6d 61 6e 20 4a 61 | 6d 65 73 20 45 00 4a 20 |thman Ja|mes E.J |
|000054c0| 42 69 6f 6c 20 43 68 65 | 6d 00 32 36 30 00 31 30 |Biol Che|m.260.10|
|000054d0| 30 34 34 2d 31 30 30 34 | 39 00 31 39 38 35 00 4a |044-1004|9.1985.J|
|000054e0| 00 00 00 55 6e 63 6f 61 | 74 69 6e 67 20 41 54 50 |...Uncoa|ting ATP|
|000054f0| 61 73 65 3b 20 43 6c 61 | 74 68 72 69 6e 00 07 00 |ase; Cla|thrin...|
|00005500| 00 01 4b 21 0c 04 0c 05 | 02 01 01 00 00 54 77 6f |..K!....|.....Two|
|00005510| 20 63 6c 61 73 73 65 73 | 20 6f 66 20 62 69 6e 64 | classes| of bind|
|00005520| 69 6e 67 20 73 69 74 65 | 73 20 66 6f 72 20 75 6e |ing site|s for un|
|00005530| 63 6f 61 74 69 6e 67 20 | 70 72 6f 74 65 69 6e 20 |coating |protein |
|00005540| 69 6e 20 63 6c 61 74 68 | 72 69 6e 20 74 72 69 73 |in clath|rin tris|
|00005550| 6b 65 6c 69 6f 6e 73 00 | 53 63 68 6d 69 64 20 53 |kelions.|Schmid S|
|00005560| 61 6e 64 72 61 20 4c 2c | 20 52 6f 74 68 6d 61 6e |andra L,| Rothman|
|00005570| 20 4a 61 6d 65 73 20 45 | 00 4a 20 42 69 6f 6c 20 | James E|.J Biol |
|00005580| 43 68 65 6d 00 32 36 30 | 00 31 30 30 35 30 2d 31 |Chem.260|.10050-1|
|00005590| 30 30 35 36 00 31 39 38 | 35 00 4a 00 00 00 55 6e |0056.198|5.J...Un|
|000055a0| 63 6f 61 74 69 6e 67 20 | 41 54 50 61 73 65 3b 20 |coating |ATPase; |
|000055b0| 43 6c 61 74 68 72 69 6e | 00 07 00 00 01 47 33 0c |Clathrin|.....G3.|
|000055c0| 04 0c 05 02 01 01 00 00 | 41 54 50 20 63 61 74 61 |........|ATP cata|
|000055d0| 6c 79 7a 65 73 20 74 68 | 65 20 73 65 71 75 65 73 |lyzes th|e seques|
|000055e0| 74 72 61 74 69 6f 6e 20 | 6f 66 20 63 6c 61 74 68 |tration |of clath|
|000055f0| 72 69 6e 20 64 75 72 69 | 6e 67 20 65 6e 7a 79 6d |rin duri|ng enzym|
|00005600| 61 74 69 63 20 75 6e 63 | 6f 61 74 69 6e 67 00 53 |atic unc|oating.S|
|00005610| 63 68 6d 69 64 20 53 61 | 6e 64 72 61 20 4c 2c 20 |chmid Sa|ndra L, |
|00005620| 42 72 61 65 6c 6c 20 57 | 69 6c 6c 69 61 6d 20 41 |Braell W|illiam A|
|00005630| 2c 20 52 6f 74 68 6d 61 | 6e 20 4a 61 6d 65 73 20 |, Rothma|n James |
|00005640| 45 00 4a 20 42 69 6f 6c | 20 43 68 65 6d 00 32 36 |E.J Biol| Chem.26|
|00005650| 30 00 31 30 30 35 37 2d | 31 30 30 36 32 00 31 39 |0.10057-|10062.19|
|00005660| 38 35 00 4a 00 00 00 55 | 6e 63 6f 61 74 69 6e 67 |85.J...U|ncoating|
|00005670| 20 41 54 50 61 73 65 3b | 20 43 6c 61 74 68 72 69 | ATPase;| Clathri|
|00005680| 6e 00 07 52 00 01 2b 09 | 13 02 06 05 02 01 01 00 |n..R..+.|........|
|00005690| 00 49 6e 65 72 74 69 61 | 20 6f 66 20 74 68 65 20 |.Inertia| of the |
|000056a0| 65 6d 62 72 79 6f 6e 69 | 63 20 67 65 6e 6f 6d 65 |embryoni|c genome|
|000056b0| 20 69 6e 20 6d 61 6d 6d | 61 6c 73 00 53 6f 6c 74 | in mamm|als.Solt|
|000056c0| 65 72 20 44 00 54 72 65 | 6e 64 73 20 69 6e 20 47 |er D.Tre|nds in G|
|000056d0| 65 6e 65 74 69 63 73 00 | 33 00 32 33 2d 32 37 00 |enetics.|3.23-27.|
|000056e0| 31 39 38 37 00 4a 00 00 | 00 4d 6f 75 73 65 20 65 |1987.J..|.Mouse e|
|000056f0| 6d 62 72 79 6f 67 65 6e | 65 73 69 73 3b 20 73 68 |mbryogen|esis; sh|
|00005700| 65 65 70 20 65 6d 62 72 | 79 6f 67 65 6e 65 73 69 |eep embr|yogenesi|
|00005710| 73 3b 20 6d 61 6d 6d 61 | 6c 69 61 6e 20 64 65 76 |s; mamma|lian dev|
|00005720| 65 6c 6f 70 6d 65 6e 74 | 3b 20 6e 75 63 6c 65 61 |elopment|; nuclea|
|00005730| 72 20 74 72 61 6e 73 66 | 65 72 3b 20 61 6e 64 72 |r transf|er; andr|
|00005740| 6f 67 65 6e 65 74 69 63 | 2f 67 79 6e 6f 67 65 6e |ogenetic|/gynogen|
|00005750| 65 74 69 63 20 65 6d 62 | 72 79 6f 73 3b 20 63 68 |etic emb|ryos; ch|
|00005760| 72 6f 6d 6f 73 6f 6d 65 | 20 6d 61 70 70 69 6e 67 |romosome| mapping|
|00005770| 00 69 6e 67 00 07 53 00 | 01 a2 30 1f 09 08 05 02 |.ing..S.|..0.....|
|00005780| 01 01 00 00 41 20 35 27 | 2d 66 6c 61 6e 6b 69 6e |....A 5'|-flankin|
|00005790| 67 20 72 65 67 69 6f 6e | 20 6f 66 20 74 68 65 20 |g region| of the |
|000057a0| 63 68 69 63 6b 65 6e 20 | 61 63 65 74 79 6c 63 68 |chicken |acetylch|
|000057b0| 6f 6c 69 6e 65 20 72 65 | 63 65 70 74 6f 72 20 e0 |oline re|ceptor .|
|000057c0| 2d 73 75 62 75 6e 69 74 | 20 67 65 6e 65 20 63 6f |-subunit| gene co|
|000057d0| 6e 66 65 72 73 20 74 69 | 73 73 75 65 20 73 70 65 |nfers ti|ssue spe|
|000057e0| 63 69 66 69 63 69 74 79 | 20 61 6e 64 20 64 65 76 |cificity| and dev|
|000057f0| 65 6c 6f 70 6d 65 6e 74 | 61 6c 20 63 6f 6e 74 72 |elopment|al contr|
|00005800| 6f 6c 20 6f 66 20 65 78 | 70 72 65 73 73 69 6f 6e |ol of ex|pression|
|00005810| 20 69 6e 20 74 72 61 6e | 73 66 65 63 74 65 64 20 | in tran|sfected |
|00005820| 63 65 6c 6c 73 00 4b 6c | 61 72 73 66 65 6c 64 20 |cells.Kl|arsfeld |
|00005830| 41 2c 20 44 61 75 62 61 | 73 20 50 2c 20 42 6f 75 |A, Dauba|s P, Bou|
|00005840| 72 61 63 68 6f 74 20 42 | 2c 20 43 68 61 6e 67 65 |rachot B|, Change|
|00005850| 75 78 20 4a 50 00 4d 6f | 6c 65 63 75 6c 61 72 20 |ux JP.Mo|lecular |
|00005860| 61 6e 64 20 43 65 6c 6c | 75 6c 61 72 20 42 69 6f |and Cell|ular Bio|
|00005870| 6c 6f 67 79 00 37 2c 20 | 4e 6f 2e 20 32 00 39 35 |logy.7, |No. 2.95|
|00005880| 31 2d 39 35 35 00 31 39 | 38 37 00 4a 00 00 00 54 |1-955.19|87.J...T|
|00005890| 41 54 41 20 43 41 41 54 | 20 62 6f 78 65 73 3b 20 |ATA CAAT| boxes; |
|000058a0| 53 70 31 20 62 69 6e 64 | 69 6e 67 20 73 69 74 65 |Sp1 bind|ing site|
|000058b0| 3b 20 6d 75 73 63 6c 65 | 20 61 63 65 74 79 6c 63 |; muscle| acetylc|
|000058c0| 68 6f 6c 69 6e 65 20 72 | 65 63 65 70 74 6f 72 3b |holine r|eceptor;|
|000058d0| 20 43 41 54 20 61 73 73 | 61 79 3b 20 74 72 61 6e | CAT ass|ay; tran|
|000058e0| 73 66 65 63 74 69 6f 6e | 3b 20 6d 79 6f 74 75 62 |sfection|; myotub|
|000058f0| 65 73 3b 20 6d 79 6f 62 | 6c 61 73 74 73 00 07 54 |es; myob|lasts..T|
|00005900| 00 01 4a 21 05 03 09 05 | 02 01 01 00 00 45 78 70 |..J!....|.....Exp|
|00005910| 72 65 73 73 69 6f 6e 20 | 6f 66 20 61 20 73 69 6e |ression |of a sin|
|00005920| 67 6c 65 20 74 72 61 6e | 73 66 65 63 74 65 64 20 |gle tran|sfected |
|00005930| 63 44 4e 41 20 63 6f 6e | 76 65 72 74 73 20 66 69 |cDNA con|verts fi|
|00005940| 62 72 6f 62 6c 61 73 74 | 73 20 74 6f 20 6d 79 6f |broblast|s to myo|
|00005950| 62 6c 61 73 74 73 00 44 | 61 76 69 73 20 52 4c 2c |blasts.D|avis RL,|
|00005960| 20 57 65 69 6e 74 72 61 | 75 62 20 48 2c 20 4c 61 | Weintra|ub H, La|
|00005970| 73 73 61 72 20 41 42 00 | 43 65 6c 6c 00 35 31 00 |ssar AB.|Cell.51.|
|00005980| 39 38 37 2d 31 30 30 30 | 00 31 39 38 37 00 4a 00 |987-1000|.1987.J.|
|00005990| 00 00 4d 79 6f 67 65 6e | 65 73 69 73 3b 20 63 6f |..Myogen|esis; co|
|000059a0| 6d 6d 69 74 6d 65 6e 74 | 3b 20 4d 79 6f 44 31 3b |mmitment|; MyoD1;|
|000059b0| 20 43 33 48 31 30 54 31 | 2f 32 20 63 65 6c 6c 73 | C3H10T1|/2 cells|
|000059c0| 3b 20 35 2d 61 7a 61 63 | 79 74 69 64 69 6e 65 3b |; 5-azac|ytidine;|
|000059d0| 20 73 75 62 74 72 61 63 | 74 69 76 65 20 68 79 62 | subtrac|tive hyb|
|000059e0| 72 69 64 69 7a 61 74 69 | 6f 6e 3b 20 63 2d 6d 79 |ridizati|on; c-my|
|000059f0| 63 20 70 72 6f 74 65 69 | 6e 20 68 6f 6d 6f 6c 6f |c protei|n homolo|
|00005a00| 67 79 3b 20 7a 69 6e 63 | 20 66 69 6e 67 65 72 73 |gy; zinc| fingers|
|00005a10| 3b 20 44 4e 41 20 62 69 | 6e 64 69 6e 67 00 07 55 |; DNA bi|nding..U|
|00005a20| 00 01 43 14 0c 04 0a 05 | 02 01 01 00 00 54 77 6f |..C.....|.....Two|
|00005a30| 20 6e 75 63 6c 65 61 72 | 20 66 61 63 74 6f 72 73 | nuclear| factors|
|00005a40| 20 63 6f 6d 70 65 74 65 | 20 66 6f 72 20 74 68 65 | compete| for the|
|00005a50| 20 73 6b 65 6c 65 74 61 | 6c 20 6d 75 73 63 6c 65 | skeleta|l muscle|
|00005a60| 20 61 63 74 69 6e 20 70 | 72 6f 6d 6f 74 65 72 00 | actin p|romoter.|
|00005a70| 57 61 6c 73 68 20 4b 2c | 20 53 63 68 69 6d 6d 65 |Walsh K,| Schimme|
|00005a80| 6c 20 50 00 4a 20 42 69 | 6f 6c 20 43 68 65 6d 00 |l P.J Bi|ol Chem.|
|00005a90| 32 36 32 00 39 34 32 39 | 2d 39 34 33 32 00 31 39 |262.9429|-9432.19|
|00005aa0| 38 37 00 4a 00 00 00 4d | 79 6f 67 65 6e 65 73 69 |87.J...M|yogenesi|
|00005ab0| 73 3b 20 74 72 61 6e 73 | 2d 61 63 74 69 6e 67 20 |s; trans|-acting |
|00005ac0| 66 61 63 74 6f 72 73 3b | 20 6d 79 6f 67 65 6e 69 |factors;| myogeni|
|00005ad0| 63 20 64 69 66 66 65 72 | 65 6e 74 69 61 74 69 6f |c differ|entiatio|
|00005ae0| 6e 3b 20 6d 75 73 63 6c | 65 20 63 65 6c 6c 20 64 |n; muscl|e cell d|
|00005af0| 69 66 66 65 72 65 6e 74 | 69 61 74 69 6f 6e 00 07 |ifferent|iation..|
|00005b00| 56 00 01 5f 0e 17 03 07 | 05 02 1b 27 00 00 41 63 |V.._....|...'..Ac|
|00005b10| 74 69 6e 20 61 6e 64 20 | 6d 79 6f 73 69 6e 20 6d |tin and |myosin m|
|00005b20| 75 6c 74 69 67 65 6e 65 | 20 66 61 6d 69 6c 69 65 |ultigene| familie|
|00005b30| 73 3a 20 20 54 68 65 69 | 72 20 65 78 70 72 65 73 |s:  Thei|r expres|
|00005b40| 73 69 6f 6e 20 64 75 72 | 69 6e 67 20 74 68 65 20 |sion dur|ing the |
|00005b50| 66 6f 72 6d 61 74 69 6f | 6e 20 6f 66 20 73 6b 65 |formatio|n of ske|
|00005b60| 6c 65 74 61 6c 20 6d 75 | 73 63 6c 65 00 42 75 63 |letal mu|scle.Buc|
|00005b70| 6b 69 6e 67 68 61 6d 20 | 4d 45 00 45 73 73 61 79 |kingham |ME.Essay|
|00005b80| 73 20 69 6e 20 42 69 6f | 63 68 65 6d 69 73 74 72 |s in Bio|chemistr|
|00005b90| 79 00 32 30 00 37 37 2d | 31 30 39 00 31 39 38 35 |y.20.77-|109.1985|
|00005ba0| 00 42 00 43 61 6d 70 62 | 65 6c 6c 20 61 6e 64 20 |.B.Campb|ell and |
|00005bb0| 4d 61 72 73 68 61 6c 6c | 20 3f 3f 3f 3f 00 54 68 |Marshall| ????.Th|
|00005bc0| 65 20 42 69 6f 63 68 65 | 6d 69 63 61 6c 20 53 6f |e Bioche|mical So|
|00005bd0| 63 69 65 74 79 2f 41 63 | 61 64 65 6d 69 63 20 50 |ciety/Ac|ademic P|
|00005be0| 72 65 73 73 00 61 63 74 | 69 6e 20 67 65 6e 65 73 |ress.act|in genes|
|00005bf0| 3b 20 6d 79 6f 73 69 6e | 20 67 65 6e 65 73 3b 20 |; myosin| genes; |
|00005c00| 6d 79 6f 67 65 6e 65 73 | 69 73 3b 20 72 65 76 69 |myogenes|is; revi|
|00005c10| 65 77 3b 20 67 65 6e 65 | 20 74 72 61 6e 73 63 72 |ew; gene| transcr|
|00005c20| 69 70 74 69 6f 6e 3b 20 | 6d 75 6c 74 69 67 65 6e |iption; |multigen|
|00005c30| 65 20 66 61 6d 69 6c 79 | 3b 20 67 65 6e 65 20 73 |e family|; gene s|
|00005c40| 77 69 74 63 68 69 6e 67 | 00 07 57 00 01 77 2b 14 |witching|..W..w+.|
|00005c50| 02 08 05 02 01 01 00 00 | 4d 75 73 63 6c 65 20 63 |........|Muscle c|
|00005c60| 65 6c 6c 20 63 6f 6d 70 | 6f 6e 65 6e 74 73 20 64 |ell comp|onents d|
|00005c70| 69 63 74 61 74 65 20 68 | 65 70 61 74 6f 63 79 74 |ictate h|epatocyt|
|00005c80| 65 20 67 65 6e 65 20 65 | 78 70 72 65 73 73 69 6f |e gene e|xpressio|
|00005c90| 6e 20 61 6e 64 20 74 68 | 65 20 64 69 73 74 72 69 |n and th|e distri|
|00005ca0| 62 75 74 69 6f 6e 20 6f | 66 20 74 68 65 20 47 6f |bution o|f the Go|
|00005cb0| 6c 67 69 20 61 70 70 61 | 72 61 74 75 73 20 69 6e |lgi appa|ratus in|
|00005cc0| 20 68 65 74 65 72 6f 6b | 61 72 79 6f 6e 73 00 4d | heterok|aryons.M|
|00005cd0| 69 6c 6c 65 72 20 53 43 | 2c 20 50 61 76 6c 61 74 |iller SC|, Pavlat|
|00005ce0| 68 20 47 4b 2c 20 42 6c | 61 6b 65 6c 79 20 42 54 |h GK, Bl|akely BT|
|00005cf0| 2c 20 42 6c 61 75 20 48 | 4d 00 47 65 6e 65 73 20 |, Blau H|M.Genes |
|00005d00| 26 20 44 65 76 65 6c 6f | 70 6d 65 6e 74 00 32 00 |& Develo|pment.2.|
|00005d10| 33 33 30 2d 33 34 30 00 | 31 39 38 38 00 4a 00 00 |330-340.|1988.J..|
|00005d20| 00 48 65 74 65 72 6f 6b | 61 72 79 6f 6e 73 3b 20 |.Heterok|aryons; |
|00005d30| 47 6f 6c 67 69 20 61 70 | 70 61 72 61 74 75 73 3b |Golgi ap|paratus;|
|00005d40| 20 67 65 6e 65 20 65 78 | 70 72 65 73 73 69 6f 6e | gene ex|pression|
|00005d50| 3b 20 6f 72 67 61 6e 65 | 6c 6c 65 73 3b 20 74 72 |; organe|lles; tr|
|00005d60| 61 6e 73 2d 61 63 74 69 | 6e 67 20 66 61 63 74 6f |ans-acti|ng facto|
|00005d70| 72 73 00 07 58 00 01 78 | 1d 14 02 08 05 02 01 01 |rs..X..x|........|
|00005d80| 00 00 54 72 61 6e 73 2d | 61 63 74 69 6e 67 20 70 |..Trans-|acting p|
|00005d90| 72 6f 74 65 69 6e 20 66 | 61 63 74 6f 72 73 20 61 |rotein f|actors a|
|00005da0| 6e 64 20 74 68 65 20 72 | 65 67 75 6c 61 74 69 6f |nd the r|egulatio|
|00005db0| 6e 20 6f 66 20 65 75 6b | 61 72 79 6f 74 69 63 20 |n of euk|aryotic |
|00005dc0| 74 72 61 6e 73 63 72 69 | 70 74 69 6f 6e 3a 20 20 |transcri|ption:  |
|00005dd0| 4c 65 73 73 6f 6e 73 20 | 66 72 6f 6d 20 73 74 75 |Lessons |from stu|
|00005de0| 64 69 65 73 20 6f 6e 20 | 44 4e 41 20 74 75 6d 6f |dies on |DNA tumo|
|00005df0| 72 20 76 69 72 75 73 65 | 73 00 4a 6f 6e 65 73 20 |r viruse|s.Jones |
|00005e00| 4e 43 2c 20 52 69 67 62 | 79 20 50 57 4a 2c 20 5a |NC, Rigb|y PWJ, Z|
|00005e10| 69 66 66 20 45 42 00 47 | 65 6e 65 73 20 26 20 44 |iff EB.G|enes & D|
|00005e20| 65 76 65 6c 6f 70 6d 65 | 6e 74 00 32 00 32 36 37 |evelopme|nt.2.267|
|00005e30| 2d 32 38 31 00 31 39 38 | 38 00 4a 00 00 00 72 65 |-281.198|8.J...re|
|00005e40| 76 69 65 77 3b 20 67 65 | 6e 65 20 74 72 61 6e 73 |view; ge|ne trans|
|00005e50| 63 72 69 70 74 69 6f 6e | 3b 20 67 65 6e 65 20 65 |cription|; gene e|
|00005e60| 78 70 72 65 73 73 69 6f | 6e 3b 20 76 69 72 75 73 |xpressio|n; virus|
|00005e70| 65 73 3b 20 74 72 61 6e | 73 2d 61 63 74 69 6e 67 |es; tran|s-acting|
|00005e80| 20 66 61 63 74 6f 72 73 | 3b 00 07 59 00 01 62 48 | factors|;..Y..bH|
|00005e90| 0e 02 0a 05 02 01 01 00 | 00 44 65 66 69 6e 69 74 |........|.Definit|
|00005ea0| 69 6f 6e 20 6f 66 20 72 | 65 67 69 6f 6e 73 20 69 |ion of r|egions i|
|00005eb0| 6e 20 68 75 6d 61 6e 20 | 63 2d 6d 79 63 20 74 68 |n human |c-myc th|
|00005ec0| 61 74 20 61 72 65 20 69 | 6e 76 6f 6c 76 65 64 20 |at are i|nvolved |
|00005ed0| 69 6e 20 74 72 61 6e 73 | 66 6f 72 6d 61 74 69 6f |in trans|formatio|
|00005ee0| 6e 20 61 6e 64 20 6e 75 | 63 6c 65 61 72 20 6c 6f |n and nu|clear lo|
|00005ef0| 63 61 6c 69 7a 61 74 69 | 6f 6e 00 53 74 6f 6e 65 |calizati|on.Stone|
|00005f00| 20 4a 2c 20 4c 61 6e 67 | 65 20 54 20 64 65 2c 20 | J, Lang|e T de, |
|00005f10| 52 61 6d 73 61 79 20 47 | 2c 20 4a 61 6b 6f 62 6f |Ramsay G|, Jakobo|
|00005f20| 76 69 74 73 20 45 2c 20 | 42 69 73 68 6f 70 20 4a |vits E, |Bishop J|
|00005f30| 4d 2c 20 56 61 72 6d 75 | 73 20 48 2c 20 4c 65 65 |M, Varmu|s H, Lee|
|00005f40| 20 57 00 4d 6f 6c 20 43 | 65 6c 6c 20 42 69 6f 6c | W.Mol C|ell Biol|
|00005f50| 00 37 00 31 36 39 37 2d | 31 37 30 39 00 31 39 38 |.7.1697-|1709.198|
|00005f60| 37 00 4a 00 00 00 68 75 | 6d 61 6e 3b 6f 6e 63 6f |7.J...hu|man;onco|
|00005f70| 67 65 6e 65 3b 63 2d 6d | 79 63 3b 66 75 6e 63 74 |gene;c-m|yc;funct|
|00005f80| 69 6f 6e 61 6c 20 64 6f | 6d 61 69 6e 73 3b 44 4e |ional do|mains;DN|
|00005f90| 41 20 62 69 6e 64 69 6e | 67 20 70 72 6f 74 65 69 |A bindin|g protei|
|00005fa0| 6e 3b 20 6e 75 63 6c 65 | 61 72 20 6c 6f 63 61 6c |n; nucle|ar local|
|00005fb0| 69 7a 61 74 69 6f 6e 20 | 73 69 67 6e 61 6c 3b 74 |ization |signal;t|
|00005fc0| 72 61 6e 73 66 6f 72 6d | 61 74 69 6f 6e 3b 00 07 |ransform|ation;..|
|00005fd0| 5a 00 01 78 1a 0c 04 0a | 05 02 01 01 00 00 53 70 |Z..x....|......Sp|
|00005fe0| 65 63 69 66 69 63 20 62 | 6c 6f 63 6b 65 72 73 20 |ecific b|lockers |
|00005ff0| 6f 66 20 6d 79 6f 62 6c | 61 73 74 20 66 75 73 69 |of myobl|ast fusi|
|00006000| 6f 6e 20 69 6e 68 69 62 | 69 74 20 61 20 73 6f 6c |on inhib|it a sol|
|00006010| 75 62 6c 65 20 61 6e 64 | 20 6e 6f 74 20 74 68 65 |uble and| not the|
|00006020| 20 6d 65 6d 62 72 61 6e | 65 2d 61 73 73 6f 63 69 | membran|e-associ|
|00006030| 61 74 65 64 20 6d 65 74 | 61 6c 6c 6f 65 6e 64 6f |ated met|alloendo|
|00006040| 70 72 6f 74 65 61 73 65 | 20 69 6e 20 6d 79 6f 62 |protease| in myob|
|00006050| 6c 61 73 74 73 00 43 6f | 75 63 68 20 43 42 2c 20 |lasts.Co|uch CB, |
|00006060| 53 74 72 69 74 74 6d 61 | 74 74 65 72 20 57 4a 00 |Strittma|tter WJ.|
|00006070| 4a 20 42 69 6f 6c 20 43 | 68 65 6d 00 32 35 39 00 |J Biol C|hem.259.|
|00006080| 35 33 39 36 2d 35 33 39 | 39 00 31 39 38 34 00 4a |5396-539|9.1984.J|
|00006090| 00 00 00 72 61 74 3b 4c | 36 3b 53 6e 65 6c 6c 20 |...rat;L|6;Snell |
|000060a0| 72 65 61 64 69 6e 67 73 | 3b 6d 65 74 61 6c 6c 6f |readings|;metallo|
|000060b0| 65 6e 64 6f 70 72 6f 74 | 65 61 73 65 2f 4d 45 50 |endoprot|ease/MEP|
|000060c0| 72 3b 6d 79 6f 62 6c 61 | 73 74 20 66 75 73 69 6f |r;myobla|st fusio|
|000060d0| 6e 3b 20 70 68 65 6e 61 | 6e 74 68 72 6f 6c 69 6e |n; phena|nthrolin|
|000060e0| 65 3b 73 6f 6c 75 62 6c | 65 3b 6d 65 6d 62 72 61 |e;solubl|e;membra|
|000060f0| 6e 65 2d 61 73 73 6f 63 | 69 61 74 65 64 3b 70 68 |ne-assoc|iated;ph|
|00006100| 6f 73 70 68 6f 72 61 6d | 69 64 6f 6e 3b 6d 79 6f |osphoram|idon;myo|
|00006110| 67 65 6e 65 73 69 73 3b | 69 6e 68 69 62 69 74 00 |genesis;|inhibit.|
|00006120| 07 5b 00 01 52 1e 1b 04 | 08 05 02 01 01 00 00 54 |.[..R...|.......T|
|00006130| 68 65 20 73 6f 6c 75 62 | 6c 65 20 6d 65 74 61 6c |he solub|le metal|
|00006140| 6c 6f 65 6e 64 6f 70 72 | 6f 74 65 61 73 65 20 72 |loendopr|otease r|
|00006150| 65 71 75 69 72 65 64 20 | 69 6e 20 6d 79 6f 62 6c |equired |in myobl|
|00006160| 61 73 74 20 66 75 73 69 | 6f 6e 20 72 65 6d 61 69 |ast fusi|on remai|
|00006170| 6e 73 20 69 6e 74 72 61 | 63 65 6c 6c 75 6c 61 72 |ns intra|cellular|
|00006180| 00 46 61 72 61 63 68 20 | 4a 72 20 48 41 2c 20 53 |.Farach |Jr HA, S|
|00006190| 74 72 69 74 74 6d 61 74 | 74 65 72 20 57 4a 00 42 |trittmat|ter WJ.B|
|000061a0| 69 6f 63 68 65 6d 20 42 | 69 6f 70 68 79 73 20 52 |iochem B|iophys R|
|000061b0| 65 73 20 43 6f 6d 6d 75 | 6e 00 31 34 37 00 34 37 |es Commu|n.147.47|
|000061c0| 34 2d 34 37 38 00 31 39 | 38 37 00 4a 00 00 00 4c |4-478.19|87.J...L|
|000061d0| 36 3b 72 61 74 3b 6d 65 | 74 61 6c 6c 6f 65 6e 64 |6;rat;me|talloend|
|000061e0| 6f 70 72 6f 74 65 61 73 | 65 3b 6d 79 6f 67 65 6e |oproteas|e;myogen|
|000061f0| 65 73 69 73 3b 6d 79 6f | 62 6c 61 73 74 20 66 75 |esis;myo|blast fu|
|00006200| 73 69 6f 6e 3b 53 6e 65 | 6c 6c 20 72 65 61 64 69 |sion;Sne|ll readi|
|00006210| 6e 67 73 3b 70 68 65 6e | 61 6e 74 68 72 6f 6c 69 |ngs;phen|anthroli|
|00006220| 6e 65 3b 6d 65 6d 62 72 | 61 6e 65 2d 70 65 72 6d |ne;membr|ane-perm|
|00006230| 65 61 62 6c 65 3b 69 6e | 68 69 62 69 74 6f 72 3b |eable;in|hibitor;|
|00006240| 73 6f 6c 75 62 6c 65 00 | 07 5c 00 01 87 0e 0e 02 |soluble.|.\......|
|00006250| 0a 05 02 01 01 00 00 41 | 20 68 69 65 72 61 72 63 |.......A| hierarc|
|00006260| 68 79 20 6f 66 20 74 72 | 61 6e 73 2d 61 63 74 69 |hy of tr|ans-acti|
|00006270| 6e 67 20 66 61 63 74 6f | 72 73 20 6d 6f 64 75 6c |ng facto|rs modul|
|00006280| 61 74 65 73 20 74 72 61 | 6e 73 6c 61 74 69 6f 6e |ates tra|nslation|
|00006290| 20 6f 66 20 61 6e 20 61 | 63 74 69 76 61 74 6f 72 | of an a|ctivator|
|000062a0| 20 6f 66 20 61 6d 69 6e | 6f 20 61 63 69 64 20 62 | of amin|o acid b|
|000062b0| 69 6f 73 79 6e 74 68 65 | 73 69 73 20 67 65 6e 65 |iosynthe|sis gene|
|000062c0| 73 20 69 6e 20 53 61 63 | 63 68 61 72 6f 6d 79 63 |s in Sac|charomyc|
|000062d0| 65 73 20 63 65 72 65 76 | 69 73 69 61 65 00 48 69 |es cerev|isiae.Hi|
|000062e0| 6e 6e 65 62 75 73 63 68 | 20 41 47 00 4d 6f 6c 20 |nnebusch| AG.Mol |
|000062f0| 43 65 6c 6c 20 42 69 6f | 6c 00 35 00 32 33 34 39 |Cell Bio|l.5.2349|
|00006300| 2d 32 33 36 30 00 31 39 | 38 35 00 4a 00 00 00 59 |-2360.19|85.J...Y|
|00006310| 65 61 73 74 3b 47 43 4e | 3b 20 74 72 61 6e 73 2d |east;GCN|; trans-|
|00006320| 61 63 74 69 6e 67 20 66 | 61 63 74 6f 72 73 3b 53 |acting f|actors;S|
|00006330| 61 63 63 68 61 72 6f 6d | 79 63 65 73 20 63 65 72 |accharom|yces cer|
|00006340| 65 76 69 73 69 61 65 3b | 61 6d 69 6e 6f 20 61 63 |evisiae;|amino ac|
|00006350| 69 64 20 62 69 6f 73 79 | 6e 74 68 65 74 69 63 20 |id biosy|nthetic |
|00006360| 67 65 6e 65 73 3b 74 72 | 61 6e 73 6c 61 74 69 6f |genes;tr|anslatio|
|00006370| 6e 20 72 65 67 75 6c 61 | 74 69 6f 6e 3b 00 07 5d |n regula|tion;..]|
|00006380| 00 01 39 0e 07 04 08 05 | 02 01 01 00 00 56 61 72 |..9.....|.....Var|
|00006390| 69 65 74 79 20 69 6e 20 | 74 68 65 20 6c 65 76 65 |iety in |the leve|
|000063a0| 6c 20 6f 66 20 67 65 6e | 65 20 63 6f 6e 74 72 6f |l of gen|e contro|
|000063b0| 6c 20 69 6e 20 65 75 6b | 61 72 79 6f 74 69 63 20 |l in euk|aryotic |
|000063c0| 63 65 6c 6c 73 00 4a 72 | 20 4a 45 20 44 61 72 6e |cells.Jr| JE Darn|
|000063d0| 65 6c 6c 00 4e 61 74 75 | 72 65 00 32 39 37 00 33 |ell.Natu|re.297.3|
|000063e0| 36 35 2d 33 37 31 00 31 | 39 38 32 00 4a 00 00 00 |65-371.1|982.J...|
|000063f0| 65 75 6b 61 72 79 6f 74 | 65 73 3b 74 72 61 6e 73 |eukaryot|es;trans|
+--------+-------------------------+-------------------------+--------+--------+